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Periostin, a cellular matrix protein, plays a key role in modulating extracellular interactions. Increased periostin expression in tissue, serum, and urine correlates with type 2 diabetes, making it a valuable biomarker alongside neutrophil gelatinase-associated lipocalin and kidney injury molecule-1. While periostin and neutrophil gelatinase-associated lipocalin reflect distal tubular damage, kidney injury molecule-1 serves as a marker for proximal tubular injury. Combining these biomarkers enhances diagnostic precision.<\/jats:p>","DOI":"10.5527\/wjn.v14.i4.103649","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T07:59:10Z","timestamp":1766390350000},"source":"Crossref","is-referenced-by-count":0,"title":["Predictive value of biomarkers for tubulointerstitial and glomerular interactions in diabetic nephropathy"],"prefix":"10.5527","volume":"14","author":[{"given":"Mario","family":"Alamilla-Sanchez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin B","family":"Yama Estrella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique F","family":"Morales L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Delgado Pineda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2025,12,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.5527\/wjn.v13.i4.98880"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.kisu.2017.10.003"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3390\/ijms251810222"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2024.2398188"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/3102962"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2005.09915.x"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2005070757"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1085605"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfx321"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1172\/JCI129937"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2006040407"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2013070810"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00958.x"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2008.01.020"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.4103\/ijmr.IJMR_455_21"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1159\/000507858"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2002.00433.x"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.3109\/00365513.2011.645055"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7659243"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2014.04.007"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr670"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0124055"}],"container-title":["World Journal of Nephrology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/2220-6124\/full\/v14\/i4\/103649.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/2220-6124\/full\/v14\/i4\/103649.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T07:59:11Z","timestamp":1766390351000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/2220-6124\/full\/v14\/i4\/103649.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,25]]},"references-count":22,"journal-issue":{"issue":"4"},"alternative-id":["103649"],"URL":"https:\/\/doi.org\/10.5527\/wjn.v14.i4.103649","relation":{},"ISSN":["2220-6124"],"issn-type":[{"value":"2220-6124","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,25]]}}}