{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:41:20Z","timestamp":1791304880971,"version":"4.3.1"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American Academy of Orthopaedic Surgeons"],"published-print":{"date-parts":[[2008]]},"DOI":"10.5435\/00124635-200800001-00013","type":"journal-article","created":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T12:35:56Z","timestamp":1458390956000},"page":"S63-S67","source":"Crossref","is-referenced-by-count":14,"title":["What experimental approaches (eg, in vivo, in vitro, tissue retrieval) are effective in investigating the biologic effects of particles?"],"prefix":"10.5435","volume":"16","author":[{"given":"Mathias","family":"Bostrom","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regis","family":"O\u02bcKeefe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20160319","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0142-9612(01)00134-X","volume":"23","author":"Wooley","year":"2002","journal-title":"Biomaterials"},{"key":"R2-13-20160319","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1080\/03009740410005944","volume":"33","author":"Ren","year":"2004","journal-title":"Scand J Rheumatol"},{"key":"R3-13-20160319","doi-asserted-by":"crossref","first-page":"2514","DOI":"10.1002\/art.10527","volume":"46","author":"Yang","year":"2002","journal-title":"Arthritis Rheum"},{"key":"R4-13-20160319","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1002\/jbmr.5650111105","volume":"11","author":"Garcia","year":"1996","journal-title":"J Bone Miner Res"},{"key":"R5-13-20160319","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0002-9440(10)65266-2","volume":"154","author":"Merkel","year":"1999","journal-title":"Am J Pathol"},{"key":"R6-13-20160319","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1002\/jor.1100180602","volume":"18","author":"Schwarz","year":"2000","journal-title":"J Orthop Res"},{"key":"R7-13-20160319","first-page":"217","volume":"53","author":"Shi","year":"2007","journal-title":"Trans Orthop Res Soc"},{"key":"R8-13-20160319","first-page":"692","volume":"52","author":"Shi","year":"2006","journal-title":"Trans Orthop Res Soc"},{"key":"R9-13-20160319","first-page":"703","volume":"52","author":"Yang","year":"2006","journal-title":"Trans Orthop Res Soc"},{"key":"R10-13-20160319","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/jbm.b.30875","volume":"84","author":"Ortiz","year":"2008","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"R11-13-20160319","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1302\/0301-620X.78B1.0780032","volume":"78","author":"Allen","year":"1996","journal-title":"J Bone Joint Surg Br"},{"key":"R12-13-20160319","doi-asserted-by":"crossref","first-page":"236","DOI":"10.2106\/00004623-200202000-00011","volume":"84","author":"Millett","year":"2002","journal-title":"J Bone Joint Surg Am"},{"key":"R13-13-20160319","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/S0736-0266(02)00150-X","volume":"21","author":"Skoglund","year":"2003","journal-title":"J Orthop Res"},{"key":"R14-13-20160319","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/(SICI)1097-4636(199822)43:2<123::AID-JBM6>3.0.CO;2-Q","volume":"43","author":"Sacomen","year":"1998","journal-title":"J Biomed Mater Res"},{"key":"R15-13-20160319","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1080\/00016470216314","volume":"73","author":"Sundfeldt","year":"2002","journal-title":"Acta Orthop Scand"},{"key":"R16-13-20160319","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/17453679409155227","volume":"258","author":"Goodman","year":"1994","journal-title":"Acta Orthop Scand Suppl"},{"key":"R17-13-20160319","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/jbm.a.10279","volume":"65","author":"Goodman","year":"2003","journal-title":"J Biomed Mater Res A"},{"key":"R18-13-20160319","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1002\/jbm.a.3000","volume":"65","author":"Goodman","year":"2003","journal-title":"J Biomed Mater Res A"},{"key":"R19-13-20160319","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/jbm.a.30983","volume":"81","author":"Goodman","year":"2007","journal-title":"J Biomed Mater Res A"},{"key":"R20-13-20160319","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1002\/jbm.a.30949","volume":"79","author":"Ma","year":"2006","journal-title":"J Biomed Mater Res A"},{"key":"R21-13-20160319","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1002\/(SICI)1097-4636(1999)48:4<434::AID-JBM6>3.0.CO;2-Y","volume":"48","author":"Trindade","year":"1999","journal-title":"J Biomed Mater Res"},{"key":"R22-13-20160319","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/00003086-199711000-00005","volume":"344","author":"Shanbhag","year":"1997","journal-title":"Clin Orthop Relat Res"},{"key":"R23-13-20160319","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1080\/00016470510030850","volume":"76","author":"Rahbek","year":"2005","journal-title":"Acta Orthop"},{"key":"R24-13-20160319","doi-asserted-by":"crossref","first-page":"4161","DOI":"10.1016\/j.biomaterials.2004.10.020","volume":"26","author":"Coathup","year":"2005","journal-title":"Biomaterials"},{"key":"R25-13-20160319","first-page":"499","volume":"42","author":"Bostrom","year":"1996","journal-title":"Trans Orthop Res Soc"},{"key":"R26-13-20160319","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1002\/(SICI)1097-4636(1999)48:6<899::AID-JBM20>3.0.CO;2-E","volume":"48","author":"Chun","year":"1999","journal-title":"J Biomed Mater Res"},{"key":"R27-13-20160319","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1002\/jor.20486","volume":"26","author":"Koulouvaris","year":"2008","journal-title":"J Orthop Res"}],"container-title":["Journal of the American Academy of Orthopaedic Surgeons"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00124635-200800001-00013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T14:43:03Z","timestamp":1787668983000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00124635-200800001-00013"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":27,"URL":"https:\/\/doi.org\/10.5435\/00124635-200800001-00013","relation":{},"ISSN":["1067-151X"],"issn-type":[{"value":"1067-151X","type":"print"}],"subject":[],"published":{"date-parts":[[2008]]}}}