{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:04:05Z","timestamp":1792073045638,"version":"4.4.0"},"reference-count":150,"publisher":"XMLink","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["wjmh.org"],"crossmark-restriction":false},"short-container-title":["World J Mens Health"],"published-print":{"date-parts":[[2022]]},"DOI":"10.5534\/wjmh.210001","type":"journal-article","created":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T08:25:16Z","timestamp":1615883116000},"page":"11","update-policy":"https:\/\/doi.org\/10.5534\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["The Effect of Metformin on Male Reproductive Function and Prostate: An Updated Review"],"prefix":"10.5534","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9545-7123","authenticated-orcid":false,"given":"Chin-Hsiao","family":"Tseng","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan."},{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan."},{"name":"Division of Environmental Health and Occupational Medicine of the National Health Research Institutes, Zhunan, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.5534\/wjmh.210001_ref1","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.2337\/dc12-0413","volume":"35","author":"Inzucchi","year":"2012","journal-title":"Diabetes Care"},{"key":"10.5534\/wjmh.210001_ref2","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/j.tips.2020.09.001","volume":"41","author":"He","year":"2020","journal-title":"Trends Pharmacol Sci"},{"key":"10.5534\/wjmh.210001_ref3","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.phrs.2016.12.003","volume":"117","author":"Maniar","year":"2017","journal-title":"Pharmacol Res"},{"key":"10.5534\/wjmh.210001_ref4","doi-asserted-by":"crossref","first-page":"7330","DOI":"10.1021\/acs.jmedchem.8b00906","volume":"61","author":"Chen","year":"2018","journal-title":"J Med Chem"},{"key":"10.5534\/wjmh.210001_ref5","doi-asserted-by":"crossref","first-page":"e008860","DOI":"10.1161\/JAHA.118.008860","volume":"7","author":"Tseng","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"10.5534\/wjmh.210001_ref6","doi-asserted-by":"crossref","first-page":"e011640","DOI":"10.1161\/JAHA.118.011640","volume":"8","author":"Tseng","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"10.5534\/wjmh.210001_ref7","doi-asserted-by":"crossref","first-page":"592901","DOI":"10.3389\/fmed.2020.592901","volume":"7","author":"Tseng","year":"2021","journal-title":"Front Med"},{"key":"10.5534\/wjmh.210001_ref8","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.diabet.2018.05.001","volume":"45","author":"Tseng","year":"2019","journal-title":"Diabetes Metab"},{"key":"10.5534\/wjmh.210001_ref9","doi-asserted-by":"crossref","first-page":"e3206","DOI":"10.1002\/dmrr.3206","volume":"36","author":"Tseng","year":"2020","journal-title":"Diabetes Metab Res Rev"},{"key":"10.5534\/wjmh.210001_ref10","doi-asserted-by":"crossref","first-page":"578831","DOI":"10.3389\/fphar.2020.578831","volume":"11","author":"Tseng","year":"2021","journal-title":"Front Pharmacol"},{"key":"10.5534\/wjmh.210001_ref11","doi-asserted-by":"crossref","first-page":"37","DOI":"10.14336\/AD.2017.1202","volume":"10","author":"Tseng","year":"2019","journal-title":"Aging Dis"},{"key":"10.5534\/wjmh.210001_ref12","doi-asserted-by":"crossref","first-page":"658","DOI":"10.14336\/AD.2019.0621","volume":"11","author":"Tseng","year":"2020","journal-title":"Aging Dis"},{"key":"10.5534\/wjmh.210001_ref13","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1530\/EJE-19-0133","volume":"180","author":"Tseng","year":"2019","journal-title":"Eur J Endocrinol"},{"key":"10.5534\/wjmh.210001_ref14","doi-asserted-by":"crossref","first-page":"2042018819895159","DOI":"10.1177\/2042018819895159","volume":"10","author":"Tseng","year":"2019","journal-title":"Ther Adv Endocrinol Metab"},{"key":"10.5534\/wjmh.210001_ref15","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1530\/EJE-20-0507","volume":"184","author":"Tseng","year":"2021","journal-title":"Eur J Endocrinol"},{"key":"10.5534\/wjmh.210001_ref16","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1093\/ecco-jcc\/jjaa136","volume":"15","author":"Tseng","year":"2021","journal-title":"J Crohns Colitis"},{"key":"10.5534\/wjmh.210001_ref17","first-page":"55","volume":"2","author":"Bertoldo","year":"2014","journal-title":"Ann Transl Med"},{"key":"10.5534\/wjmh.210001_ref18","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/CEJ.0000000000000394","volume":"27","author":"Nguyen","year":"2018","journal-title":"Eur J Cancer Prev"},{"key":"10.5534\/wjmh.210001_ref19","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1097\/FPC.0b013e32833fe789","volume":"20","author":"Chen","year":"2010","journal-title":"Pharmacogenet Genomics"},{"key":"10.5534\/wjmh.210001_ref20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15171\/apb.2019.001","volume":"9","author":"El-Arabey","year":"2019","journal-title":"Adv Pharm Bull"},{"key":"10.5534\/wjmh.210001_ref21","doi-asserted-by":"crossref","first-page":"5619","DOI":"10.18632\/oncotarget.13639","volume":"8","author":"Yu","year":"2017","journal-title":"Oncotarget"},{"key":"10.5534\/wjmh.210001_ref22","doi-asserted-by":"crossref","first-page":"675","DOI":"10.3389\/fendo.2018.00675","volume":"9","author":"Faure","year":"2018","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.5534\/wjmh.210001_ref23","first-page":"158","volume":"9","author":"Alzain","year":"2020","journal-title":"Int J Pharm Res Allied Sci"},{"key":"10.5534\/wjmh.210001_ref24","doi-asserted-by":"crossref","first-page":"3621","DOI":"10.2174\/1381612821666150710150041","volume":"21","author":"Ferreira","year":"2015","journal-title":"Curr Pharm Des"},{"key":"10.5534\/wjmh.210001_ref25","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1111\/jsm.12245","volume":"10","author":"Labazi","year":"2013","journal-title":"J Sex Med"},{"key":"10.5534\/wjmh.210001_ref26","doi-asserted-by":"crossref","first-page":"423.e1","DOI":"10.1016\/j.urology.2015.04.035","volume":"86","author":"Silva","year":"2015","journal-title":"Urology"},{"key":"10.5534\/wjmh.210001_ref27","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.esxm.2020.01.006","volume":"8","author":"Zhang","year":"2020","journal-title":"Sex Med"},{"key":"10.5534\/wjmh.210001_ref28","doi-asserted-by":"crossref","first-page":"355","DOI":"10.21037\/tau.2020.02.07","volume":"9","author":"Zhang","year":"2020","journal-title":"Transl Androl Urol"},{"key":"10.5534\/wjmh.210001_ref29","doi-asserted-by":"crossref","first-page":"608","DOI":"10.2164\/jandrol.111.013714","volume":"33","author":"Rey-Valzacchi","year":"2012","journal-title":"J Androl"},{"key":"10.5534\/wjmh.210001_ref30","doi-asserted-by":"crossref","first-page":"556","DOI":"10.21037\/tau.2017.03.52","volume":"6","author":"Patel","year":"2017","journal-title":"Transl Androl Urol"},{"key":"10.5534\/wjmh.210001_ref31","doi-asserted-by":"crossref","first-page":"3237","DOI":"10.1042\/CS20201023","volume":"134","author":"Navaneethabalakrishnan","year":"2020","journal-title":"Clin Sci (Lond)"},{"key":"10.5534\/wjmh.210001_ref32","first-page":"FC21","volume":"10","author":"Al-Kuraishy","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"10.5534\/wjmh.210001_ref33","first-page":"43","volume":"10","author":"Abdul-Hadi","year":"2020","journal-title":"Int J Nutr Pharmacol Neurol Dis"},{"key":"10.5534\/wjmh.210001_ref34","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.2047-2927.2012.00048.x","volume":"1","author":"Alberti","year":"2013","journal-title":"Andrology"},{"key":"10.5534\/wjmh.210001_ref35","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.amjmed.2019.08.052","volume":"133","author":"Tanaka","year":"2020","journal-title":"Am J Med"},{"key":"10.5534\/wjmh.210001_ref36","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/1479972315619382","volume":"13","author":"Turan","year":"2016","journal-title":"Chron Respir Dis"},{"key":"10.5534\/wjmh.210001_ref37","doi-asserted-by":"crossref","first-page":"24","DOI":"10.14712\/23362936.2015.42","volume":"116","author":"Dursun","year":"2015","journal-title":"Prague Med Rep"},{"key":"10.5534\/wjmh.210001_ref38","doi-asserted-by":"crossref","first-page":"e990","DOI":"10.1097\/MD.0000000000000990","volume":"94","author":"Yang","year":"2015","journal-title":"Medicine (Baltimore)"},{"key":"10.5534\/wjmh.210001_ref39","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1093\/ibd\/izy401","volume":"25","author":"Shmidt","year":"2019","journal-title":"Inflamm Bowel Dis"},{"key":"10.5534\/wjmh.210001_ref40","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1111\/j.1743-6109.2012.02736.x","volume":"9","author":"Keller","year":"2012","journal-title":"J Sex Med"},{"key":"10.5534\/wjmh.210001_ref41","doi-asserted-by":"crossref","first-page":"138","DOI":"10.5534\/wjmh.180026","volume":"37","author":"Moon","year":"2019","journal-title":"World J Mens Health"},{"key":"10.5534\/wjmh.210001_ref42","doi-asserted-by":"crossref","first-page":"e0207947","DOI":"10.1371\/journal.pone.0207947","volume":"13","author":"Solym\u00e1r","year":"2018","journal-title":"PLoS One"},{"key":"10.5534\/wjmh.210001_ref43","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.sxmr.2018.11.007","volume":"7","author":"Munk","year":"2019","journal-title":"Sex Med Rev"},{"key":"10.5534\/wjmh.210001_ref44","doi-asserted-by":"crossref","first-page":"3304","DOI":"10.1093\/humrep\/des264","volume":"27","author":"Tartarin","year":"2012","journal-title":"Hum Reprod"},{"key":"10.5534\/wjmh.210001_ref45","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1900\/RDS.2016.13.59","volume":"13","author":"Tertti","year":"2016","journal-title":"Rev Diabet Stud"},{"key":"10.5534\/wjmh.210001_ref46","first-page":"417","volume":"6","author":"Naglaa","year":"2010","journal-title":"J Am Sci"},{"key":"10.5534\/wjmh.210001_ref47","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/andr.12567","volume":"7","author":"Nna","year":"2019","journal-title":"Andrology"},{"key":"10.5534\/wjmh.210001_ref48","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1080\/13813455.2018.1543329","volume":"126","author":"Nna","year":"2020","journal-title":"Arch Physiol Biochem"},{"key":"10.5534\/wjmh.210001_ref49","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1111\/andr.12739","volume":"8","author":"Nna","year":"2020","journal-title":"Andrology"},{"key":"10.5534\/wjmh.210001_ref50","first-page":"1013","volume":"11","author":"Nasrolahi","year":"2013","journal-title":"Iran J Reprod Med"},{"key":"10.5534\/wjmh.210001_ref51","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1134\/S0012496620040031","volume":"493","author":"Derkach","year":"2020","journal-title":"Dokl Biol Sci"},{"key":"10.5534\/wjmh.210001_ref52","doi-asserted-by":"crossref","first-page":"e13816","DOI":"10.1111\/and.13816","volume":"52","author":"Derkach","year":"2020","journal-title":"Andrologia"},{"key":"10.5534\/wjmh.210001_ref53","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1016\/j.fertnstert.2010.12.009","volume":"95","author":"Morgante","year":"2011","journal-title":"Fertil Steril"},{"key":"10.5534\/wjmh.210001_ref54","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.cbi.2009.03.001","volume":"180","author":"Attia","year":"2009","journal-title":"Chem Biol Interact"},{"key":"10.5534\/wjmh.210001_ref55","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/bph.12522","volume":"171","author":"Alves","year":"2014","journal-title":"Br J Pharmacol"},{"key":"10.5534\/wjmh.210001_ref56","doi-asserted-by":"crossref","first-page":"e38840","DOI":"10.1371\/journal.pone.0038840","volume":"7","author":"Hurtado de Llera","year":"2012","journal-title":"PLoS One"},{"key":"10.5534\/wjmh.210001_ref57","doi-asserted-by":"crossref","first-page":"287","DOI":"10.3390\/ani10020287","volume":"10","author":"Grandhaye","year":"2020","journal-title":"Animals (Basel)"},{"key":"10.5534\/wjmh.210001_ref58","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1590\/S0102-865020160060000008","volume":"31","author":"Asghari","year":"2016","journal-title":"Acta Cir Bras"},{"key":"10.5534\/wjmh.210001_ref59","author":"Ghasemnejad-Berenji","year":"2018","journal-title":"Andrologia"},{"key":"10.5534\/wjmh.210001_ref60","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1007\/s10815-015-0506-2","volume":"32","author":"Yan","year":"2015","journal-title":"J Assist Reprod Genet"},{"key":"10.5534\/wjmh.210001_ref61","first-page":"9151067","volume":"2019","author":"Ye","year":"2019","journal-title":"Oxid Med Cell Longev"},{"key":"10.5534\/wjmh.210001_ref62","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.3390\/nu12071932","volume":"12","author":"Liu","year":"2020","journal-title":"Nutrients"},{"key":"10.5534\/wjmh.210001_ref63","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.cryobiol.2014.10.008","volume":"69","author":"C\u00f3rdova","year":"2014","journal-title":"Cryobiology"},{"key":"10.5534\/wjmh.210001_ref64","first-page":"295","volume":"13","author":"Raghif","year":"2015","journal-title":"Iraqi JMS"},{"key":"10.5534\/wjmh.210001_ref65","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.aju.2017.10.002","volume":"16","author":"Dabbous","year":"2017","journal-title":"Arab J Urol"},{"key":"10.5534\/wjmh.210001_ref66","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.3892\/ol.2014.1936","volume":"7","author":"Iguchi","year":"2014","journal-title":"Oncol Lett"},{"key":"10.5534\/wjmh.210001_ref67","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1002\/pros.23522","volume":"78","author":"Kranzb\u00fchler","year":"2018","journal-title":"Prostate"},{"key":"10.5534\/wjmh.210001_ref68","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.canlet.2014.09.001","volume":"354","author":"Lee","year":"2014","journal-title":"Cancer Lett"},{"key":"10.5534\/wjmh.210001_ref69","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1158\/1541-7786.MCR-16-0493","volume":"15","author":"Sarmento-Cabral","year":"2017","journal-title":"Mol Cancer Res"},{"key":"10.5534\/wjmh.210001_ref70","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1002\/pros.23228","volume":"76","author":"Jayalath","year":"2016","journal-title":"Prostate"},{"key":"10.5534\/wjmh.210001_ref71","doi-asserted-by":"crossref","first-page":"e9427","DOI":"10.1097\/MD.0000000000009427","volume":"96","author":"Park","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"10.5534\/wjmh.210001_ref72","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.diabres.2018.04.022","volume":"141","author":"Chen","year":"2018","journal-title":"Diabetes Res Clin Pract"},{"key":"10.5534\/wjmh.210001_ref73","doi-asserted-by":"crossref","first-page":"e1914689","DOI":"10.1001\/jamanetworkopen.2019.14689","volume":"2","author":"Beckmann","year":"2019","journal-title":"JAMA Netw Open"},{"key":"10.5534\/wjmh.210001_ref74","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1007\/s10552-013-0257-2","volume":"24","author":"Sanderson","year":"2013","journal-title":"Cancer Causes Control"},{"key":"10.5534\/wjmh.210001_ref75","doi-asserted-by":"crossref","first-page":"73","DOI":"10.4236\/jct.2017.82007","volume":"8","author":"Liu","year":"2017","journal-title":"J Cancer Ther"},{"key":"10.5534\/wjmh.210001_ref76","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.eururo.2013.12.057","volume":"66","author":"Rothermundt","year":"2014","journal-title":"Eur Urol"},{"key":"10.5534\/wjmh.210001_ref77","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1038\/pcan.2014.20","volume":"17","author":"Joshua","year":"2014","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"10.5534\/wjmh.210001_ref78","doi-asserted-by":"crossref","first-page":"227","DOI":"10.4081\/aiua.2018.4.227","volume":"90","author":"Magri","year":"2019","journal-title":"Arch Ital Urol Androl"},{"key":"10.5534\/wjmh.210001_ref79","doi-asserted-by":"crossref","first-page":"504","DOI":"10.3389\/fphar.2020.00504","volume":"11","author":"Xiong","year":"2020","journal-title":"Front Pharmacol"},{"key":"10.5534\/wjmh.210001_ref80","doi-asserted-by":"crossref","first-page":"4309","DOI":"10.1158\/1078-0432.CCR-18-0106","volume":"24","author":"Hayashi","year":"2018","journal-title":"Clin Cancer Res"},{"key":"10.5534\/wjmh.210001_ref81","first-page":"E568","volume":"14","author":"Aglamis","year":"2020","journal-title":"Can Urol Assoc J"},{"key":"10.5534\/wjmh.210001_ref82","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.3390\/nu12092648","volume":"12","author":"Crocetto","year":"2020","journal-title":"Nutrients"},{"key":"10.5534\/wjmh.210001_ref83","doi-asserted-by":"crossref","first-page":"e0173335","DOI":"10.1371\/journal.pone.0173335","volume":"12","author":"Wang","year":"2017","journal-title":"PLoS One"},{"key":"10.5534\/wjmh.210001_ref84","doi-asserted-by":"crossref","first-page":"F407","DOI":"10.1152\/ajprenal.00443.2017","volume":"314","author":"Wang","year":"2018","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.5534\/wjmh.210001_ref85","doi-asserted-by":"crossref","first-page":"15639","DOI":"10.1038\/srep15639","volume":"5","author":"Mosli","year":"2015","journal-title":"Sci Rep"},{"key":"10.5534\/wjmh.210001_ref86","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/s11255-018-1826-9","volume":"50","author":"Xu","year":"2018","journal-title":"Int Urol Nephrol"},{"key":"10.5534\/wjmh.210001_ref87","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1089\/jomh.2014.0051","volume":"11","author":"Murff","year":"2014","journal-title":"J Mens Health"},{"key":"10.5534\/wjmh.210001_ref88","doi-asserted-by":"crossref","first-page":"e0219394","DOI":"10.1371\/journal.pone.0219394","volume":"14","author":"Hong","year":"2019","journal-title":"PLoS One"},{"issue":"7-8 Suppl 5","key":"10.5534\/wjmh.210001_ref89","doi-asserted-by":"crossref","first-page":"S159","DOI":"10.5489\/cuaj.2314","volume":"8","author":"Fleshner","year":"2014","journal-title":"Can Urol Assoc J"},{"key":"10.5534\/wjmh.210001_ref90","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.1007\/s00345-020-03084-4","volume":"38","author":"Wu","year":"2020","journal-title":"World J Urol"},{"key":"10.5534\/wjmh.210001_ref91","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/pros.23451","volume":"78","author":"Shih","year":"2018","journal-title":"Prostate"},{"key":"10.5534\/wjmh.210001_ref92","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1159\/000448484","volume":"97","author":"Fu","year":"2016","journal-title":"Urol Int"},{"key":"10.5534\/wjmh.210001_ref93","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1159\/000052430","volume":"39","author":"Hammarsten","year":"2001","journal-title":"Eur Urol"},{"key":"10.5534\/wjmh.210001_ref94","doi-asserted-by":"crossref","first-page":"507","DOI":"10.3390\/biomedicines8110507","volume":"8","author":"Franko","year":"2020","journal-title":"Biomedicines"},{"key":"10.5534\/wjmh.210001_ref95","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1158\/1940-6207.CAPR-15-0014","volume":"8","author":"Saha","year":"2015","journal-title":"Cancer Prev Res (Phila)"},{"key":"10.5534\/wjmh.210001_ref96","doi-asserted-by":"crossref","first-page":"3576","DOI":"10.1038\/sj.onc.1211024","volume":"27","author":"Ben Sahra","year":"2008","journal-title":"Oncogene"},{"key":"10.5534\/wjmh.210001_ref97","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.3892\/ijmm.2014.1707","volume":"33","author":"Wang","year":"2014","journal-title":"Int J Mol Med"},{"key":"10.5534\/wjmh.210001_ref98","doi-asserted-by":"crossref","first-page":"5622","DOI":"10.1158\/1078-0432.CCR-18-0420","volume":"24","author":"Liu","year":"2018","journal-title":"Clin Cancer Res"},{"key":"10.5534\/wjmh.210001_ref99","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1080\/15384047.2016.1156273","volume":"17","author":"Chen","year":"2016","journal-title":"Cancer Biol Ther"},{"key":"10.5534\/wjmh.210001_ref100","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1158\/1535-7163.MCT-19-0874","volume":"19","author":"Kong","year":"2020","journal-title":"Mol Cancer Ther"},{"key":"10.5534\/wjmh.210001_ref101","doi-asserted-by":"crossref","first-page":"2823","DOI":"10.1093\/carcin\/bgt307","volume":"34","author":"Akinyeke","year":"2013","journal-title":"Carcinogenesis"},{"key":"10.5534\/wjmh.210001_ref102","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/s41391-018-0085-2","volume":"22","author":"Zaidi","year":"2019","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"10.5534\/wjmh.210001_ref103","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.3390\/cancers11081153","volume":"11","author":"Hayashi","year":"2019","journal-title":"Cancers (Basel)"},{"key":"10.5534\/wjmh.210001_ref104","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.3390\/jcm9082680","volume":"9","author":"Hatano","year":"2020","journal-title":"J Clin Med"},{"key":"10.5534\/wjmh.210001_ref105","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1158\/0008-5472.CAN-09-2782","volume":"70","author":"Ben Sahra","year":"2010","journal-title":"Cancer Res"},{"key":"10.5534\/wjmh.210001_ref106","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.1158\/1535-7163.MCT-14-0451","volume":"13","author":"Babcook","year":"2014","journal-title":"Mol Cancer Ther"},{"key":"10.5534\/wjmh.210001_ref107","doi-asserted-by":"crossref","first-page":"e1536","DOI":"10.1038\/cddis.2014.500","volume":"5","author":"Babcook","year":"2014","journal-title":"Cell Death Dis"},{"key":"10.5534\/wjmh.210001_ref108","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.1158\/0008-5472.CAN-10-3471","volume":"71","author":"Iliopoulos","year":"2011","journal-title":"Cancer Res"},{"key":"10.5534\/wjmh.210001_ref109","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1074\/jbc.M114.596817","volume":"290","author":"Shao","year":"2015","journal-title":"J Biol Chem"},{"key":"10.5534\/wjmh.210001_ref110","doi-asserted-by":"crossref","first-page":"368","DOI":"10.2174\/1568009618666180724111604","volume":"19","author":"Tran","year":"2019","journal-title":"Curr Cancer Drug Targets"},{"key":"10.5534\/wjmh.210001_ref111","doi-asserted-by":"crossref","first-page":"3891","DOI":"10.2337\/db13-1169","volume":"63","author":"Nomiyama","year":"2014","journal-title":"Diabetes"},{"key":"10.5534\/wjmh.210001_ref112","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1042\/BJ20150122","volume":"469","author":"O'Brien","year":"2015","journal-title":"Biochem J"},{"key":"10.5534\/wjmh.210001_ref113","doi-asserted-by":"crossref","first-page":"36721","DOI":"10.1038\/srep36721","volume":"6","author":"Xiang","year":"2016","journal-title":"Sci Rep"},{"issue":"14 Suppl","key":"10.5534\/wjmh.210001_ref114","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1158\/1538-7445.AM2016-272","volume":"76","author":"Xie","year":"2016","journal-title":"Cancer Res"},{"key":"10.5534\/wjmh.210001_ref115","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1667\/RR13561.1","volume":"181","author":"Zhang","year":"2014","journal-title":"Radiat Res"},{"key":"10.5534\/wjmh.210001_ref116","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1007\/s11255-014-0823-x","volume":"46","author":"Xu","year":"2014","journal-title":"Int Urol Nephrol"},{"key":"10.5534\/wjmh.210001_ref117","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.canlet.2016.12.031","volume":"389","author":"Tong","year":"2017","journal-title":"Cancer Lett"},{"key":"10.5534\/wjmh.210001_ref118","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1186\/s12889-015-2260-x","volume":"15","author":"Blanc-Lapierre","year":"2015","journal-title":"BMC Public Health"},{"key":"10.5534\/wjmh.210001_ref119","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.clgc.2013.04.009","volume":"11","author":"Conteduca","year":"2013","journal-title":"Clin Genitourin Cancer"},{"key":"10.5534\/wjmh.210001_ref120","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1186\/s12885-020-07036-4","volume":"20","author":"Lin","year":"2020","journal-title":"BMC Cancer"},{"key":"10.5534\/wjmh.210001_ref121","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1158\/1055-9965.EPI-06-0410","volume":"15","author":"Kasper","year":"2006","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.5534\/wjmh.210001_ref122","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1158\/1055-9965.EPI-12-1046","volume":"22","author":"Fall","year":"2013","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.5534\/wjmh.210001_ref123","doi-asserted-by":"crossref","first-page":"616","DOI":"10.2337\/dc10-1640","volume":"34","author":"Tseng","year":"2011","journal-title":"Diabetes Care"},{"key":"10.5534\/wjmh.210001_ref124","doi-asserted-by":"crossref","first-page":"142","DOI":"10.3109\/07853890.2010.530683","volume":"43","author":"Tseng","year":"2011","journal-title":"Ann Med"},{"key":"10.5534\/wjmh.210001_ref125","doi-asserted-by":"crossref","first-page":"4097","DOI":"10.7314\/APJCP.2012.13.8.4097","volume":"13","author":"Long","year":"2012","journal-title":"Asian Pac J Cancer Prev"},{"key":"10.5534\/wjmh.210001_ref126","doi-asserted-by":"crossref","first-page":"2831","DOI":"10.1016\/j.ejca.2014.08.007","volume":"50","author":"Tseng","year":"2014","journal-title":"Eur J Cancer"},{"key":"10.5534\/wjmh.210001_ref127","doi-asserted-by":"crossref","first-page":"2514","DOI":"10.1002\/cam4.2025","volume":"8","author":"Kuo","year":"2019","journal-title":"Cancer Med"},{"key":"10.5534\/wjmh.210001_ref128","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1016\/j.eururo.2014.04.027","volume":"66","author":"Preston","year":"2014","journal-title":"Eur Urol"},{"key":"10.5534\/wjmh.210001_ref129","doi-asserted-by":"crossref","first-page":"e116327","DOI":"10.1371\/journal.pone.0116327","volume":"9","author":"Yu","year":"2014","journal-title":"PLoS One"},{"key":"10.5534\/wjmh.210001_ref130","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1097\/CEJ.0000000000000514","volume":"29","author":"Wang","year":"2020","journal-title":"Eur J Cancer Prev"},{"key":"10.5534\/wjmh.210001_ref131","doi-asserted-by":"crossref","first-page":"4507","DOI":"10.3390\/ijms21124507","volume":"21","author":"Shorning","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.5534\/wjmh.210001_ref132","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.3390\/cells9112342","volume":"9","author":"Turnham","year":"2020","journal-title":"Cells"},{"key":"10.5534\/wjmh.210001_ref133","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3389\/fnut.2020.00081","volume":"7","author":"Venniyoor","year":"2020","journal-title":"Front Nutr"},{"key":"10.5534\/wjmh.210001_ref134","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.2337\/dc11-1829","volume":"35","author":"Lehman","year":"2012","journal-title":"Diabetes Care"},{"key":"10.5534\/wjmh.210001_ref135","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1158\/1940-6207.CAPR-15-0425","volume":"9","author":"Wang","year":"2016","journal-title":"Cancer Prev Res (Phila)"},{"key":"10.5534\/wjmh.210001_ref136","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1007\/s10552-018-1087-z","volume":"29","author":"Khan","year":"2018","journal-title":"Cancer Causes Control"},{"key":"10.5534\/wjmh.210001_ref137","doi-asserted-by":"crossref","first-page":"e323","DOI":"10.1016\/j.clgc.2018.12.009","volume":"17","author":"Mark","year":"2019","journal-title":"Clin Genitourin Cancer"},{"key":"10.5534\/wjmh.210001_ref138","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.amjms.2016.01.013","volume":"351","author":"Chong","year":"2016","journal-title":"Am J Med Sci"},{"key":"10.5534\/wjmh.210001_ref139","doi-asserted-by":"crossref","first-page":"3069","DOI":"10.1200\/JCO.2012.46.7043","volume":"31","author":"Margel","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.5534\/wjmh.210001_ref140","first-page":"9509","volume":"25","author":"Taussky","year":"2018","journal-title":"Can J Urol"},{"key":"10.5534\/wjmh.210001_ref141","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/pcan.2014.52","volume":"18","author":"Raval","year":"2015","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"10.5534\/wjmh.210001_ref142","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s10552-015-0687-0","volume":"27","author":"Stopsack","year":"2016","journal-title":"Cancer Causes Control"},{"key":"10.5534\/wjmh.210001_ref143","author":"Roy","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"10.5534\/wjmh.210001_ref144","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.euf.2018.04.001","volume":"5","author":"Campi","year":"2019","journal-title":"Eur Urol Focus"},{"key":"10.5534\/wjmh.210001_ref145","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1093\/annonc\/mdw410","volume":"27","author":"Coyle","year":"2016","journal-title":"Ann Oncol"},{"key":"10.5534\/wjmh.210001_ref146","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00280-016-3037-3","volume":"78","author":"Zhang","year":"2016","journal-title":"Cancer Chemother Pharmacol"},{"key":"10.5534\/wjmh.210001_ref147","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.3390\/cells9112420","volume":"9","author":"Santin","year":"2020","journal-title":"Cells"},{"key":"10.5534\/wjmh.210001_ref148","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1111\/acel.12075","volume":"12","author":"Moiseeva","year":"2013","journal-title":"Aging Cell"},{"key":"10.5534\/wjmh.210001_ref149","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/s41574-020-0335-y","volume":"16","author":"Khosla","year":"2020","journal-title":"Nat Rev Endocrinol"},{"key":"10.5534\/wjmh.210001_ref150","doi-asserted-by":"crossref","first-page":"3993","DOI":"10.18632\/aging.102787","volume":"12","author":"Chen","year":"2020","journal-title":"Aging (Albany NY)"}],"container-title":["The World Journal of Men's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/wjmh.org\/pdf\/10.5534\/wjmh.210001","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.210001","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.210001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T16:29:06Z","timestamp":1671640146000},"score":1,"resource":{"primary":{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.210001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":150,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.5534\/wjmh.210001","relation":{},"ISSN":["2287-4208","2287-4690"],"issn-type":[{"value":"2287-4208","type":"print"},{"value":"2287-4690","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]},"assertion":[{"value":"2021-01-11","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-18","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-22","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-09","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2022 Korean Society for Sexual Medicine and Andrology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}