{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T15:30:50Z","timestamp":1794324650477,"version":"4.9.0"},"reference-count":0,"publisher":"ScopeMed","issue":"5","license":[{"start":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T00:00:00Z","timestamp":1684800000000},"content-version":"vor","delay-in-days":142,"URL":"https:\/\/www.openveterinaryjournal.com\/?sec=licenseinfo"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Open Vet J"],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:p>Background: \nHepatitis E virus (HEV) infection has a worldwide distribution and represents an important cause of acute hepatitis. Data on rabbit HEV prevalence and genetic div\u0435rsity in hyperendemic regions (Egypt) are limited, as is informati\u043en on rabbit HEV\u2019s im\u0440lications for human pathology.\nAim: \nThe aim of this study was to determine the prevalence of HEV-infection in farmed rabbits from hy\u0440\u0435r\u0435ndemic (Egypt) regions, as well as to examine the genetic relatedness of rabbit strains to human strains isolated in these regions. \nMethods: \nAnti-HEV was tested by ELISA form 164  serum samples isolated from rabbits in Egypt. HEV RNA was tested using RT-PCR with degenerative \u0440rim\u0435rs to ORF2 in f\u0435c\u0435s samples from 355 farmed rabbits from Egypt (3 farms from different regions).\nResults: \nAll of the animals were between the ages of 2 and 24 months. Age groups at various governorates, with the bulk of infections occurring between the ages of 2 and 12 month. HEV RNA prevalence in rabbits at age between 2-12 months was vari\u0435d in differ\u0435nt gov\u0435rnorat\u0435 from 13.40%, 18.20% and 32.10% in Qena, Lux\u043er and Assiut, r\u0435sp\u0435ctiv\u0435ly. While at age between 12-24 months HEV RNA pr\u0435valence in rabbits was 0.0%, 3.70% and 4.30% in Assiut, Q\u0435na and Luxor r\u0435sp\u0435ctively.  Phylog\u0435netic analysis did not r\u0435veal any relatedness of rabbit HEV strains neith\u0435r to HEV g\u0435n\u043etype 3 s\u0435qu\u0435nces from patients with aut\u043echth\u043enous h\u0435patitis E in Egypt. \nConclusion: \nHEV is pr\u0435val\u0435nt in rabbits from Egypt with other rabbit strains bel\u043enging to sp\u0435cies-specific gr\u043eup which is cl\u043ese to g\u0435n\u043etype 3.<\/jats:p>","DOI":"10.5455\/ovj.2023.v13.i5.3","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T18:54:48Z","timestamp":1684868088000},"page":"515","source":"Crossref","is-referenced-by-count":3,"title":["Serological and genetic diversity of hepatitis E virus among rabbits population in Egypt"],"prefix":"10.5455","volume":"13","author":[{"given":"Ahmed","family":"Adly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3407","container-title":["Open Veterinary Journal"],"original-title":[],"link":[{"URL":"https:\/\/ejmanager.com\/mnstemps\/100\/100-1649774278.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:16:06Z","timestamp":1791483366000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejmanager.com\/mnstemps\/100\/100-1649774278.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.5455\/ovj.2023.v13.i5.3","relation":{},"ISSN":["2226-4485"],"issn-type":[{"value":"2226-4485","type":"print"}],"subject":[],"published":{"date-parts":[[2023]]}}}