{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:18:06Z","timestamp":1791271086134,"version":"4.1.0"},"reference-count":0,"publisher":"Canadian Urological Association Journal","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CUAJ"],"abstract":"<jats:p>Introduction: We report our experience with endoscopic ablationof Hunner\u2019s lesions in women with interstitial cystitis (IC).Methods: A chart review was performed on 14 patients with ICsymptoms who were identified to have bladder lesions and underwentendoscopic ablation. A Hunner\u2019s lesion was identified asan area of erythema that reproduced the patients\u2019 pain when touchedby the cystoscope. Pathology reports were reviewed and improvementin pain was used as the main outcome measure.Results: Of the 14 patients, 12 had more than 50% symptomaticimprovement and 8 patients reported 100% improvement. Meanimprovement was 76%. In all patients who improved, the biopsyspecimen showed inflammatory cystitis, often with epithelialdenudation. Four patients had symptomatic recurrence, but allhad improvement after repeat ablation.Conclusion: Endoscopic ablation of Hunner\u2019s lesions improves symptomsin IC patients. Recurrence of symptoms should prompt repeatcystoscopy to identify recurrent lesions, as repeat ablation offerssymptomatic improvement.Introduction : L\u2019article fait \u00e9tat de notre exp\u00e9rience concernantl\u2019ablation endoscopique d\u2019ulc\u00e8res de Hunner chez des femmesatteintes de cystite interstitielle (CI).M\u00e9thodologie : On a men\u00e9 un examen des dossiers de 14 patientespr\u00e9sentant des sympt\u00f4mes de CI chez qui des l\u00e9sions v\u00e9sicalesavaient \u00e9t\u00e9 observ\u00e9es et trait\u00e9es par ablation endoscopique. Unulc\u00e8re de Hunner \u00e9tait d\u00e9fini comme une zone d\u2019\u00e9ryth\u00e8me reproduisantla douleur d\u00e9crite par la patiente lorsque cette zone \u00e9taittouch\u00e9e \u00e0 l\u2019aide du cystoscope. Les rapports de pathologie ont\u00e9t\u00e9 examin\u00e9s et la r\u00e9duction de la douleur a \u00e9t\u00e9 utilis\u00e9e commeprincipal crit\u00e8re d\u2019\u00e9valuation.R\u00e9sultats : Sur les 14 patientes, 12 ont pr\u00e9sent\u00e9 une r\u00e9duction sup\u00e9rieure\u00e0 50 % des sympt\u00f4mes et 8 ont signal\u00e9 une r\u00e9duction de 100 %. Letaux moyen de r\u00e9duction \u00e9tait de 76 %. Chez toutes les patientesayant signal\u00e9 une r\u00e9duction des sympt\u00f4mes, l\u2019\u00e9chantillon de tissupr\u00e9lev\u00e9 par biopsie montrait la pr\u00e9sence de cystite inflammatoire,souvent accompagn\u00e9e de d\u00e9nudation \u00e9pith\u00e9liale. Quatre patientesont signal\u00e9 une r\u00e9apparition des sympt\u00f4mes, mais une nouvelle ablationa permis de r\u00e9duire encore une fois les sympt\u00f4mes.Conclusion : L\u2019ablation endoscopique des ulc\u00e8res de Hunner entra\u00eeneune r\u00e9duction des sympt\u00f4mes en pr\u00e9sence de CI. La r\u00e9apparitiondes sympt\u00f4mes devrait \u00eatre prise en charge par une nouvelle cystoscopieafin de rep\u00e9rer les nouvelles l\u00e9sions; une nouvelle ablationpermet de soulager les sympt\u00f4mes.<\/jats:p>","DOI":"10.5489\/cuaj.1178","type":"journal-article","created":{"date-parts":[[2016,10,11]],"date-time":"2016-10-11T07:44:27Z","timestamp":1476171867000},"page":"473","source":"Crossref","is-referenced-by-count":50,"title":["Endoscopic ablation of Hunner\u2019s lesions in interstitial cystitis patients"],"prefix":"10.5489","volume":"3","author":[{"given":"Ryan A.","family":"Payne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Corey","family":"O\u2019Connor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarita","family":"Kressin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael L.","family":"Guralnick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3456","published-online":{"date-parts":[[2013,5,1]]},"container-title":["Canadian Urological Association Journal"],"original-title":[],"link":[{"URL":"http:\/\/www.cuaj.ca\/index.php\/journal\/article\/viewFile\/1178\/970","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.cuaj.ca\/index.php\/journal\/article\/viewFile\/1178\/970","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,9,11]],"date-time":"2017-09-11T11:50:04Z","timestamp":1505130604000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.cuaj.ca\/index.php\/journal\/article\/view\/1178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,1]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2013,5,1]]}},"URL":"https:\/\/doi.org\/10.5489\/cuaj.1178","relation":{},"ISSN":["1920-1214","1911-6470"],"issn-type":[{"value":"1920-1214","type":"electronic"},{"value":"1911-6470","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5,1]]}}}