{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:06:36Z","timestamp":1791486396671,"version":"4.3.4"},"reference-count":0,"publisher":"ScopeMed","issue":"3","license":[{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"vor","delay-in-days":309,"URL":"https:\/\/bdvets.org\/JAVAR\/?sec=licenseinfo"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Adv Vet Anim Res"],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:p>&lt;b&gt;Objective:&lt;\/b&gt; The study assessed the anthelmintic activity of&lt;i&gt; Artemisia absinthium&lt;\/i&gt; ethanolic extract for controlling gastrointestinal nematodes in goats, both &lt;i&gt;in vitro&lt;\/i&gt; using infective larvae and &lt;i&gt;in vivo&lt;\/i&gt; in naturally infected goats under free-grazing conditions in the region of Ayacucho, Peru. \n&lt;b&gt;Materials and Methods:&lt;\/b&gt; For the &lt;i&gt;in vitro&lt;\/i&gt; assay, a larval motility inhibition test was performed on &lt;i&gt;Trichostrongylus&lt;\/i&gt; spp. infective larvae from goats using three different dilutions: 150, 175, and 200 mg\/ml of the plant extract. &lt;i&gt;In vivo&lt;\/i&gt; efficacy was evaluated through the fecal egg count reduction test (FECRT), which was applied to 15 naturally infected Creole goats in one community. Animals were randomly assigned to 3 experimental groups and treated orally with 600 mg\/kg of the plant extract. Fecal samples were collected directly from the rectum on days 0 (pre-treatment) and 7 and 15 post-treatment for egg count analysis. \n&lt;b&gt;Results:&lt;\/b&gt; &lt;i&gt;In vitro&lt;\/i&gt; results showed the highest inhibition of larval motility (81.79%) and larvicidal efficacy (82.2%) at the highest extract concentration (200 mg\/ml). However, the &lt;i&gt;in vivo&lt;\/i&gt; results indicated that &lt;i&gt;A. absinthium&lt;\/i&gt;, at the concentration used, did not exhibit any significant effect on the FECRT. \n&lt;b&gt;Conclusion: &lt;\/b&gt;Although &lt;i&gt;A. absinthium&lt;\/i&gt; showed promising &lt;i&gt;in vitro&lt;\/i&gt; anthelmintic effects, the extract failed to demonstrate significant efficacy &lt;i&gt;in vivo&lt;\/i&gt; at the tested dose. Additionally, continuous monitoring of drugs in the region of study is strongly recommended based on the results obtained for albendazole.<\/jats:p>","DOI":"10.5455\/javar.2025.l960","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T17:46:08Z","timestamp":1762451168000},"page":"1012","source":"Crossref","is-referenced-by-count":2,"title":["&lt;i&gt;In vitro&lt;\/i&gt; and &lt;i&gt;in vivo&lt;\/i&gt; anthelmintic activity of &lt;i&gt;Artemisia absinthium&lt;\/i&gt; against gastrointestinal nematodes of free-grazing goats from Ayacucho, Peru"],"prefix":"10.5455","volume":"12","author":[{"given":"Vania","family":"Flores-Prado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Godoy-Padilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milagros","family":"Limaymanta-Zavala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juancarlos","family":"Cruz-Luis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Z\u00e1rate-Rend\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3407","container-title":["Journal of Advanced Veterinary and Animal Research"],"original-title":[],"link":[{"URL":"https:\/\/www.bibliomed.org\/fulltextpdf.php?mno=215065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:02:53Z","timestamp":1791482573000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bibliomed.org\/?mno=215065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.5455\/javar.2025.l960","relation":{},"ISSN":["2311-7710"],"issn-type":[{"value":"2311-7710","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}