{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T13:55:20Z","timestamp":1778680520419,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,9,11]],"date-time":"2012-09-11T00:00:00Z","timestamp":1347321600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001412","name":"Council\u00a0of\u00a0Scientific and Industrial Research, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ISRN Organic Chemistry"],"published-print":{"date-parts":[[2012,9,11]]},"abstract":"A series of novel 4-amino-5-mercapto-3-[(3-aralkyl amido\/imidoalkyl) phenyl]-1,2,4-triazoles (5a-d<\/jats:bold>) were obtained by treating m<\/jats:italic>-(aralkyl amido\/imidoalkyl) benzoic acid hydrazides (3a-d<\/jats:bold>) with carbon disulphide in alcoholic KOH and hydrazine hydrate, respectively. These triazole derivatives were employed in the synthesis of 5-[(3\u2032-aralkyl amido\/imidoalkyl) phenyl]-1,2,4-triazolo[3,4-b<\/jats:italic>]-1,3,4-thiadiazines (6a-d<\/jats:bold>). The newly synthesized compounds were evaluated for their antiviral activity against two animal viruses, namely, Japanese encephalitis virus<\/jats:italic> (JEV) strain P20778 and herpes simplex virus-1<\/jats:italic> (HSV-1) strain 753166.<\/jats:p>","DOI":"10.5402\/2012\/760517","type":"journal-article","created":{"date-parts":[[2012,9,12]],"date-time":"2012-09-12T02:52:33Z","timestamp":1347418353000},"page":"1-7","source":"Crossref","is-referenced-by-count":14,"title":["Synthesis and Biological Evaluation of Some Novel 5-[(3-Aralkyl Amido\/Imidoalkyl) Phenyl]-1,2,4-Triazolo[3,4-b<\/i>]-1,3,4-Thiadiazines as Antiviral Agents"],"prefix":"10.5402","volume":"2012","author":[{"given":"Vinod Kumar","family":"Pandey","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Lucknow, Lucknow 226 007, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zehra","family":"Tusi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Lucknow, Lucknow 226 007, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumerah","family":"Tusi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Lucknow, Lucknow 226 007, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhawanand","family":"Joshi","sequence":"additional","affiliation":[{"name":"Division of Microbiology, Central Drug Research Institute, Lucknow 226001, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2009.06.026"},{"issue":"1","key":"2","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1155\/2012\/867637","volume":"9","year":"2012","journal-title":"E-Journal of Chemistry"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2011.08.019"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2011.09.020"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1515\/hc-2011-0051"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2011.06.024"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2010.08.023"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2010.01.030"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-827X(01)01124-7"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1080\/15257770802271771"},{"issue":"3","key":"11","first-page":"326","volume":"98","year":"2010","journal-title":"Current Science"},{"issue":"5","key":"12","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1128\/AM.22.5.797-801.1971","volume":"22","year":"1971","journal-title":"Applied Microbiology"},{"key":"13","first-page":"791","volume":"34","year":"1995","journal-title":"Indian Journal of Chemistry B"},{"issue":"6","key":"14","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1021\/np50024a015","volume":"45","year":"1982","journal-title":"Journal of Natural Products"},{"issue":"8","key":"15","first-page":"532","volume":"36","year":"1999","journal-title":"Indian Drugs"},{"key":"16","year":"1964"},{"issue":"3","key":"17","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/oxfordjournals.aje.a118408","volume":"27","year":"1938","journal-title":"American Journal of Epidemiology"},{"issue":"1","key":"18","first-page":"1","volume":"54","year":"2004","journal-title":"Acta Pharmaceutica"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1007\/BF00798788"},{"key":"20","year":"2010"},{"issue":"6","key":"21","first-page":"97","volume":"2","year":"2011","journal-title":"Der Chemica Sinica"}],"container-title":["ISRN Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/2012\/760517.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2012\/760517.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2012\/760517.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T00:21:40Z","timestamp":1607559700000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/isrn\/2012\/760517\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,11]]},"references-count":21,"alternative-id":["760517","760517"],"URL":"https:\/\/doi.org\/10.5402\/2012\/760517","relation":{},"ISSN":["2090-5157"],"issn-type":[{"value":"2090-5157","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,11]]}}}