{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T15:47:44Z","timestamp":1774712864548,"version":"3.50.1"},"reference-count":34,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,4,10]],"date-time":"2012-04-10T00:00:00Z","timestamp":1334016000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ISRN Dentistry"],"published-print":{"date-parts":[[2012,4,10]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To evaluate the histopathological condition of the pulp in teeth with different levels of chronic periodontitis in humans. <jats:italic>Methods<\/jats:italic>. Twenty-five single-root nondecayed teeth were divided into three groups as follows: group 1, clinical attachment level (CAL) 3 to 4\u2009mm and alveolar bone loss (BL) from 4 to 6\u2009mm without reaching the tooth apex; group 2, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mtext>CAL<\/mml:mtext><mml:mo>\u2265<\/mml:mo><mml:mn>5<\/mml:mn><\/mml:mrow><\/mml:math>\u2009mm and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mtext>BL<\/mml:mtext><mml:mo>&gt;<\/mml:mo><mml:mn>6<\/mml:mn><\/mml:mrow><\/mml:math>\u2009mm without reaching the tooth apex; group 3, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mtext>CAL<\/mml:mtext><mml:mo>\u2265<\/mml:mo><mml:mn>5<\/mml:mn><\/mml:mrow><\/mml:math>\u2009mm and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mtext>BL<\/mml:mtext><mml:mo>&gt;<\/mml:mo><mml:mn>6<\/mml:mn><\/mml:mrow><\/mml:math>\u2009mm up to the tooth apex. Histological analyses were accomplished after laboratorial processing. <jats:italic>Results<\/jats:italic>. The mean of CAL was <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>3.2<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.7<\/mml:mn><\/mml:mrow><\/mml:math>\u2009mm in  group 1, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>7.6<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>2.0<\/mml:mn><\/mml:mrow><\/mml:math>\u2009mm in group 2, and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>12.1<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>2.8<\/mml:mn><\/mml:mrow><\/mml:math>\u2009mm in group 3, while for BL it was <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>4.8<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.9<\/mml:mn><\/mml:mrow><\/mml:math>\u2009mm, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>7.6<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>2.2<\/mml:mn><\/mml:mrow><\/mml:math>\u2009mm, and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>11.9<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>2.1<\/mml:mn><\/mml:mrow><\/mml:math>\u2009mm, respectively. Histopathological data in the pulpal chambers were similar among the three groups showing normal aspects, and, the radicular pulps showed variable levels of reactive dentin, fibrosis, dystrophic mineralizations, atrophy, and mononuclear inflammatory infiltrate. <jats:italic>Conclusions<\/jats:italic>. Gradual progression of the chronic periodontitis led to changes in the histopathological aspects of the radicular pulp with progressive involvement.<\/jats:p>","DOI":"10.5402\/2012\/271350","type":"journal-article","created":{"date-parts":[[2012,4,10]],"date-time":"2012-04-10T21:30:24Z","timestamp":1334093424000},"page":"1-6","source":"Crossref","is-referenced-by-count":11,"title":["Histopathological Features of Dental Pulp in Teeth with Different Levels of Chronic Periodontitis Severity"],"prefix":"10.5402","volume":"2012","author":[{"given":"Elizangela Partata","family":"Zuza","sequence":"first","affiliation":[{"name":"Department of Master of Dental Science, School of Dentistry, Educational Foundation of Barretos (UNIFEB), Avenida Roberto Frade Monte, 389, 14783-226 Barretos, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Luiza Vanzato","family":"Carrareto","sequence":"additional","affiliation":[{"name":"Department of Master of Dental Science, School 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