{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T01:44:41Z","timestamp":1766627081570,"version":"3.41.0"},"reference-count":7,"publisher":"Baishideng Publishing Group Inc.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Virol"],"abstract":"<jats:p>This letter evaluates Shahid et al \u2019s study in 2025 on the rising hepatitis A virus (HAV) among adults in Pakistan, highlighting a shift in the virus\u2019s epidemiology. Once primarily a childhood disease in low-income regions, HAV is now increasingly affecting adults, also seen globally due to improved sanitation. The study highlights public health challenges from adult HAV infections, which can lead to complications like coagulopathy and acute liver failure. It also has limitations, including being a single-center study and lacking seroprevalence and socioeconomic data, indicating the need for further research. This letter calls for urgent public health measures to extend adult vaccination programs and improve sanitation to address the increasing HAV infection in adult populations.<\/jats:p>","DOI":"10.5501\/wjv.v14.i2.102519","type":"journal-article","created":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T03:02:34Z","timestamp":1750647754000},"source":"Crossref","is-referenced-by-count":1,"title":["Rising adult hepatitis A in Pakistan: Shifting trends and public health solutions"],"prefix":"10.5501","volume":"14","author":[{"given":"Saad","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulqadir J","family":"Nashwan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2025,6,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.5501\/wjv.v14.i1.97482"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1159\/000252778"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2020.1832408"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.2147\/RMHP.S211170"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.46234\/ccdcw2024.202"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31429"},{"key":"B7","unstructured":"Centers for Disease Control and Prevention.   Viral hepatitis surveillance, United States, 2021. [cited 20 October 2024]. Available from: https:\/\/www.cdc.gov\/hepatitis\/statistics\/2021surveillance\/index.htm"}],"container-title":["World Journal of Virology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/2220-3249\/full\/v14\/i2\/102519.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/2220-3249\/full\/v14\/i2\/102519.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T03:02:51Z","timestamp":1750647771000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/2220-3249\/full\/v14\/i2\/102519.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,25]]},"references-count":7,"journal-issue":{"issue":"2"},"alternative-id":["102519"],"URL":"https:\/\/doi.org\/10.5501\/wjv.v14.i2.102519","relation":{},"ISSN":["2220-3249"],"issn-type":[{"value":"2220-3249","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,25]]}}}