{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:11:09Z","timestamp":1791486669192,"version":"4.3.4"},"reference-count":0,"publisher":"ScopeMed","issue":"1","license":[{"start":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T00:00:00Z","timestamp":1711584000000},"content-version":"vor","delay-in-days":87,"URL":"https:\/\/www.matersociomed.org\/?sec=licenseinfo"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mater Sociomed"],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:p>Background: The rate of multi-drug antibiotic resistance in nosocomial bloodstream infections in elderly patients is increasing. This study examined the data for bloodstream infections to gain a better understanding of bacterial antibiotic resistance. Methods: This was a retrospective study of 817 patients with the first positive blood culture between January 1, 2016 and December 31, 2019. Results: Moyen\u2019s age was 77.4 \u00b1 9.8 years, male (52.4%) and SOFA 5.0 \u00b1 4. ESBL(+) rate was 78\/817 (9.5%). ESBL(+) rate for Escherichia coli and Klebsiella pneumoniae was 69\/141 (48.9%) and 9\/52 (17.3%), respectively. The most common isolates were Escherichia coli (17.3%), Stenotrophomonas maltophilia (13.7%), and Staphylococcus species (23.1%). The rate of septic shock and mortality accounted for 22.3% and 28.9%, respectively. Escherichia coli is highly sensitive to carbapenem, and resistant (&gt;50%) with quinolone and aminoside. Klebsiella pneumoniae and Pseudomonas aeruginosa were highly sensitive to carbapenem. Acinetobacter baumannii was resistant to meropenem (75%). Stenotrophomonas maltophilia was sensitive to quinolone (13.8 %), and highly resistant to remaining antibiotics. Methicillin-resistant Staphylococcus aureus had a low resistance rate for vancomycin, teicoplanin, and linezolid. Multivariate analysis showed that the significant factors associated with mortality were age &gt;75; SOFA &gt;7; respiratory infection; intensive care unit treatment and presentation with septic shock. Conclusion: The mortality rate was still high, especially for antibiotic-resistant agents.<\/jats:p>","DOI":"10.5455\/msm.2024.36.82-89","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T07:15:23Z","timestamp":1711610123000},"page":"82","source":"Crossref","is-referenced-by-count":10,"title":["Blood-Stream Infections: Causative Agents, Antibiotic Resistance and Associated Factors in Older Patients"],"prefix":"10.5455","volume":"36","author":[{"given":"Hoang","family":"Quang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Nhung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pham","family":"Thuy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phan","family":"Quyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Huy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho","family":"Dung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3407","container-title":["Materia Socio Medica"],"original-title":[],"link":[{"URL":"https:\/\/ejmanager.com\/mnstemps\/16\/16-1711544339.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:08:26Z","timestamp":1791482906000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejmanager.com\/mnstemps\/16\/16-1711544339.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.5455\/msm.2024.36.82-89","relation":{},"ISSN":["1512-7680"],"issn-type":[{"value":"1512-7680","type":"print"}],"subject":[],"published":{"date-parts":[[2024]]}}}