{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T11:51:44Z","timestamp":1772625104992,"version":"3.50.1"},"reference-count":24,"publisher":"Korean Society of Interventional Neuroradiology","issue":"2","license":[{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2018R1A2B6003143"],"award-info":[{"award-number":["2018R1A2B6003143"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Science and ICT"}],"content-domain":{"domain":["neurointervention.org"],"crossmark-restriction":true},"short-container-title":["Neurointervention"],"published-print":{"date-parts":[[2022,7,1]]},"abstract":"<jats:p>Purpose: Reversible aggravation of myelopathy symptoms was observed after the intake of taurine-rich foods in patients with venous congestive myelopathy (VCM) caused by a spinal arteriovenous shunt (SAVS), and the taurine-challenge test was applied to demonstrate an association between taurine and VCM.Materials and Methods: The current study reviewed any aggravation history of myelopathy symptoms, including walking difficulty, after consuming taurine-rich foods among 133 consecutive patients with a SAVS from a prospective institutional database from June 2013 to February 2021. The type of taurine-rich foods, demographic data, arteriovenous shunt level, and follow-up periods were obtained. For the controlled taurine challenge test, Bacchus\u00ae (Dong-A Pharmaceutical, Seoul, Korea), a taurine-rich drink, was given to patients who fulfilled test criteria of recovered VCM (pain-sensory-motor-sphincter scale \u22652, improvement of spinal cord signal intensity on magnetic resonance imaging, and follow-up &gt;6 months after SAVS treatment) to confirm the disappearance of such aggravation.Results: Ten patients had an aggravation history related to food. Webfoot octopus, small octopus, squid, crab, scallop, and taurine-rich energy drink (Bacchus\u00ae) were related to such aggravation in patients with VCM. Aggravation appeared about 30 minutes after food intake followed by expressions such as \u2018I could not walk and collapsed to the ground\u2019 and usually lasted for about 3 hours, followed by a slow recovery after taking rest. Four patients who met the test criteria underwent the taurine challenge with Bacchus\u00ae and revealed no further symptom aggravation, suggesting that taurine did not affect patients after recovery from VCM.Conclusion: The association between taurine-rich food and reversible symptom aggravation can appear in patients with VCM and disappear after VCM treatment. Aggravation of venous hypertension in the spinal cord is suggested as a mechanism but further elucidation is needed.<\/jats:p>","DOI":"10.5469\/neuroint.2022.00129","type":"journal-article","created":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:26:08Z","timestamp":1655252768000},"page":"93-99","update-policy":"https:\/\/doi.org\/10.5469\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Reversible Symptom Aggravation by Intake of Taurine-Rich Foods in Patients with Venous Congestive Myelopathy: Controlled Case Series Study"],"prefix":"10.5469","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1561-5596","authenticated-orcid":true,"given":"Dae Chul","family":"Suh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2050-5156","authenticated-orcid":true,"given":"Soo","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5064-2226","authenticated-orcid":true,"given":"Yun Hyeok","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6235-1178","authenticated-orcid":true,"given":"Su Min","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5064-1082","authenticated-orcid":true,"given":"Su Young","family":"Yun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2434-8787","authenticated-orcid":true,"given":"A Yeun","family":"Son","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5074-812X","authenticated-orcid":true,"given":"Young Min","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6113-9730","authenticated-orcid":true,"given":"Boseong","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4738-0533","authenticated-orcid":true,"given":"Yunsun","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3424","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1177\/159101990901500310"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-018-2076-3"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3390\/nu14061292"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3390\/nu13030715"},{"key":"ref5","first-page":"16","volume-title":"Taurine contents in commercial milks, meats and seafoods","author":"Kim","year":"1999"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1123\/ijsnem.20.4.322"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1212\/con.0000000000000583"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1212\/01.con.0000461085.79241.e0"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/brs.0b013e31821352dd"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2016-012267"},{"key":"ref11","first-page":"69","volume-title":"Spinal osseous epidural arteriovenous fistula with multiple small arterial feeders converging to a round fistular nidus as a target of venous approach","author":"Chul Suh","year":"2004"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2017-013150"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00062-016-0541-0"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.a5904"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2016.09.002"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.5469\/neuroint.2012.7.1.10"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-014-0661-8"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2021.102774"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2021.665803"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1038\/s41393-021-00623-7"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2018.2605"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.a1485"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.4062\/biomolther.2017.251"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1139\/apnm-2017-0775"}],"container-title":["Neurointervention"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/neurointervention.org\/upload\/pdf\/neuroint-2022-00129.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/neurointervention.org\/journal\/view.php?doi=10.5469\/neuroint.2022.00129","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/neurointervention.org\/upload\/pdf\/neuroint-2022-00129.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T23:58:47Z","timestamp":1656460727000},"score":1,"resource":{"primary":{"URL":"http:\/\/neurointervention.org\/journal\/view.php?doi=10.5469\/neuroint.2022.00129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,1]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,7]]}},"URL":"https:\/\/doi.org\/10.5469\/neuroint.2022.00129","relation":{},"ISSN":["2093-9043","2233-6273"],"issn-type":[{"value":"2093-9043","type":"print"},{"value":"2233-6273","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,1]]},"assertion":[{"value":"2022-04-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-15","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-01","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}