{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T15:31:00Z","timestamp":1794324660226,"version":"4.9.0"},"reference-count":0,"publisher":"ScopeMed","issue":"6","license":[{"start":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T00:00:00Z","timestamp":1752796800000},"content-version":"vor","delay-in-days":198,"URL":"https:\/\/www.openveterinaryjournal.com\/?sec=licenseinfo"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Open Vet J"],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:p>Background: \nCoccidial intestinal infection induces significant economic losses in the production of birds. It also constitutes a major hazard of drug residues to meat consumers if the coccidia is controlled using anticoccidial drugs. \n\nAim: \nThis study aimed to assess the impact of dietary garlic as a natural alternative with or without probiotics compared to the anticoccidial drug against Eimeria infection of broilers. \n\nMethods: \nGrowth rate, carcass dressing, blood metabolites, meat quality, intestinal histomorphology, oocyst shedding, and gene expression were assessed. A total of 150 one-day-old Ross broiler chicks were divided into five groups: NC, negative control; PC, positive control; AC, anticoccidial drug; GR, garlic; GR-P, garlic plus probiotics. The Coccidia challenge was conducted for all experimental groups except NC. \n\nResults: \nPC birds showed a significantly lower weight gain and worse feed conversion ratio compared to the NC birds. The GR-P and AC groups revealed comparable results regarding WG and were significantly higher than the GR and PC groups. In comparison to the PC, AC, and GR-P groups, the GR group exhibited significantly decreased cecal lesion score, mortality rate, and oocyst shedding. GR-P improved carcass traits compared to other groups. GR-P and GR-P showed the highest scores for appearance, juiciness, tenderness, and the overall acceptability of breast meat. GR-P, GR, and AC reduced breast meat PH, TBARS, fat, and ash compared to PC. AC, GR, and GR-P significantly increased jejunal and cecal villus length and crypt depth. Improvements in blood parameters were seen in the AC, GR, and GR-P groups rather than in the PC group. Coccidia challenge significantly induced changes in gene expression levels, while the three additives mainly reversed their expression. \n\nConclusion: \nThe present study reported a promising role of garlic-probiotics dietary supplements in broiler chickens\u2019 growth performance during coccidiosis due to their antioxidant, anticoccidial, and antimicrobial activities.<\/jats:p>","DOI":"10.5455\/ovj.2025.v15.i6.42","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T10:05:07Z","timestamp":1752833107000},"page":"2729","source":"Crossref","is-referenced-by-count":3,"title":["&lt;b&gt;Synergistic effects of garlic powder and probiotics on production and growth performance parameters in broiler challenged with coccidia&lt;\/b&gt;"],"prefix":"10.5455","volume":"15","author":[{"given":"Azhar","family":"Eltanahy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dima","family":"Alkadri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Elmorsy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huda","family":"Emam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nahed","family":"El-Shall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassem","family":"Elmishmishy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asmaa","family":"Elsayyad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gehad","family":"Ezzat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwa","family":"El-Beltagy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Shaalan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radwa","family":"Elzwahary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Sheikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Abdellatif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3407","container-title":["Open Veterinary Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.bibliomed.org\/fulltextpdf.php?mno=255489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:18:42Z","timestamp":1791483522000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.openveterinaryjournal.com\/?mno=255489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.5455\/ovj.2025.v15.i6.42","relation":{},"ISSN":["2226-4485"],"issn-type":[{"value":"2226-4485","type":"print"}],"subject":[],"published":{"date-parts":[[2025]]}}}