{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T11:27:16Z","timestamp":1786534036362,"version":"build-2736575974"},"reference-count":13,"publisher":"Baishideng Publishing Group Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Nephrol"],"abstract":"<jats:p>I read with interest the retrospective cohort study by Kleinman et al  published in World Journal of Nephrology . Renin-angiotensin-aldosterone system inhibitors (RAASi) anchor therapy for chronic kidney disease, heart failure, and hypertension, but hyperkalemia often curtails optimal use. This letter synthesizes a retrospective cohort of 13447 patiromer users, where approximately 25% high adherers [proportion of days covered (PDC) \u2265 80%] showed approximately 10% greater RAASi utilization (days\u2019 supply and PDC) across angiotensin-converting enzyme inhibitors, angiotensin-receptor blockers, and mineralocorticoid receptor antagonists vs  lower adherers. Findings echo OPAL-HK, reinforce Kidney Disease: Improving Global Outcomes 2021 binder prioritization, and urge adherence strategies to sustain guideline therapy, cut hospitalizations, and integrate with SGLT2i\/finerenone.<\/jats:p>","DOI":"10.5527\/wjn.119286","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T15:37:42Z","timestamp":1780414662000},"source":"Crossref","is-referenced-by-count":0,"title":["Letter to the Editor: Enhancing renin-angiotensin-aldosterone system inhibitors utilization through patiromer adherence - real-world insights for nephrology practice"],"prefix":"10.5527","volume":"15","author":[{"given":"Gemechu Dereje","family":"Feyissa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/s1062-1458(01)00550-5"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011303"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.11.003"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/suy030"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.496"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hft134"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.5527\/wjn.v15.i1.113599"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1410853"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.34067\/KID.0000000000000561"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2019.25.5.588"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2019.18443"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.16290"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0281775"}],"container-title":["World Journal of Nephrology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/2220-6124\/full\/v15\/i3\/119286.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/2220-6124\/full\/v15\/i3\/119286.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T10:27:46Z","timestamp":1786530466000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/2220-6124\/full\/v15\/i3\/119286.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,25]]},"references-count":13,"journal-issue":{"issue":"3"},"alternative-id":["119286"],"URL":"https:\/\/doi.org\/10.5527\/wjn.119286","relation":{},"ISSN":["2220-6124"],"issn-type":[{"value":"2220-6124","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9,25]]}}}