{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T11:58:41Z","timestamp":1773921521711,"version":"3.50.1"},"reference-count":56,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hamostaseologie"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The aim of this study is to offer physiotherapists a synthesis of the main therapeutic tools available for the treatment of musculoskeletal pathologies in patients with haemophilia, according to the scientific literature. Although bleeds are recognised as no longer being a cause of death for people with haemophilia, the accompanying musculoskeletal injuries now represent the main problem associated with this disorder. There is a lack of clear guidelines to date regarding the physiotherapy treatment of these disorders. We performed a keyword searches of Pubmed, Scopus, Sciencedirect, Cochrane and PEDro databases. In total, 555 references were retrieved, of which only 55 fulfilled the inclusion criteria. Publications were grouped by the main symptoms caused by haemophilia and the physiotherapy treatments available. The literature reviewed shows that physiotherapists have a range of therapeutic tools at their disposal for the treatment of the main musculoskeletal disorders suffered by patients with haemophilia. Physiotherapy interventions act upon inflammation and pain, as well as favouring the reabsorption of haematomas, preventing muscle fibrosis and joint ankylosis and recovering the joint range from prior to the lesions. Also, these interventions help prevent muscle atrophy and provide patients with the optimal physical conditions for facing the small and repetitive injuries that, over time, can have a detrimental effect on their quality of life. Conclusion: Haemophilic patients suffer from a series of musculoskeletal disorders, which are associated with important functional disability. Physiotherapy and adapted sports are essential for decreasing disability and improving the quality of life of affected patients.<\/jats:p>","DOI":"10.5482\/hamo-16-11-0044","type":"journal-article","created":{"date-parts":[[2017,3,14]],"date-time":"2017-03-14T08:17:41Z","timestamp":1489479461000},"page":"141-149","source":"Crossref","is-referenced-by-count":7,"title":["Physiotherapy Treatments in Musculoskeletal Pathologies Associated with Haemophilia"],"prefix":"10.5482","volume":"38","author":[{"given":"Jes\u00fas","family":"Guodemar-P\u00e9rez","sequence":"first","affiliation":[{"name":"Universidad Camilo Jose Cela, Physiotherapy, Villafranca del Castillo, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Montserrat","family":"Ruiz-L\u00f3pez","sequence":"first","affiliation":[{"name":"Universidad Camilo Jose Cela, Nursing, Villafranca del Castillo, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Rodr\u00edguez-L\u00f3pez","sequence":"first","affiliation":[{"name":"Universidad Camilo Jose Cela, Physiotherapy, Villafranca del Castillo, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Garc\u00eda-Fern\u00e1ndez","sequence":"first","affiliation":[{"name":"Universidad Alfonso X El Sabio, Physiotherapy, Villanueva de la Canada, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Pablo","family":"Herv\u00e1s-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Universidad Camilo Jose Cela, Physiotherapy, Villafranca del Castillo, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,9,27]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1136\/mp.55.2.127","article-title":"Haemophilia A and haemophilia B: molecular insights","volume":"55","author":"D J Bowen","year":"2002","journal-title":"Mol Pathol"},{"key":"ref3","first-page":"3","volume-title":"Caracter\u00edsticas generales y cl\u00ednicas de la hemofilia. 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Gu\u00eda de rehabilitaci\u00f3n en hemofilia","author":"A Almend\u00e1riz Ju\u00e1rez","year":"2001"},{"issue":"02","key":"ref8","first-page":"111","article-title":"Lesiones musculoesquel\u00e9ticas en hemofilia","volume":"14","author":"F Querol","year":"2001","journal-title":"Rev Iberoamer Tromb Hemostas"},{"key":"ref9","first-page":"2809","article-title":"Coagulopat\u00eda. Criterios diagn\u00f3sticos y tratamiento","volume":"08","author":"M Viso Sarmiento","year":"2001","journal-title":"Medicine"},{"key":"ref10","first-page":"119","article-title":"Profilaxis primaria en hemofilia","volume":"14","author":"J Tusell","year":"2001","journal-title":"Rev Iberoamer Tromb Hemostasia"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2147\/JBM.S50644","article-title":"Optimal management of hemophilic arthropathy and hematomas","volume":"5","author":"S Lobet","year":"2014","journal-title":"J Blood Med"},{"issue":"03","key":"ref12","doi-asserted-by":"crossref","first-page":"e215","DOI":"10.1111\/j.1365-2516.2011.02680.x","article-title":"The role of ultrasonography in the diagnosis of the musculo-skeletal problems of haemophilia","volume":"18","author":"F Querol","year":"2012","journal-title":"Haemophilia"},{"issue":"02","key":"ref13","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1111\/j.1365-2516.2009.02125.x","article-title":"Cost-effectiveness analysis of different imaging strategies for diagnosis of haemophilic arthropathy","volume":"16","author":"U Khan","year":"2010","journal-title":"Haemophilia"},{"key":"ref14","first-page":"144","article-title":"Problemas ortop\u00e9dicos del ni\u00f1o hemof\u00edlico","volume":"45","author":"F Fern\u00e1ndez Palazzi","year":"2001","journal-title":"Revista de Ortopedia y Traumatolog\u00eda"},{"issue":"S 01","key":"ref15","doi-asserted-by":"crossref","first-page":"S61","DOI":"10.1016\/j.thromres.2013.10.022","article-title":"Early orthopaedic challenges in haemophilia patients and therapeutic approach","volume":"134","author":"A Seuser","year":"2014","journal-title":"Thromb Res"},{"issue":"05","key":"ref16","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1111\/j.1365-2516.2007.01429.x","article-title":"Can early subclinical gait changes in children with haemophilia be identified using the GAITRite walkway","volume":"13","author":"M Bladen","year":"2007","journal-title":"Haemophilia"},{"issue":"06","key":"ref17","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1111\/j.1365-2516.2005.01146.x","article-title":"Haemophilic arthropathy of the elbow. 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Gu\u00eda de rehabilitaci\u00f3n en hemofilia","author":"F Querol Fuentes","year":"2001"},{"issue":"S 03","key":"ref29","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/j.1365-2516.2008.01720.x","article-title":"Orthopaedic management of haemophilia arthropathy of the ankle","volume":"14","author":"G Pasta","year":"2008","journal-title":"Haemophilia"},{"issue":"05","key":"ref30","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1111\/j.1365-2516.2004.00923.x","article-title":"Shoulder hemiarthroplasty to manage haemophilic arthropathy: two case studies","volume":"10","author":"R Dalzell","year":"2004","journal-title":"Haemophilia"},{"issue":"02","key":"ref31","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1111\/hae.12349","article-title":"Comprehensive management of chronic pain in haemophilia","volume":"20","author":"G Young","year":"2014","journal-title":"Haemophilia"},{"issue":"01","key":"ref32","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s002960100117","article-title":"Musculoskeletal pain and functional ability in haemophilia A and B. Physiotherapy and rehabilitation in haemophilia patients","volume":"21","author":"N Santavirta","year":"2001","journal-title":"Rheumatol Int"},{"issue":"02","key":"ref33","doi-asserted-by":"crossref","first-page":"167","DOI":"10.5482\/HAMO-14-03-0021","article-title":"Pain therapy in haemophilia in Germany. Patient survey (BESTH study)","volume":"35","author":"W Kalnins","year":"2015","journal-title":"Hamostaseologie"},{"key":"ref34","first-page":"51","volume-title":"Hematomas musculares. In: Querol Fuentes F dir. Gu\u00eda de rehabilitaci\u00f3n en hemofilia","author":"A Almend\u00e1riz Ju\u00e1rez","year":"2001"},{"issue":"02","key":"ref35","first-page":"111","article-title":"Lesiones musculoesquel\u00e9ticas en hemofilia: hematomas musculares","volume":"14","author":"F Querol","year":"2001","journal-title":"Rev Iberoamer Tromb Hemostasia"},{"issue":"02","key":"ref36","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0048-7120(05)74314-0","article-title":"Rehabilitaci\u00f3n de los hematomas musculares en los pacientes hemof\u00edlicos","volume":"39","author":"R Navarro Monsoliv","year":"2015","journal-title":"Rehabilitaci\u00f3n"},{"issue":"S 01","key":"ref37","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1046\/j.1365-2516.1999.0050s1016.x","article-title":"Physiotherapy for the treatment of articular contractures in haemophilia","volume":"5","author":"L Heijnen","year":"1999","journal-title":"Haemophilia"},{"issue":"04","key":"ref38","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1111\/j.1365-2516.2011.02720.x","article-title":"Management of muscle haematomas in patients with severe haemophilia in an evidence-poor world","volume":"18","author":"B S\u00f8rensen","year":"2012","journal-title":"Haemophilia"},{"issue":"02","key":"ref39","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.arcped.2008.11.007","article-title":"Muscular complications of hemophilia","volume":"16","author":"M Alcalay","year":"2009","journal-title":"Arch Pediatr"},{"key":"ref40","first-page":"9","volume-title":"Valoraci\u00f3n cl\u00ednica del aparato locomotor. In: Querol Fuentes F dir. Gu\u00eda de rehabilitaci\u00f3n en hemofilia","author":"C L\u00f3pez Cabarcos","year":"2001"},{"issue":"01","key":"ref41","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1365-2516.2008.01855.x","article-title":"Conservative physiotherapeutic management of chronic haematomata and haemophilic pseudotumours: case study and comparison to historical management","volume":"15","author":"A I D\u2018Young","year":"2009","journal-title":"Haemophilia"},{"issue":"04","key":"ref42","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s12288-008-0038-3","article-title":"Management of chronic synovitis in patients with hemophilia: with special reference to developing countries","volume":"24","author":"K Ghosh","year":"2008","journal-title":"Indian J Hematol Blood Transfus"},{"key":"ref43","first-page":"43","volume-title":"Sinovitis y sinovioartrosis. In: Querol Fuentes F dir. Gu\u00eda de rehabilitaci\u00f3n en hemofilia","author":"F Querol Fuentes","year":"2001"},{"issue":"03","key":"ref44","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/hae.12061","article-title":"Comparison between pulsed ultrasound and low level laser therapy on experimental haemarthrosis","volume":"19","author":"R Ravanbod","year":"2013","journal-title":"Haemophilia"},{"key":"ref45","first-page":"305249","article-title":"Physiotherapy treatment in patients with hemophilia and chronic ankle arthropathy: a systematic review","volume":"2013","author":"R Cuesta-Barriuso","year":"2013","journal-title":"Rehabil Res Pract"},{"issue":"06","key":"ref46","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1111\/hae.12447","article-title":"Effectiveness of an educational intervention of physiotherapy in parents of children with haemophilia","volume":"20","author":"R Cuesta-Barriuso","year":"2014","journal-title":"Haemophilia"},{"issue":"02","key":"ref47","doi-asserted-by":"crossref","first-page":"e121","DOI":"10.1111\/hae.12355","article-title":"Self-monitoring has potential for home exercise programmes in patients with haemophilia","volume":"20","author":"M Goto","year":"2014","journal-title":"Haemophilia"},{"issue":"04","key":"ref48","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1111\/hae.12118","article-title":"The benefits of exercise for patients with haemophilia and recommendations for safe and effective physical activity. 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Review","volume":"16","author":"G Blamey","year":"2010","journal-title":"Haemophilia"},{"issue":"05","key":"ref51","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1111\/j.1365-2516.2012.02819.x","article-title":"The impact of a specific aqua-training for adult haemophilic patients\u2013results of the WATERCISE study (WAT-QoL)","volume":"18","author":"S Von Mackensen","year":"2012","journal-title":"Haemophilia"},{"issue":"S 01","key":"ref52","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.5482\/HAMO-14-01-0003","article-title":"Climbing therapy under PK-tailored prophylaxis","volume":"34","author":"M Stemberger","year":"2014","journal-title":"Hamostaseologie"},{"issue":"S 01","key":"ref53","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1365-2516.2008.01948.x","article-title":"Haemophilia care in adolescents\u2013compliance and lifestyle issues. 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Review","volume":"15","author":"M Gomis","year":"2009","journal-title":"Haemophilia"},{"issue":"S 02","key":"ref56","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1365-2516.2007.01504.x","article-title":"Enhancing lifestyle for individuals with haemophilia through physical activity and exercise: the role of physiotherapy","volume":"13","author":"K Wittmeier","year":"2007","journal-title":"Haemophilia"},{"issue":"02","key":"ref57","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1055\/s-0031-1286292","article-title":"Haemophilia and exercise","volume":"33","author":"J Cl Souza","year":"2012","journal-title":"Int J Sports Med"},{"issue":"169","key":"ref58","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.apunts.2010.09.002","article-title":"Hemofilia: ejercicio y deporte","volume":"46","author":"S P\u00e9rez-Alenda","year":"2011","journal-title":"Apunts Med Esport"}],"container-title":["H\u00e4mostaseologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.5482\/HAMO-16-11-0044.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T11:28:44Z","timestamp":1685532524000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.5482\/HAMO-16-11-0044"}},"subtitle":["A literature review"],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":56,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2018,9,27]]},"published-print":{"date-parts":[[2018,8]]}},"URL":"https:\/\/doi.org\/10.5482\/hamo-16-11-0044","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0720-9355","2567-5761"],"issn-type":[{"value":"0720-9355","type":"print"},{"value":"2567-5761","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8]]}}}