{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T15:31:05Z","timestamp":1794324665939,"version":"4.9.0"},"reference-count":0,"publisher":"ScopeMed","issue":"2","license":[{"start":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T00:00:00Z","timestamp":1772236800000},"content-version":"vor","delay-in-days":58,"URL":"https:\/\/www.openveterinaryjournal.com\/?sec=licenseinfo"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Open Vet. J."],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>Background: \nCordarone, a benzofuranic-derivative iodine-rich medication primarily used for tachyarrhythmias, frequently induces alterations in the peripheral metabolism of thyroid hormones, predominantly by inhibiting 5\\'-deiodinase activity, resulting in elevated serum thyroxine and reverse triiodothyronine levels, alongside diminished serum triiodothyronine concentrations. Overt thyroid dysfunction, which manifests as either cordarone-induced thyrotoxicosis (AIT). Linseed oil or flaxseed oil is a type of oil that comes from seeds. It is one of the oldest oils on the market. Solvent-processed flaxseed oil has been used as a drying oil in painting and varnishing for hundreds of years. Raw oil is utilized as an astringent in fungicidal lotion. It also acts as an insecticide and has some insect-repelling effects.\n\nAim: \nThe study sought to show the therapeutic effects of linseed oil on biochemical parameters in rats against toxic effect of cordarone.\n\nMethods: \nIn this study we used twenty  four adult male rats and splited into three groups :control group :drenched standard nutrition only .Cordarone group :drenched cordarone (100mg\/kg\/day) orally by gavage .Cordarone+Linseed oil group: rats were drenched Cordarone (100mg\/kg\/day) and linseed oil(3ml\/kg\/day) for month .at the end of this experiment the rats were scarified and blood samples were taken from the animals for biochemical parameters (ALT, AST, Troponin, TSH, T3 and T4).\n\nResults: \nThe data showed the positive effect of linseed in improving thyroid gland, Heart and liver against the toxic effect of cordarone. \n\nConclusion: \nLinseed had a positive effect against toxic effect of Cordarone  by enhancing hematology parameters. These findings proved benefit of linseed.<\/jats:p>","DOI":"10.5455\/ovj.2026.v16.i2.8","type":"journal-article","created":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T12:03:12Z","timestamp":1772280192000},"page":"841","source":"Crossref","is-referenced-by-count":0,"title":["&lt;b&gt;Assessing the effects of linseed consumption on thyroid hormones and hepatic toxicity in rats drenched with Cordarone overdose&lt;\/b&gt;"],"prefix":"10.5455","volume":"16","author":[{"given":"Moayad","family":"Ubaid","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Abed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaimaa","family":"Jabbar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadiya","family":"Oraibi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shatha","family":"Kadhim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3407","container-title":["Open Veterinary Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.bibliomed.org\/fulltextpdf.php?mno=289978","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:19:49Z","timestamp":1791483589000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.openveterinaryjournal.com\/?mno=289978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.5455\/ovj.2026.v16.i2.8","relation":{},"ISSN":["2226-4485"],"issn-type":[{"value":"2226-4485","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]}}}