{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T01:28:10Z","timestamp":1782005290860,"version":"3.54.5"},"reference-count":63,"publisher":"Baishideng Publishing Group Inc.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Virol"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>The risk of severe coronavirus disease 2019 (COVID-19) in pregnant women is elevated.<\/jats:p>\n          <jats:p>AIM<\/jats:p>\n          <jats:p>To examine the outcomes of pregnant women with COVID-19 and report perinatal outcomes and complications, while providing a brief review of current literature.<\/jats:p>\n          <jats:p>METHODS<\/jats:p>\n          <jats:p>The study included pregnant women presenting from April 2020 to February 2022 to the emergency department (ED) of a tertiary hospital. We retrospectively recorded the maternal and perinatal files, including patient epidemiological and clinical characteristics, laboratory values, outcomes, treatment modalities and associations were explored.<\/jats:p>\n          <jats:p>RESULTS<\/jats:p>\n          <jats:p>Among the 60 pregnant women, 25% required hospitalization, all of whom were symptomatic. Preterm delivery occurred in 30% of cases. Ten percent of neonates required admission to the neonatal intensive care unit, and 5% were classified as small for their gestational age. All mothers survived COVID-19 and pregnancy, with 6.6% requiring invasive mechanical ventilation. Preterm delivery rates did not differ between hospitalized and non-hospitalized pregnant women; composite unfavorable perinatal outcomes, including stillbirth, small for gestational age, or neonatal intensive care unit (ICU) admission, did not significantly increase in the cases hospitalized for COVID-19 (P  = 0.09). The odds of hospitalization increased 2.3-fold for each day of delayed ED presentation [adj. OR (95%CI: 1.46-3.624), P  &lt; 0.001]. Comorbidity status was an independent predictor of hospitalization, albeit with marginal significance [adj. OR = 16.13 (95%CI: 1.021-255.146), P  = 0.048]. No independent predictors of adverse fetal outcome (composite) were identified, and eventual hospitalization failed to reach statistical significance by a slight margin (P  = 0.054).<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Delayed ED presentation and comorbidities increase hospitalization odds. This study highlights the importance of continuous and specific guidance for managing pregnant COVID-19 patients, including timely and appropriate interventions to minimize maternal and perinatal morbidity and mortality.<\/jats:p>","DOI":"10.5501\/wjv.v13.i4.96573","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T01:19:28Z","timestamp":1729214368000},"source":"Crossref","is-referenced-by-count":1,"title":["COVID-19 in pregnancy: Perinatal outcomes and complications"],"prefix":"10.5501","volume":"13","author":[{"given":"Karolina","family":"Akinosoglou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Schinas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelia","family":"Papageorgiou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodoros","family":"Karampitsakos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasiliki","family":"Dimakopoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni","family":"Polyzou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Argyrios","family":"Tzouvelekis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markos","family":"Marangos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Despoina","family":"Papageorgiou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Spernovasilis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Adonakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2024,12,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6944e3"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2021.2606"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-023-04584-6"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.06.022"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m3320"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14512"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7047e1"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.1190"},{"key":"B9","unstructured":"Pregnancy | COVID-19 Treatment Guidelines. 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