{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:56:32Z","timestamp":1790517392294,"version":"4.1.0"},"reference-count":0,"publisher":"Canadian Urological Association Journal","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CUAJ"],"abstract":"<jats:p>Introduction: Many clinicians have suggested that a history of bladder and bowel dysfunction (BBD) in childhood predisposes to the development of interstitial cystitis\/bladder pain syndrome (IC\/BPS) or irritable bowel syndrome (IBS) in adulthood. We hypothesized that BBD symptoms in childhood would predict the IBS-associated phenotype in adult IC\/BPS patients.Methods: Consecutive female patients (n=190) with a diagnosis of IC\/BPS were administered a modified form of a clinical BBD questionnaire (BBDQ) to capture childhood BBD-like symptoms, as well as Interstitial Cystitis Symptoms Index (ICSI), Interstitial Cystitis Problem Index (ICPI), Pelvic Pain and Urgency\/ Frequency (PUF) questionnaires and UPOINT categorization. Patients were stratified to IBS-positive or IBS-negative according to clinical assessment of IBS-like symptoms.Results: The 127 patients (67%) identified with IBS-like symptoms recalled significantly higher BBDQ scores than the 63 patients (33%) who were IBS-negative (2.8 vs. 2.3; p=0.05). The IBS-positive patients also reported a higher number of UPOINT domains than their non-IBS counterparts (3.8 vs. 2.9; p=0.0001), while their PUF total scores were significantly higher (13.6 vs. 12.3; p=0.04). IBSpositive patients more often recalled that in childhood they did not have a daily bowel movement (BM) (p=0.04) and had \u201cto push for a BM\u201d (p=0.009). In childhood, they \u201curinated only once or twice per day\u201d (p=0.03) and recalled \u201cpainful urination\u201d more than those without IBS (p=0.03). There were no significant differences between the groups in answers to the other five questions of the BBDQ.Conclusions: Our symptom recollection survey was able to predict the IBS phenotype of IC\/BPS based on a childhood BBDQ. Further prospective studies are needed to further evaluate these novel findings.<\/jats:p>","DOI":"10.5489\/cuaj.4251","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T15:08:32Z","timestamp":1502464112000},"page":"255-9","source":"Crossref","is-referenced-by-count":14,"title":["Childhood bladder and bowel dysfunction predicts irritable bowel syndrome phenotype in adult interstitial cystitis\/bladder pain syndrome patients"],"prefix":"10.5489","volume":"11","author":[{"given":"R. Christopher","family":"Doiron","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry A.","family":"Kogan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Tolls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Irvine-Bird","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Curtis","family":"Nickel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3456","published-online":{"date-parts":[[2017,8,11]]},"container-title":["Canadian Urological Association Journal"],"original-title":[],"link":[{"URL":"https:\/\/cuaj.ca\/index.php\/journal\/article\/download\/4251\/3238","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cuaj.ca\/index.php\/journal\/article\/download\/4251\/3238","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,13]],"date-time":"2019-07-13T10:12:37Z","timestamp":1563012757000},"score":1,"resource":{"primary":{"URL":"https:\/\/cuaj.ca\/index.php\/journal\/article\/view\/4251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,11]]},"references-count":0,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2017,8,11]]}},"URL":"https:\/\/doi.org\/10.5489\/cuaj.4251","relation":{},"ISSN":["1920-1214","1911-6470"],"issn-type":[{"value":"1920-1214","type":"electronic"},{"value":"1911-6470","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8,11]]}}}