{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T06:40:19Z","timestamp":1742884819381,"version":"3.40.2"},"reference-count":26,"publisher":"Baishideng Publishing Group Inc.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Psychiatry"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>Depression is a disorder characterized by significant and persistent depressed mood, cognitive impairment, impaired voluntary activity, working memory, and somatic symptoms.<\/jats:p>\n          <jats:p>AIM<\/jats:p>\n          <jats:p>To determine the efficacy of Qi-based mindfulness therapy (QMT) in treating anxiety, depression, and sleep disturbances in individuals with mild-to-moderate depression.<\/jats:p>\n          <jats:p>METHODS<\/jats:p>\n          <jats:p>A self-controlled before\u2013after trial was conducted. The study invited online participants for recruitment between May and July 2023. Participants (n  = 18) aged 18-65 years with mild-to-moderate depression, who were receiving QMT training for 4 weeks, were included. The primary efficacy indicators were the 17 Hamilton Depression Rating Scale and Hamilton Anxiety Scale scores. The secondary outcome indicators included the Zung Self-rating Depression Scale, the self-rating Anxiety Scale, and the Insomnia Severity Index. Pre- and post-intervention assessments were conducted. The patients\u2019 symptoms related to depression, anxiety, and insomnia were reassessed 4 weeks after the post-intervention evaluation.<\/jats:p>\n          <jats:p>RESULTS<\/jats:p>\n          <jats:p>Patients who underwent the QMT intervention for 4 weeks exhibited a statistically significant reduction in scores on the 17 Hamilton Depression Rating Scale, Hamilton Anxiety Scale, the Zung Self-Rating Depression Scale, the Self-Rating Anxiety Scale, and the Insomnia Severity Index relative to their pre-intervention scores (all P  &lt; 0.05).<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>QMT training for 4 weeks is an effective nonpharmacological treatment for symptoms of depression, anxiety, and insomnia among patients with mild-to-moderate depression.<\/jats:p>","DOI":"10.5498\/wjp.v15.i4.104450","type":"journal-article","created":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T05:13:51Z","timestamp":1742879631000},"source":"Crossref","is-referenced-by-count":0,"title":["Effect of Qi-based mindfulness therapy for mild-to-moderate depression"],"prefix":"10.5498","volume":"15","author":[{"given":"Qiong-Wei","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue-Jiao","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2025,4,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2004.03.003"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1037\/a0020283"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2018.10.006"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32408-5"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1943"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1002\/da.22788"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2023.1034246"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1111\/jonm.13049"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-022-01326-3"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2009.07.007"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1590\/2237-6089-2019-0016"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2018.00866"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2021.110266"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X19666210609162809"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13996"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1186\/s40359-021-00618-2"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-023-05223-8"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-024-05651-0"},{"key":"B19","unstructured":"Chiang HC, Yang ST, Lee KC, Huang PY, Hsu M, Chang HH. 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