{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T15:30:57Z","timestamp":1794324657660,"version":"4.9.0"},"reference-count":0,"publisher":"ScopeMed","issue":"0","license":[{"start":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T00:00:00Z","timestamp":1741564800000},"content-version":"vor","delay-in-days":68,"URL":"https:\/\/www.openveterinaryjournal.com\/?sec=licenseinfo"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Open Vet J"],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:p>Background: \nCranberry fruit (Vaccinium macrocarpon L) contains a mixture of phytochemicals like flavonoids which consist of flavonoids, anthocyanins, proanthocyanidins, catechins, phenolic acids, and triterpenoids, all of which have possible antimicrobial (antibacterial, antifungal and antiviral) activity. \n\nAim: \nThis study aimed to determine the antibacterial effect of the ethanol extract of cranberry juice against uropathogen commonly found in urinary tract infections (UTIs) associated with pregnancy. \n\nMethods: \nCranberry fruits were purchased from local markets and juiced, filtered, and dried. The dried powder was extracted with 70% ethanol for 8-10 days. The bacterial isolates used in this study (Escherichia coli, Proteus vulgaris, Staphylococcus aureus, Enterococcus sp., and Coagulase-Negative Staphylococci (CNS)) were collected from the Maternity and Children Hospital in Al-Diwaniyah City, Iraq. The antibacterial activity of the ethanol extract of cranberry juice was measured using a standard Disc diffusion method. Sterile paper discs were soaked in 20 \u00b5L of different concentrations (12.5, 25, 50, and 100 mg\/ml) of the extract, placed in Mueller\u2013Hinton agar plates, and inoculated with bacterial cultures adjusted to 0.5 McFarland standards. Amoxicillin (30 \u00b5g) was used as a positive control, and 70% ethanol was used as negative control. \n\nResults: \nThe ethanol solution of cranberry juice displayed a significant (p&lt;0.05) inhibitory activity against all tested bacteria. The CNS showed the highest sensitivity with 100% inhibition, followed by S. aureus (90%), Enterococcus sp. (85%), P. vulgaris (75%), and E. coli (60%). The effect was dose dependent, as increasing the extract concentration resulted in broader inhibition zones. \n\nConclusion: \nThe results show that the ethanol extract of cranberry juice has potent antibacterial activity against uropathogenic bacteria, suggesting a possible role for cranberry juice ethanol extract in treating UTIs when combined with recently emerging facts about increasing antibiotic resistance<\/jats:p>","DOI":"10.5455\/ovj.2025.v15.i2.30","type":"journal-article","created":{"date-parts":[[2025,3,9]],"date-time":"2025-03-09T20:12:41Z","timestamp":1741551161000},"page":"1","source":"Crossref","is-referenced-by-count":2,"title":["&lt;b&gt;Antimicrobial activity of cranberry juice (&lt;i&gt;Vaccinium macrocarpon&lt;\/i&gt; L.) ethanol extract against uropathogenic bacteria&lt;\/b&gt;"],"prefix":"10.5455","author":[{"given":"Hayder","family":"Kaabi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baheeja","family":"Hmood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3407","container-title":["Open Veterinary Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.ejmanager.com\/mnstemps\/100\/100-1730746484_TYP.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:18:10Z","timestamp":1791483490000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejmanager.com\/mnstemps\/100\/100-1730746484.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":0,"journal-issue":{"issue":"0","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.5455\/ovj.2025.v15.i2.30","relation":{},"ISSN":["2226-4485"],"issn-type":[{"value":"2226-4485","type":"print"}],"subject":[],"published":{"date-parts":[[2025]]}}}