{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T15:30:46Z","timestamp":1794324646764,"version":"4.9.0"},"reference-count":0,"publisher":"ScopeMed","issue":"6","license":[{"start":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T00:00:00Z","timestamp":1669161600000},"content-version":"vor","delay-in-days":326,"URL":"http:\/\/www.openveterinaryjournal.com\/?sec=licenseinfo"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Open Vet J"],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:p>Abstract\u2028\nBackround\nThe endolymphatic sac is an organ devoid of sensory receptors. It is connected with the endolymphatic compartment and contains endolymph. Endolymphatic sac tumor is a rare neoplasm involving the middle and inner ear described in humans and dogs, does not show cellular characteristics of malignancy, but can be locally invasive \nand involve destruction of the temporal bone and adjacent structures.\nCase description:\nAn  8 months old female cat was referred because of sudden onset of vestibular\nsigns starting 3 days prior to referral. \nOn clinical examination the patient showed depression, right head-tilt, left sided\nfacial paralysis, horizontal nystagmus with fast phase to the left. \nThe magnetic resonance images showed a voluminous extra axial lesion, with \nirregular morphology and well defined margins, with intracranial extension in\nthe region of the pons, rostral medulla oblongata, cerebellar vermis, floccule\nand left cerebellar hemisphere. \nDue to the progressive clinical deterioration, the cat was euthanized two weeks\nlater. A necropsy was then performed and histological samples taken.\nThe necropsy revealed the presence of a voluminous dark red irregular mass\nextending  from the tympanic bulla to the posterior cranial fossa following the \nleft glossopharyngeal nerve.\nThe histopathologic exam of  the extra-axial lesion featured a non-encapsulated,\nmoderately cellular, rather loose, proliferation of cuboidal to columnar\nepithelium breaching through chunks of an otherwise normal appearing dura\nmater and invading some cranial nerves.\u2028 Sections of the cerebellum and\nbrainstem revealed moderate, focal, impingement of the\nparenchyma with very mild extension of the proliferating cells into the ventral\nleft side of the medulla oblongata.\u2028 Based on these histological characteristics, \nthe lesion was defined as endolymphatic sac tumor, a rare neoplasm described\nin human beings and with 2 reports in dogs.\u2028\u2028\nConclusion\nTo our knowledge, this is the first report describing an endolymphatic sac tumor\nin a cat.\u2028<\/jats:p>","DOI":"10.5455\/ovj.2022.v12.i3.3","type":"journal-article","created":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T04:06:47Z","timestamp":1669176407000},"page":"323","source":"Crossref","is-referenced-by-count":2,"title":["Endolymphatic sac tumor in a 8 months old cat"],"prefix":"10.5455","volume":"12","author":[{"given":"Matteo","family":"Baccolini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Rosati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Tirrito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Cozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rocco","family":"Lombardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3407","container-title":["Open Veterinary Journal"],"original-title":[],"link":[{"URL":"https:\/\/ejmanager.com\/mnstemps\/100\/100-1643192669.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:15:22Z","timestamp":1791483322000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejmanager.com\/mnstemps\/100\/100-1643192669.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.5455\/ovj.2022.v12.i3.3","relation":{},"ISSN":["2226-4485"],"issn-type":[{"value":"2226-4485","type":"print"}],"subject":[],"published":{"date-parts":[[2022]]}}}