{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:06:03Z","timestamp":1791486363372,"version":"4.3.4"},"reference-count":0,"publisher":"ScopeMed","issue":"2","license":[{"start":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T00:00:00Z","timestamp":1720915200000},"content-version":"vor","delay-in-days":195,"URL":"https:\/\/bdvets.org\/JAVAR\/?sec=licenseinfo"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Adv Vet Anim Res"],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:p>Objective: The study aims to understand the effect of new antibiotic-substituting supplements in feeding chickens of the Hisex Brown cross in industrial conditions. \nMaterials and Methods: A total of 216 hatched chicks were randomly selected and distributed into Control, Test I, and Test II groups, with 3 replicates of 24 birds in three treatments. \nResults: At the end of the experiment, BW of T1\/T2 birds was higher by 6.12% (p &lt;0.01) and 10.29% (p &lt;0.001) than CON. In comparison with the control hens, T1\/T2 birds had a higher feed conversion rate and digestibility of nutrients. The blood indicators of T1\/T2 hens exceeded those in control. Prebiotic supplementations were positively influenced in the immune indices of birds. IgA, IgG, IgM increased in groups T1\/T2. Similar regularity was found in the natural resistance of chicks fed S1\/S2. In the caecum, the Lactobacilli number was higher than in CON by 17.03% (p &lt;0.01) in T1 and by 18.47% (p &lt;0.01)\u2014in T2; Bifidobacteria\u2014by 17.94 (p &lt;0.001) and 19.09% (p &lt;0.01), respectively; at the same time, the number of E. coli decreased by 21.05% (p &lt;0.01) and 24.21% (p &lt;0.01). The concentration of emitted excreta noxious gases decreased: ammonia by 22.40%\u201324.95% (p &lt;0.01); hydrogen sulfide by 10.67%\u201316.00% (p &lt;0.01); and mercaptans by 12.90%\u201317.74% (p &lt;0.05). \nConclusion: These findings support the use of lactulose-based supplements as antibiotic alterna\u00actives to improve production in poultry farming and to reduce the toxic load on the environment.<\/jats:p>","DOI":"10.5455\/javar.2024.k792","type":"journal-article","created":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T05:30:55Z","timestamp":1720935055000},"page":"429","source":"Crossref","is-referenced-by-count":2,"title":["Lactulose with synergists supplementation improving a health of chicks and reducing the environmental burden in poultry industry"],"prefix":"10.5455","volume":"11","author":[{"given":"Ivan","family":"Gorlov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Slozhenkina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria","family":"Mosolova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyudmila","family":"Khoroshevskaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoya","family":"Komarova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir","family":"Nikulin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgeniya","family":"Struk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksey","family":"Khoroshevsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Anisimova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3407","container-title":["Journal of Advanced Veterinary and Animal Research"],"original-title":[],"link":[{"URL":"https:\/\/ejmanager.com\/mnstemps\/39\/39-1693219050.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:02:21Z","timestamp":1791482541000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejmanager.com\/mnstemps\/39\/39-1693219050.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.5455\/javar.2024.k792","relation":{},"ISSN":["2311-7710"],"issn-type":[{"value":"2311-7710","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}