{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:44:03Z","timestamp":1790786643922,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,6,14]],"date-time":"2012-06-14T00:00:00Z","timestamp":1339632000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ISRN Hematology"],"published-print":{"date-parts":[[2012,6,14]]},"abstract":"<jats:p>Thalassemia and other structural haemoglobinopathies are the major erythrocyte formation disorder prevalent in certain parts of the world including Bangladesh. We investigated 600 cases of anaemic patients referred from various parts of the country for diagnosis and counselling during 3 months (April to June 2011) of time. The most common form of haemoglobin (Hb) formation disorder observed in 600 subjects studied was \u03b2-thalassemia minor (21.3%). Two other conditions, such as E-\u03b2-Thalassemia and HbE trait, were also fairly common (13.5 and 12.1%, resp.) in the total subjects studied. Other forms of haemoglobin formation disorders observed were HbE disease (9.2%), Hb D\/S trait (0.7%), \u03b2-thalassemia major (0.5%), and \u03b4-\u03b2-thalassemia (0.5%). The majority of the haemoglobinopathies belonged to neonatal to childhood period (0\u201315 years), followed by reproductive age group (16\u201345 years). Few old-age (46<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mo>+<\/mml:mo><\/mml:math>years) cases were also detected in course of clinical complications.<\/jats:p>","DOI":"10.5402\/2012\/659191","type":"journal-article","created":{"date-parts":[[2012,6,18]],"date-time":"2012-06-18T22:00:40Z","timestamp":1340056840000},"page":"1-6","source":"Crossref","is-referenced-by-count":10,"title":["Pattern of<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mi mathvariant=\"bold\">\u03b2<\/mml:mi><\/mml:math>-Thalassemia and Other Haemoglobinopathies: A Cross-Sectional Study in Bangladesh"],"prefix":"10.5402","volume":"2012","author":[{"given":"M. Mesbah","family":"Uddin","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka 1000, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharif","family":"Akteruzzaman","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka 1000, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taibur","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka 1000, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. K. M. Mahbub","family":"Hasan","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka 1000, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossain Uddin","family":"Shekhar","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka 1000, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"1","key":"1","first-page":"131","volume":"7","year":"2007","journal-title":"Journal of Medical Sciences"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1038\/nm0896-847"},{"issue":"1","key":"3","first-page":"2","volume":"20","year":"2002","journal-title":"Indian Journal of Hematology and Blood Transfusion"},{"issue":"3","key":"4","doi-asserted-by":"crossref","first-page":"391","DOI":"10.5858\/2001-125-0391-TNHASX","volume":"125","year":"2001","journal-title":"Archives of Pathology and Laboratory Medicine"},{"key":"5","first-page":"307","volume-title":"Thaseemias","year":"1999"},{"issue":"6","key":"6","first-page":"500","volume":"34","year":"1993","journal-title":"Singapore Medical Journal"},{"issue":"3","key":"7","first-page":"267","volume":"31","year":"1994","journal-title":"Indian Pediatrics"},{"issue":"2","key":"8","first-page":"63","volume":"59","year":"2005","journal-title":"Acta Medica Okayama"},{"issue":"4","key":"9","doi-asserted-by":"crossref","first-page":"299","DOI":"10.3109\/03630269709000664","volume":"21","year":"1997","journal-title":"Hemoglobin"},{"issue":"6","key":"10","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1097\/00043426-200011000-00022","volume":"22","year":"2000","journal-title":"Journal of Pediatric Hematology\/Oncology"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1038\/178695a0"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2002.03539.x"},{"issue":"1","key":"13","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0950-3536(11)80042-9","volume":"5","year":"1992","journal-title":"Bailliere's Clinical Haematology"},{"issue":"6","key":"14","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/j.1365-2141.1973.tb01697.x","volume":"24","year":"1973","journal-title":"British Journal of Haematology"},{"issue":"3","key":"15","doi-asserted-by":"crossref","first-page":"249","DOI":"10.2105\/AJPH.73.3.249","volume":"73","year":"1983","journal-title":"American Journal of Public Health"},{"key":"16","first-page":"137","volume-title":"Disorders of hemoglobin structure and synthesis","year":"1996"},{"issue":"1","key":"17","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3109\/03630268609072474","volume":"10","year":"1986","journal-title":"Hemoglobin"}],"container-title":["ISRN Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/2012\/659191.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2012\/659191.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2012\/659191.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T22:39:14Z","timestamp":1642545554000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/isrn\/2012\/659191\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,14]]},"references-count":17,"alternative-id":["659191","659191"],"URL":"https:\/\/doi.org\/10.5402\/2012\/659191","relation":{},"ISSN":["2090-4428"],"issn-type":[{"value":"2090-4428","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,14]]}}}