{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:11:08Z","timestamp":1791486668565,"version":"4.3.4"},"reference-count":0,"publisher":"ScopeMed","issue":"1","license":[{"start":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T00:00:00Z","timestamp":1741305600000},"content-version":"vor","delay-in-days":65,"URL":"https:\/\/matersociomed.org\/\/?sec=licenseinfo"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mater Sociomed"],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:p>Background: Chronic obstructive pulmonary disease (COPD) is a common global condition, yet real-world data on exacerbations in Vietnamese patients remains limited. This highlights the need for further exploration of clinical complexities in this population. Objective: The aim of this study was to characterize the clinical and paraclinical features of COPD and identify predictors of exacerbation. Methods: A cross-sectional, prospective study was conducted on 180 inpatients at Vietnam National Lung Hospital from January 2016 to June 2021. Clinical and paraclinical data were collected. Results: The mean patient age was 69.38 \u00b1 9.40 years, with 92.8% male. Common symptoms included dyspnea (97.8%), cough (85.6%), and expectoration (80.0%). GOLD stage distribution was: GOLD III (53.7%), GOLD IV (29.3%), and GOLD II (17.0%). Significant predictors of exacerbation included smoking (OR=2.79), comorbidities (OR=3.95), increased dyspnea (OR=14.83), increased sputum (OR=3.13), decreased alveolar murmur (OR=4.11), wheezing (OR=2.70), white blood cell count \u226510 G\/L (OR=4.79), GOLD group D (OR=9.75), and FEV1 &lt;30% (GOLD IV) (OR=7.51) (p &lt; 0.05). Conclusion: Clinical and paraclinical predictors can aid in forecasting and mitigating COPD exacerbations.<\/jats:p>","DOI":"10.5455\/msm.2025.37.32-36","type":"journal-article","created":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T05:36:36Z","timestamp":1741325796000},"page":"32","source":"Crossref","is-referenced-by-count":1,"title":["Clinical and Paraclinical Characteristics and Predictive Factors of Chronic Obstructive Pulmonary Exacerbation"],"prefix":"10.5455","volume":"37","author":[{"given":"Hoang","family":"Thuy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen","family":"Nhung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen","family":"Tien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen","family":"Nguyet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tran","family":"Ly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3407","container-title":["Materia Socio Medica"],"original-title":[],"link":[{"URL":"https:\/\/www.ejmanager.com\/mnstemps\/16\/16-1741337109.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:08:32Z","timestamp":1791482912000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejmanager.com\/mnstemps\/16\/16-1741337109.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.5455\/msm.2025.37.32-36","relation":{},"ISSN":["1512-7680"],"issn-type":[{"value":"1512-7680","type":"print"}],"subject":[],"published":{"date-parts":[[2025]]}}}