{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T00:44:20Z","timestamp":1724978660601},"reference-count":11,"publisher":"Baishideng Publishing Group Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Virol"],"abstract":"BACKGROUND<\/jats:p>\n Varicella (chickenpox) and herpes zoster (shingles) are outcomes of varicella-zoster virus (VZV) infection, and understanding their incidence trends is vital for public health planning.<\/jats:p>\n AIM<\/jats:p>\n To conduct an ambispective epidemiological study by analyzing the main epidemiological characteristics of VZV infection during an 18 year-period (2000-2018).<\/jats:p>\n METHODS<\/jats:p>\n We used descriptive and epidemiological methods to characterize chickenpox in Bulgaria, the city of Plovdiv and the region for a period of 18 years (2000-2018).<\/jats:p>\n RESULTS<\/jats:p>\n The average incidence of varicella-zoster infection for the period 2000\u20132018 in the Plovdiv region was estimated at 449.58\u2030. The highest relative share of the infection was assessed in the month of January at 13.6%, and the lowest in the months of August and September at 2.9% (both months). The age group most affected by the infection was 1-4 years, followed by 5-9 years. This corresponds to the so-called \"pro-epidemic population\" - a phenomenon typical for airborne infections, confirming their mass impact on the perpetuation of VZV infection.<\/jats:p>\n CONCLUSION<\/jats:p>\n Our findings reveal significant insights into VZV epidemiology, including age-specific incidence rates, clinical manifestations, and vaccination impact. This comprehensive analysis contributes to the broader understanding of VZV infection dynamics and may inform evidence-based preventive measures.<\/jats:p>","DOI":"10.5501\/wjv.v13.i3.92525","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T02:18:01Z","timestamp":1724897881000},"source":"Crossref","is-referenced-by-count":0,"title":["Ambispective epidemiological observational study of varicella-zoster virus infection: An 18 year-single-center Bulgarian experience"],"prefix":"10.5501","volume":"13","author":[{"given":"Hristiana M","family":"Batselova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsvetelina V","family":"Velikova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2024,9,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2008.03.011"},{"key":"B2","unstructured":"Order No. 21 of July 18, 2005. On the regulation for registration, communication and reporting of communicable diseases. Available from: https:\/\/www.mh.government.bg\/media\/filer_public\/2015\/04\/17\/naredba-21-ot-2005g-spisak-zarazni-bolesti-red-registratsia.pdf"},{"key":"B3","unstructured":"Varicella vaccination in the European Union. ECDC guidance. Available from: http:\/\/ecdc.europa.eu\/en\/publications\/Publications\/Varicella-Guidance-2015.pdf"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01956-05"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2018.09.013"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2018.1546525"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.10.045"},{"key":"B8","unstructured":"Chapter 22: Varicella; Epidemiology and Prevention of Vaccine. Preventable Dis-eases. CDC. Available from: https:\/\/www.cdc.gov\/vaccines\/pubs\/pinkbook\/downloads\/varicella.pdf"},{"key":"B9","unstructured":"Regulation No. 21 of July 18, 2005 on registration, communication and reporting of communicable diseases effective from January 1, 2006. Issued by the Minister of Health. Available from: https:\/\/lex.bg\/laws\/ldoc\/2135508238"},{"key":"B10","unstructured":"Informing bulletin for VZV infections. National Center for Infectious and Parasitic Diseases. Available from: https:\/\/www.ncipd.org\/index.php?option=com_biuletin&view=view&month=25&year=2024&lang=bg"},{"key":"B11","unstructured":"Internal migration of the Bulgarian citizens. National Statistical Institute. Last access on June 25, 2024. Available from: https:\/\/www.nsi.bg\/bg\/content\/3067\/54-%D0%B2%D1%8A%D1%82%D1%80%D0%B5%D1%88%D0%BD%D0%B0-%D0%BC%D0%B8%D0%B3%D1%80%D0%B0%D1%86%D0%B8%D1%8F-%D0%BD%D0%B0-%D0%BD%D0%B0%D1%81%D0%B5%D0%BB%D0%B5%D0%BD%D0%B8%D0%B5%D1%82%D0%BE-%D0%BC%D0%B5%D0%B6%D0%B4%D1%83-%D1%81%D1%82%D0%B0%D1%82%D0%B8%D1%81%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D1%82%D0%B5-%D1%80%D0%B0%D0%B9%D0%BE%D0%BD%D0%B8-%D0%BF%D0%BE-%D0%BF%D0%BE%D0%BB"}],"container-title":["World Journal of Virology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/2220-3249\/full\/v13\/i3\/92525.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/2220-3249\/full\/v13\/i3\/92525.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T02:18:24Z","timestamp":1724897904000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/2220-3249\/full\/v13\/i3\/92525.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,25]]},"references-count":11,"journal-issue":{"issue":"3"},"alternative-id":["92525"],"URL":"https:\/\/doi.org\/10.5501\/wjv.v13.i3.92525","relation":{},"ISSN":["2220-3249"],"issn-type":[{"value":"2220-3249","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9,25]]}}}