{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T22:06:23Z","timestamp":1780869983287,"version":"3.54.1"},"reference-count":51,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,10,15]],"date-time":"2012-10-15T00:00:00Z","timestamp":1350259200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ISRN Hematology"],"published-print":{"date-parts":[[2012,10,15]]},"abstract":"<jats:p><jats:italic>Background\/purpose<\/jats:italic>. Transfusion pyrexia (fever) is an important clinical sign\/symptom occurring either as an isolated event or as part of a constellation of signs and symptoms in relation to blood transfusion. It is an important cause of morbidity and may be an important sign of life-threatening complications of blood transfusion. Pyrexia is often a reason for the discontinuation of a blood transfusion episode, and adequate evaluation remains a challenge for clinicians. The decision to stop a blood transfusion episode on account of fever is often a difficult one. This paper reviews the differential diagnosis of transfusion pyrexia (TP), the pathogenesis as well as current management measures.<jats:italic>Study selection and data source<\/jats:italic>. Literature sources include medical texts, journals, dissertations, and internet-based electronic materials<jats:italic>Results and conclusion<\/jats:italic>. Adequate evaluation of pyrexia accompanying blood transfusion remains a challenge for clinicians. An algorithm to assist the clinician in the evaluation of fever occurring in a blood transfusion recipient is developed and presented. Continuous medical education is necessary for clinicians towards improved patient care in transfusion medicine.<\/jats:p>","DOI":"10.5402\/2012\/524040","type":"journal-article","created":{"date-parts":[[2012,10,16]],"date-time":"2012-10-16T09:04:53Z","timestamp":1350378293000},"page":"1-7","source":"Crossref","is-referenced-by-count":5,"title":["Evaluation of Transfusion Pyrexia: A Review of Differential Diagnosis and Management"],"prefix":"10.5402","volume":"2012","author":[{"given":"Oladimeji P.","family":"Arewa","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada T6G 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