{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T15:26:09Z","timestamp":1787671569127,"version":"build-2736575974"},"reference-count":68,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American Academy of Orthopaedic Surgeons"],"published-print":{"date-parts":[[2008]]},"DOI":"10.5435\/00124635-200800001-00012","type":"journal-article","created":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T12:35:56Z","timestamp":1458390956000},"page":"S56-S62","source":"Crossref","is-referenced-by-count":38,"title":["What other biologic and mechanical factors might contribute to osteolysis?"],"prefix":"10.5435","volume":"16","author":[{"given":"Ed M.","family":"Greenfield","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Bechtold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-12-20160319","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/jbm.b.30150","volume":"72","author":"Greenfield","year":"2005","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"R2-12-20160319","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/01.blo.0000175715.68624.3d","volume":"437","author":"Nelson","year":"2005","journal-title":"Clin Orthop Relat Res"},{"key":"R3-12-20160319","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1080\/17453670610045902","volume":"77","author":"Sundfeldt","year":"2006","journal-title":"Acta Orthop"},{"key":"R4-12-20160319","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1080\/17453670710013843","volume":"78","author":"Neut","year":"2007","journal-title":"Acta Orthop"},{"key":"RU5-12-20160319","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/jbm.1264","volume":"59","author":"Akisue","year":"2002","journal-title":"J Biomed Mater Res"},{"key":"RU6-12-20160319","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/S0736-0266(01)00179-6","volume":"20","author":"Cho","year":"2002","journal-title":"J Orthop Res"},{"key":"RU7-12-20160319","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1359\/jbmr.2001.16.11.2082","volume":"16","author":"Bi","year":"2001","journal-title":"J Bone Miner Res"},{"key":"RU8-12-20160319","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/S0736-0266(01)00176-0","volume":"20","author":"Bi","year":"2002","journal-title":"J Orthop Res"},{"key":"RU9-12-20160319","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.2106\/JBJS.F.00615","volume":"89","author":"Smith","year":"2007","journal-title":"J Bone Joint Surg Am"},{"key":"RU10-12-20160319","first-page":"240","volume":"52","author":"Beidelschies","year":"2006","journal-title":"Trans Orthop Res Soc"},{"key":"RU11-12-20160319","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1002\/(SICI)1097-4636(19990905)46:3<434::AID-JBM17>3.0.CO;2-L","volume":"46","author":"Hitchins","year":"1999","journal-title":"J Biomed Mater Res"},{"key":"RU12-12-20160319","first-page":"5","volume":"27","author":"Carmody","year":"2002","journal-title":"Trans Orthop Res Soc"},{"key":"RU13-12-20160319","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1302\/0301-620X.84B2.12061","volume":"84","author":"Brooks","year":"2002","journal-title":"J Bone Joint Surg Br"},{"key":"RU14-12-20160319","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1002\/(SICI)1097-4636(20000315)49:4<469::AID-JBM5>3.0.CO;2-A","volume":"49","author":"Daniels","year":"2000","journal-title":"J Biomed Mater Res"},{"key":"RU15-12-20160319","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/jbm.1230","volume":"59","author":"Charlebois","year":"2002","journal-title":"J Biomed Mater Res"},{"key":"RU16-12-20160319","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/jbm.b.30512","volume":"79","author":"Schwab","year":"2006","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"RU17-12-20160319","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/1097-4636(20010615)55:4<547::AID-JBM1048>3.0.CO;2-Y","volume":"55","author":"Lee","year":"2001","journal-title":"J Biomed Mater Res"},{"key":"RU18-12-20160319","first-page":"696","volume":"52","author":"Gordon","year":"2006","journal-title":"Trans Orthop Res Soc"},{"key":"RU19-12-20160319","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1302\/0301-620X.84B5.11775","volume":"84","author":"Skoglund","year":"2002","journal-title":"J Bone Joint Surg Br"},{"key":"RU20-12-20160319","first-page":"269","volume":"18","author":"Theiss","year":"1993","journal-title":"Trans Orthop Res Soc"},{"key":"R21-12-20160319","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/jor.20289","volume":"25","author":"Tatro","year":"2007","journal-title":"J Orthop Res"},{"key":"RU22-12-20160319","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.orthres.2004.08.023","volume":"23","author":"Taki","year":"2005","journal-title":"J Orthop Res"},{"key":"RU23-12-20160319","first-page":"1792","volume":"32","author":"Illgen","year":"2007","journal-title":"Trans Orthop Res Soc"},{"key":"R24-12-20160319","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1002\/jor.20038","volume":"24","author":"Xing","year":"2006","journal-title":"J Orthop Res"},{"key":"R25-12-20160319","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1056\/NEJMoa061588","volume":"357","author":"Trampuz","year":"2007","journal-title":"N Engl J Med"},{"key":"R26-12-20160319","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00003086-199610000-00003","volume":"331","author":"Mariani","year":"1996","journal-title":"Clin Orthop Relat Res"},{"key":"R27-12-20160319","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/S0076-6879(99)10044-2","volume":"310","author":"Tunney","year":"1999","journal-title":"Methods Enzymol"},{"key":"R28-12-20160319","doi-asserted-by":"crossref","first-page":"3281","DOI":"10.1128\/JCM.37.10.3281-3290.1999","volume":"37","author":"Tunney","year":"1999","journal-title":"J Clin Microbiol"},{"key":"R29-12-20160319","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/01.blo.0000073345.50837.84","volume":"413","author":"","year":"2003","journal-title":"Clin Orthop Relat Res"},{"key":"R30-12-20160319","doi-asserted-by":"crossref","first-page":"R46","DOI":"10.1186\/ar2201","volume":"9","author":"Dempsey","year":"2007","journal-title":"Arthritis Res Ther"},{"key":"R31-12-20160319","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/S0140-6736(75)92553-2","volume":"1","author":"Cooperstock","year":"1975","journal-title":"Lancet"},{"key":"R32-12-20160319","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1348-0421.1991.tb01559.x","volume":"35","author":"Inada","year":"1991","journal-title":"Microbiol Immunol"},{"key":"R33-12-20160319","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1002\/jor.1100170603","volume":"17","author":"Ragab","year":"1999","journal-title":"J Orthop Res"},{"key":"R35-12-20160319","first-page":"358","volume":"31","author":"Nalepka","year":"2006","journal-title":"Trans Orthop Res Soc"},{"key":"R36-12-20160319","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/01.blo.0000224050.94248.38","volume":"451","author":"Nalepka","year":"2006","journal-title":"Clin Orthop Relat Res"},{"key":"R37-12-20160319","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1002\/1529-0131(200010)43:10<2160::AID-ANR3>3.0.CO;2-T","volume":"43","author":"Schrijver","year":"2000","journal-title":"Arthritis Rheum"},{"key":"R38-12-20160319","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1146\/annurev.biochem.76.060605.122847","volume":"76","author":"Lee","year":"2007","journal-title":"Annu Rev Biochem"},{"key":"R39-12-20160319","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/jbm.a.31235","volume":"81","author":"Takagi","year":"2007","journal-title":"J Biomed Mater Res A"},{"key":"R40-12-20160319","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1302\/0301-620X.79B4.7420","volume":"79","author":"Espehaug","year":"1997","journal-title":"J Bone Joint Surg Br"},{"key":"R41-12-20160319","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1080\/00016470310018135","volume":"74","author":"Engesaeter","year":"2003","journal-title":"Acta Orthop Scand"},{"key":"R42-12-20160319","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1126\/science.3629258","volume":"237","author":"Gristina","year":"1987","journal-title":"Science"},{"key":"R43-12-20160319","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/00003086-199401000-00016","volume":"298","author":"Gristina","year":"1994","journal-title":"Clin Orthop Relat Res"},{"key":"R44-12-20160319","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1016\/S0142-9612(02)00614-2","volume":"24","author":"Neut","year":"2003","journal-title":"Biomaterials"},{"key":"R45-12-20160319","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/0968051907078604","volume":"13","author":"Tsan","year":"2007","journal-title":"J Endotoxin Res"},{"key":"R46-12-20160319","doi-asserted-by":"crossref","first-page":"22545","DOI":"10.1074\/jbc.M502900200","volume":"281","author":"Warger","year":"2006","journal-title":"J Biol Chem"},{"key":"R47-12-20160319","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2106\/00004623-200412002-00015","volume":"86","author":"Bragdon","year":"2004","journal-title":"J Bone Joint Surg Am"},{"key":"R48-12-20160319","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/17453679309155636","volume":"1993","author":"Soballe","year":"1993","journal-title":"Acta Orthop Scand Suppl"},{"key":"R49-12-20160319","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1302\/0301-620X.75B2.8444949","volume":"75","author":"Soballe","year":"1993","journal-title":"J Bone Joint Surg Br"},{"key":"R50-12-20160319","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1302\/0301-620X.84B6.12111","volume":"84","author":"Bechtold","year":"2002","journal-title":"J Bone Joint Surg Br"},{"key":"R51-12-20160319","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.2106\/JBJS.D.01882","volume":"87","author":"De Man","year":"2005","journal-title":"J Bone Joint Surg Am"},{"key":"R52-12-20160319","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1080\/000164701317269094","volume":"72","author":"Bechtold","year":"2001","journal-title":"Acta Orthop Scand"},{"key":"R53-12-20160319","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/jbm.a.30983","volume":"81","author":"Goodman","year":"2007","journal-title":"J Biomed Mater Res A"},{"key":"R54-12-20160319","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1002\/(SICI)1097-4636(1999)48:4<434::AID-JBM6>3.0.CO;2-Y","volume":"48","author":"Trindade","year":"1999","journal-title":"J Biomed Mater Res"},{"key":"R55-12-20160319","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/0142-9612(96)81418-9","volume":"17","author":"Aspenberg","year":"1996","journal-title":"Biomaterials"},{"key":"R56-12-20160319","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1080\/17453670510041321","volume":"76","author":"Epstein","year":"2005","journal-title":"Acta Orthop"},{"key":"R57-12-20160319","first-page":"94","volume":"344","author":"Karrholm","year":"1997","journal-title":"Clin Orthop Relat Res"},{"key":"R58-12-20160319","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1080\/00016470510030850","volume":"76","author":"Rahbek","year":"2005","journal-title":"Acta Orthop"},{"key":"R59-12-20160319","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1007\/s00264-005-0008-4","volume":"29","author":"Rahbek","year":"2005","journal-title":"Int Orthop"},{"key":"R60-12-20160319","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/01.blo.0000238777.34939.82","volume":"453","author":"Campbell","year":"2006","journal-title":"Clin Orthop Relat Res"},{"key":"RU61-12-20160319","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/S0736-0266(02)00150-X","volume":"21","author":"Skoglund","year":"2003","journal-title":"J Orthop Res"},{"key":"RU62-12-20160319","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S8756-3282(01)00658-5","volume":"30","author":"McEvoy","year":"2002","journal-title":"Bone"},{"key":"RU63-12-20160319","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/jor.1100180322","volume":"18","author":"Skripitz","year":"2000","journal-title":"J Orthop Res"},{"key":"R64-12-20160319","doi-asserted-by":"crossref","first-page":"337","DOI":"10.3109\/17453679708996173","volume":"68","author":"Overgaard","year":"1997","journal-title":"Acta Orthop Scand"},{"key":"R65-12-20160319","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/j.1600-0501.2006.01308.x","volume":"18","author":"Meirelles","year":"2007","journal-title":"Clin Oral Implants Res"},{"key":"R67-12-20160319","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1002\/jor.20319","volume":"25","author":"Biggs","year":"2007","journal-title":"J Orthop Res"},{"key":"R68-12-20160319","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1615\/JLongTermEffMedImplants.v16.i6.10","volume":"16","author":"Beksac","year":"2006","journal-title":"J Long Term Eff Med Implants"},{"key":"R69-12-20160319","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1359\/jbmr.2003.18.11.1995","volume":"18","author":"Wilkinson","year":"2003","journal-title":"J Bone Miner Res"},{"key":"R70-12-20160319","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1002\/jor.20446","volume":"25","author":"Gordon","year":"2007","journal-title":"J Orthop Res"}],"container-title":["Journal of the American Academy of Orthopaedic Surgeons"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00124635-200800001-00012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T14:44:22Z","timestamp":1787669062000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00124635-200800001-00012"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":68,"URL":"https:\/\/doi.org\/10.5435\/00124635-200800001-00012","relation":{},"ISSN":["1067-151X"],"issn-type":[{"value":"1067-151X","type":"print"}],"subject":[],"published":{"date-parts":[[2008]]}}}