{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T23:15:09Z","timestamp":1680822909537},"reference-count":0,"publisher":"Canadian Urological Association Journal","issue":"9-10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CUAJ"],"abstract":"<jats:p>&lt;p&gt;&lt;strong&gt;Introduction:&lt;\/strong&gt; Ureteral strictures can result in obstructive nephropathy and renal function deterioration. Surgical management of ureteral defects, especially in the proximal- and mid-ureter, is particularly challenging. Our purpose was to analyze the long-term outcomes of urothelial-based reconstructive surgery for upper- and mid-ureteral defects.&lt;\/p&gt;&lt;p&gt;&lt;strong&gt;Methods:&lt;\/strong&gt; We conducted a retrospective analysis of a single tertiary centre\u2019s database, including 149 patients treated for ureteral defects between 2001 and 2011. Thirty-one patients (21%) underwent complex urothelial-based surgical repairs for upper- and mid-ureter defects. Patients\u2019 median age was 61 years. The mean length of the ureteral strictures was 2.5 cm, located in upper-, mid-ureter, or in between in 19 (61%), 10 (32%), and two (6%) patients, respectively. All patients were treated with a primary urothelial-based repair. Median followup time was 26 months. The primary outcome of the study was the long-term preservation of renal function and lack of clinical obstruction. The secondary endpoint of the study was the assessment of the intra- and postoperative complication rates.&lt;\/p&gt;&lt;p&gt;&lt;strong&gt;Results:&lt;\/strong&gt; Most of the lesions were benign (22, 71%), while nine strictures (29%) were malignant. Seven patients (23%) suffered from postoperative complications, five of which were infectious. The median pre- and postoperative calculated glomerular filtration rates were 66 ml\/min\/1.72m2 and 64ml\/min\/1.72m2, respectively. Success rate was 84%, defined as lack of need for re-operation or kidney drainage at the last followup.&lt;\/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions:&lt;\/strong&gt; Upper- and mid-ureteral defects present a complex pathology necessitating experienced reconstructive surgical skills. Our data suggest good long-term results for primary urothelialbased reconstructions for these pathologies.&lt;\/p&gt;<\/jats:p>","DOI":"10.5489\/cuaj.3659","type":"journal-article","created":{"date-parts":[[2016,9,13]],"date-time":"2016-09-13T18:20:09Z","timestamp":1473790809000},"page":"290","source":"Crossref","is-referenced-by-count":1,"title":["Urothelial-based reconstructive surgery for upper- and mid-ureteral defects: Long-term results"],"prefix":"10.5489","volume":"10","author":[{"given":"Barak","family":"Rosenzweig","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoram","family":"Mor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomer","family":"Erlich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Menachem","family":"Laufer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry","family":"Winkler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Issac","family":"Kaver","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Ramon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zohar A.","family":"Dotan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3456","published-online":{"date-parts":[[2016,9,13]]},"container-title":["Canadian Urological Association Journal"],"original-title":[],"link":[{"URL":"http:\/\/www.cuaj.ca\/index.php\/journal\/article\/viewFile\/3659\/2829","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.cuaj.ca\/index.php\/journal\/article\/viewFile\/3659\/2829","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,9,13]],"date-time":"2016-09-13T18:20:12Z","timestamp":1473790812000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.cuaj.ca\/index.php\/journal\/article\/view\/3659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,13]]},"references-count":0,"journal-issue":{"issue":"9-10","published-online":{"date-parts":[[2016,9,13]]}},"URL":"https:\/\/doi.org\/10.5489\/cuaj.3659","relation":{},"ISSN":["1920-1214"],"issn-type":[{"value":"1920-1214","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,13]]}}}