{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T01:01:44Z","timestamp":1789002104851,"version":"build-2803163510"},"reference-count":44,"publisher":"Korean Society for Biochemistry and Molecular Biology - BMB Reports","issue":"4","license":[{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["2017R1A4A1015652"],"award-info":[{"award-number":["2017R1A4A1015652"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["2020R1A2C3006875"],"award-info":[{"award-number":["2020R1A2C3006875"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["2020R1A2C3006734"],"award-info":[{"award-number":["2020R1A2C3006734"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.bmbreports.org"],"crossmark-restriction":true},"short-container-title":["BMB Rep."],"published-print":{"date-parts":[[2021,4,30]]},"DOI":"10.5483\/bmbrep.2021.54.4.205","type":"journal-article","created":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T01:10:04Z","timestamp":1620004204000},"page":"196-202","update-policy":"https:\/\/doi.org\/10.5483\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["The blood cerebrospinal fluid barrier orchestrates immunosurveillance, immunoprotection, and immunopathology in the central nervous system"],"prefix":"10.5483","volume":"54","author":[{"given":"Maria","family":"Ayub","sequence":"first","affiliation":[{"name":"KNU Alzheimer\u2019s disease Research Institute, Kyungpook National University, Daegu 41566, Korea"},{"name":"Department of Physiology, School of Medicine, Kyungpook National University, Daegu 41944, Korea"},{"name":"Department of Biomedical Science, BK21 Plus KNU Biomedical Convergence Program, Kyungpook National University, Daegu 41944, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee Kyung","family":"Jin","sequence":"additional","affiliation":[{"name":"KNU Alzheimer\u2019s disease Research Institute, Kyungpook National University, Daegu 41566, Korea"},{"name":"Department of Laboratory Animal Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-sung","family":"Bae","sequence":"additional","affiliation":[{"name":"KNU Alzheimer\u2019s disease Research Institute, Kyungpook National University, Daegu 41566, Korea"},{"name":"Department of Physiology, School of Medicine, Kyungpook National University, Daegu 41944, Korea"},{"name":"Department of Biomedical Science, BK21 Plus KNU Biomedical Convergence Program, Kyungpook National University, Daegu 41944, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3442","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.38.2.183"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2006.11.004"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/nature14432"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1172\/JCI67677"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1126\/science.1206936"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.11.8053"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awm295"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S1286-0115(05)83235-7"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/nature08478"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4161\/cam.21054"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2016.08.011"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01078"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/BF00309340"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s004410051287"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1433000100"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1084\/jem.186.6.837"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Liao F, Rabin RL, Smith CS, Sharma G, Nutman TB and Farber JM (1999) CC-chemokine receptor 6 is expressed on diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3 alpha. J Immunol 162, 186-194","DOI":"10.4049\/jimmunol.162.1.186"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1716"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0093057"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2007.07.024"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20049"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80438-9"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1038\/42491"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.02.012"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-017-0909-3"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.5.3084-3087.2004"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-9-7"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1211270110"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20072041"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(98)00077-0"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1089\/neu.1999.16.617"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116549"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(90)90085-S"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/683405"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2004.02870.x"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1038\/srep24646"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2019.04.003"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.1.566"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1227-1"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2015.00138"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2005.11.022"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0029(20010101)52:1<31::AID-JEMT5>3.0.CO;2-T"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/60.7.852"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201591468"}],"container-title":["BMB Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pdf.medrang.co.kr\/BMB\/2021\/054\/BMB054-04-02.pdf","content-type":"unspecified","content-version":"tdm","intended-application":"text-mining"},{"URL":"http:\/\/pdf.medrang.co.kr\/BMB\/2021\/054\/BMB054-04-02.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T04:55:21Z","timestamp":1698987321000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmbreports.org\/journal\/view.html?doi=10.5483\/BMBRep.2021.54.4.205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,30]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4,30]]}},"alternative-id":["10.5483\/BMBRep.2021.54.4.205"],"URL":"https:\/\/doi.org\/10.5483\/bmbrep.2021.54.4.205","relation":{},"ISSN":["1976-670X"],"issn-type":[{"value":"1976-670X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,30]]},"assertion":[{"value":"https:\/\/www.bmbreports.org\/journal\/view.html?doi=10.5483\/BMBRep.2021.54.4.205","URL":"https:\/\/www.bmbreports.org\/journal\/view.html?doi=10.5483\/BMBRep.2021.54.4.205","name":"the_journal","label":"BMB Reports","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2020-09-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-10","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2021 The Korean Society for Biochemistry and Molecular Biology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}