{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T01:11:38Z","timestamp":1771981898909,"version":"3.50.1"},"reference-count":0,"publisher":"Sociedad Argentina de Investigacion Odontologica","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Odontol Latinoam"],"abstract":"<jats:p>Fluoridated dentifrices are the most widely used formulations for caries prevention and control.\nHowever, there is great concern regarding legislation on the use of fluoride formulations in early\nchildhood from the standpoint of avoiding increased risk of fluorosis while at the same time achieving a\nconcentration that ensures anticaries activity. AIM: The aim of this study was to evaluate the stability\nof fluoride concentration in the main children\u2019s toothpaste brands marketed in Argentina. Materials and\nMethod: Twenty different brands of children\u2019s toothpaste were evaluated by analyzing the concentration\nof total fluoride (TF), total soluble fluoride (TSF) and ionic fluoride (IF) in two or three samples of each\nbrand. Each sample was analyzed in duplicate using an ion-specific electrode calibrated with fluoride\nstandards, and the results were expressed in ppm (\u03bcg F\/g). Results: TF was found to be lower than stated\nby the manufacturer in 85% of the brands analyzed. TF concentration found in fluoride toothpastes\nranged from 651.5 to 1090.4 \u03bcg\/ml F-, while TSF ranged from 504.2 to 915.5 \u03bcg\/ml F, and IF from\n298.6 to 838.2 \u03bcg\/ml F-. Conclusions: The formulation and fluoride content in children\u2019s toothpastes\nmarketed in Argentina vary greatly according to brand. In all the samples, TF concentration was lower\nthan 1500 ppm F-, and TSF concentration was lower than 1000 ppm F-, the minimum amount necessary\nto ensure anticaries effect. This indicates the need for improved formulations and regulations.<\/jats:p>","DOI":"10.54589\/aol.38\/3\/242","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:52:15Z","timestamp":1771980735000},"page":"242-250","source":"Crossref","is-referenced-by-count":0,"title":["Fluoride content in children\u2019s dentifrices marketed in Argentina"],"prefix":"10.54589","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3308-9120","authenticated-orcid":false,"given":"Ana","family":"Sorazabal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3568-3089","authenticated-orcid":false,"given":"Lidia AR","family":"Valadas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8763-7845","authenticated-orcid":false,"given":"Angela B","family":"Argentieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4232-7178","authenticated-orcid":false,"given":"Pablo","family":"Salgado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1539-2484","authenticated-orcid":false,"given":"Thereza C","family":"Farias Botelho Dantas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3235-8942","authenticated-orcid":false,"given":"Celiane M","family":"Carneiro Tapety","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7687-5805","authenticated-orcid":false,"given":"Aldo","family":"Squassi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"31696","published-online":{"date-parts":[[2025,12,30]]},"container-title":["Acta Odontol\u00f3gica Latinoamericana"],"original-title":[],"deposited":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:52:18Z","timestamp":1771980738000},"score":1,"resource":{"primary":{"URL":"https:\/\/actaodontologicalat.com\/wp-content\/uploads\/2026\/02\/aol_2025_38_3_242.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,30]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,12,30]]}},"URL":"https:\/\/doi.org\/10.54589\/aol.38\/3\/242","relation":{},"ISSN":["1852-4834"],"issn-type":[{"value":"1852-4834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,30]]}}}