{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T04:40:48Z","timestamp":1791434448554,"version":"4.3.3"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,10,22]],"date-time":"2013-10-22T00:00:00Z","timestamp":1382400000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100007866","name":"College of Medicine and Health Sciences, University of Gondar","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007866","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ISRN Parasitology"],"published-print":{"date-parts":[[2013,10,22]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. The aim of this study was to evaluate the operational characteristics (sensitivity and negative predictive value (NPV)) of wet mount, formol-ether concentration (FEC), and Kato-Katz techniques for the determination of intestinal parasitic infections. <jats:italic>Method<\/jats:italic>. A total of 354 faecal specimens were collected from students in Northwest Ethiopia and screened with Kato-Katz, wet mount, and FEC for the presence of intestinal parasitic infection. Since a gold standard test is not available for detection of intestinal parasites, the combined results from the three methods were used as diagnostic gold standard. <jats:italic>Result<\/jats:italic>. The prevalences of intestinal parasites using the single wet mount, FEC, and Kato-Katz thick smear techniques were 38.4%, 57.1%, and 59%, respectively. Taking the combined results of three techniques as a standard test for intestinal parasitic infection, the sensitivity and negative predictive value  of Kato-Katz is 81.0% (confidence interval (CI)\u2009=\u20090.793\u20130.810) and 66.2% (CI\u2009=\u20090.63\u20130.622), respectively. The FEC detected 56 negative samples that were positive by the gold standard, indicating 78.3% (CI\u2009=\u20090.766\u20130.783) and 63.2% (CI\u2009=\u20090.603\u201363) sensitivity and NPV, respectively. Furthermore, Kato-Katz detects 113 cases that were negative by a single wet mount. The <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>\u03ba<\/mml:mi><\/mml:mrow><\/mml:math> agreement between the wet mount and Kato-Katz methods for the diagnosis of <jats:italic>Ascaris lumbricoides<\/jats:italic> and hookworm was substantial (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>\u03ba<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.61<\/mml:mn><\/mml:mrow><\/mml:math> for <jats:italic>Ascaris lumbricoides<\/jats:italic>, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>\u03ba<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.65<\/mml:mn><\/mml:mrow><\/mml:math> for hookworm).<\/jats:p>","DOI":"10.5402\/2013\/180439","type":"journal-article","created":{"date-parts":[[2012,10,22]],"date-time":"2012-10-22T21:05:27Z","timestamp":1350939927000},"page":"1-5","source":"Crossref","is-referenced-by-count":35,"title":["Comparison of the Kato-Katz, Wet Mount, and Formol-Ether Concentration Diagnostic Techniques for Intestinal Helminth Infections in Ethiopia"],"prefix":"10.5402","volume":"2013","author":[{"given":"Mengistu","family":"Endris","sequence":"first","affiliation":[{"name":"School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zinaye","family":"Tekeste","sequence":"additional","affiliation":[{"name":"School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wossenseged","family":"Lemma","sequence":"additional","affiliation":[{"name":"School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afework","family":"Kassu","sequence":"additional","affiliation":[{"name":"School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","year":"1998"},{"key":"2","first-page":"214","volume-title":"Intestinal parasitism","year":"1988"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182003004128"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2010.08.020"},{"key":"6","year":"1998"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2004.06.011"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-3-71"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000331"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2007.09.009"},{"issue":"4","key":"12","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.parint.2011.06.020","volume":"60","year":"2011","journal-title":"Parasitology International"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2008.11.013"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2009.09.003"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000366"},{"key":"17","year":"1994"},{"issue":"3","key":"18","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/oxfordjournals.aje.a117428","volume":"141","year":"1995","journal-title":"American Journal of Epidemiology"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1111\/j.0006-341X.2004.00183.x"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2006.04.008"},{"issue":"3","key":"23","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1017\/S0031182000056389","volume":"85","year":"1982","journal-title":"Parasitology"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2008.04.005"},{"issue":"7","key":"21","first-page":"1188","volume":"6","year":"2012","journal-title":"Journal of Clinical and Diagnostic Research"}],"container-title":["ISRN Parasitology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/2013\/180439.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2013\/180439.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2013\/180439.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T08:59:24Z","timestamp":1607590764000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/isrn\/2013\/180439\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,22]]},"references-count":20,"alternative-id":["180439","180439"],"URL":"https:\/\/doi.org\/10.5402\/2013\/180439","relation":{},"ISSN":["2314-4076"],"issn-type":[{"value":"2314-4076","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,22]]}}}