{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T23:33:11Z","timestamp":1790119991438,"version":"4.0.1"},"reference-count":30,"publisher":"XMLink","issue":"4","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100004329","name":"Javna Agencija za Raziskovalno Dejavnost RS","doi-asserted-by":"publisher","award":["P3\u20130326"],"award-info":[{"award-number":["P3\u20130326"]}],"id":[{"id":"10.13039\/501100004329","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["wjmh.org"],"crossmark-restriction":false},"short-container-title":["World J Mens Health"],"published-print":{"date-parts":[[2025]]},"DOI":"10.5534\/wjmh.240149","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T01:31:03Z","timestamp":1736213463000},"page":"908","update-policy":"https:\/\/doi.org\/10.5534\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Genetic Testing for Monogenic Forms of Male Infertility Contributes to the Clinical Diagnosis of Men with Severe Idiopathic Male Infertility"],"prefix":"10.5534","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5679-0499","authenticated-orcid":false,"given":"Rebeka","family":"Podgrajsek","sequence":"first","affiliation":[{"name":"Department of Human Reproduction, Division of Obstetrics and Gynecology, University Medical Centre Ljubljana, Ljubljana, Slovenia."},{"name":"Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7874-6430","authenticated-orcid":false,"given":"Alenka","family":"Hodzic","sequence":"additional","affiliation":[{"name":"Clinical Institute of Genomic Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia."},{"name":"Faculty of Health Sciences, University of Novo mesto, Novo mesto, Slovenia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9826-0534","authenticated-orcid":false,"given":"Ales","family":"Maver","sequence":"additional","affiliation":[{"name":"Clinical Institute of Genomic Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6495-4845","authenticated-orcid":false,"given":"Martin","family":"Stimpfel","sequence":"additional","affiliation":[{"name":"Department of Human Reproduction, Division of Obstetrics and Gynecology, University Medical Centre Ljubljana, Ljubljana, Slovenia."},{"name":"Institute of Histology and Embryology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1978-8136","authenticated-orcid":false,"given":"Aleksander","family":"Andjelic","sequence":"additional","affiliation":[{"name":"Department of Human Reproduction, Division of Obstetrics and Gynecology, University Medical Centre Ljubljana, Ljubljana, Slovenia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0446-9466","authenticated-orcid":false,"given":"Olivera","family":"Miljanovic","sequence":"additional","affiliation":[{"name":"Center of Medical Genetics and Immunology, Clinical Center of Montenegro, Podgorica, Montenegro."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6522-8775","authenticated-orcid":false,"given":"Momcilo","family":"Ristanovic","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics, Medical Faculty, University of Belgrade, Belgrade, Serbia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0202-0673","authenticated-orcid":false,"given":"Ivana","family":"Novakovic","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics, Medical Faculty, University of Belgrade, Belgrade, Serbia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8877-2416","authenticated-orcid":false,"given":"Dijana","family":"Plaseska-Karanfilska","sequence":"additional","affiliation":[{"name":"Research Centre for Genetic Engineering and Biotechnology \u201cGeorgi D. Efremov\u201d Macedonian Academy of Sciences and Arts, Skopje, Macedonia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3882-9821","authenticated-orcid":false,"given":"Predrag","family":"Noveski","sequence":"additional","affiliation":[{"name":"Research Centre for Genetic Engineering and Biotechnology \u201cGeorgi D. Efremov\u201d Macedonian Academy of Sciences and Arts, Skopje, Macedonia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7134-4335","authenticated-orcid":false,"given":"Sasa","family":"Ostojic","sequence":"additional","affiliation":[{"name":"Centre for Genetic Education, Faculty of Medicine, University of Rijeka, Rijeka, Croatia."},{"name":"Department of Medical Biology and Genetics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4557-3879","authenticated-orcid":false,"given":"Antun","family":"Grskovic","sequence":"additional","affiliation":[{"name":"Department of Urology, Clinical Hospital Center Rijeka, Rijeka, Croatia."},{"name":"Department of Urology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9840-1245","authenticated-orcid":false,"given":"Alena","family":"Buretic-Tomljanovic","sequence":"additional","affiliation":[{"name":"Centre for Genetic Education, Faculty of Medicine, University of Rijeka, Rijeka, Croatia."},{"name":"Department of Medical Biology and Genetics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7824-4978","authenticated-orcid":false,"given":"Borut","family":"Peterlin","sequence":"additional","affiliation":[{"name":"Clinical Institute of Genomic Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia."},{"name":"Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.5534\/wjmh.240149_ref1","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.fertnstert.2017.06.005","volume":"108","author":"Zegers-Hochschild","year":"2017","journal-title":"Fertil Steril"},{"key":"10.5534\/wjmh.240149_ref2","first-page":"336","volume":"50","author":"Poongothai","year":"2009","journal-title":"Singapore Med J"},{"key":"10.5534\/wjmh.240149_ref3","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.beem.2010.08.006","volume":"25","author":"Krausz","year":"2011","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.5534\/wjmh.240149_ref4","doi-asserted-by":"crossref","first-page":"e28218","DOI":"10.4161\/spmg.28218","volume":"4","author":"Wosnitzer","year":"2014","journal-title":"Spermatogenesis"},{"key":"10.5534\/wjmh.240149_ref5","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.reprotox.2006.04.016","volume":"22","author":"Ferlin","year":"2006","journal-title":"Reprod Toxicol"},{"key":"10.5534\/wjmh.240149_ref6","doi-asserted-by":"crossref","first-page":"3264","DOI":"10.3390\/ijms22063264","volume":"22","author":"Cioppi","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.5534\/wjmh.240149_ref7","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.21037\/tau-19-725","volume":"10","author":"Pelzman","year":"2021","journal-title":"Transl Androl Urol"},{"key":"10.5534\/wjmh.240149_ref8","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3390\/genes12030410","volume":"12","author":"Okutman","year":"2021","journal-title":"Genes (Basel)"},{"key":"10.5534\/wjmh.240149_ref9","first-page":"242","volume":"10","author":"Cannarella","year":"2020","journal-title":"Life (Basel)"},{"key":"10.5534\/wjmh.240149_ref10","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.ajhg.2022.01.011","volume":"109","author":"Kherraf","year":"2022","journal-title":"Am J Hum Genet"},{"key":"10.5534\/wjmh.240149_ref11","unstructured":"The Clinical Genome Resource Gene Curation Working Group. Gene clinical validity curation process: standard operating procedure [Internet]. The Clinical Genome Resource Gene Curation Working Group. c2019. cited 2022 Oct 24. Available from: https:\/\/clinicalgenome.org\/site\/assets\/files\/3975\/gene-disease_validity_standard_operating_procedures_version_7_highlighted_final.pdf"},{"key":"10.5534\/wjmh.240149_ref12","doi-asserted-by":"crossref","first-page":"e1000097","DOI":"10.1371\/journal.pmed.1000097","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med"},{"key":"10.5534\/wjmh.240149_ref13","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1111\/andr.12897","volume":"9","author":"Hod\u017ei\u0107","year":"2021","journal-title":"Andrology"},{"key":"10.5534\/wjmh.240149_ref14","unstructured":"ACGS Best Practice Guidelines for Variant Classification in Rare Disease 2020 [Internet]. Association for Clinical Genomic Science. c2020. cited 2022 Oct 24. Available from: https:\/\/www.acgs.uk.com\/media\/11631\/uk-practice-guidelines-for-variant-classification-v4-01-2020.pdf"},{"key":"10.5534\/wjmh.240149_ref15","doi-asserted-by":"crossref","first-page":"988202","DOI":"10.3389\/fgene.2022.988202","volume":"13","author":"Yuan","year":"2022","journal-title":"Front Genet"},{"key":"10.5534\/wjmh.240149_ref16","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.ajhg.2010.09.009","volume":"87","author":"Bashamboo","year":"2010","journal-title":"Am J Hum Genet"},{"key":"10.5534\/wjmh.240149_ref17","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/humupd\/dmab030","volume":"28","author":"Houston","year":"2021","journal-title":"Hum Reprod Update"},{"key":"10.5534\/wjmh.240149_ref18","doi-asserted-by":"crossref","first-page":"7953","DOI":"10.1038\/s41467-022-35661-z","volume":"13","author":"Nagirnaja","year":"2022","journal-title":"Nat Commun"},{"key":"10.5534\/wjmh.240149_ref19","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1111\/cge.13917","volume":"99","author":"Donohue","year":"2021","journal-title":"Clin Genet"},{"key":"10.5534\/wjmh.240149_ref20","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.ajhg.2017.04.015","volume":"100","author":"Strande","year":"2017","journal-title":"Am J Hum Genet"},{"key":"10.5534\/wjmh.240149_ref21","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/s41467-021-27132-8","volume":"13","author":"Oud","year":"2022","journal-title":"Nat Commun"},{"key":"10.5534\/wjmh.240149_ref22","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1093\/humupd\/dmac024","volume":"28","author":"Xie","year":"2022","journal-title":"Hum Reprod Update"},{"key":"10.5534\/wjmh.240149_ref23","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1096\/fj.99-0851com","volume":"14","author":"Santucci-Darmanin","year":"2000","journal-title":"FASEB J"},{"key":"10.5534\/wjmh.240149_ref24","doi-asserted-by":"crossref","first-page":"e1004413","DOI":"10.1371\/journal.pgen.1004413","volume":"10","author":"Hopkins","year":"2014","journal-title":"PLoS Genet"},{"key":"10.5534\/wjmh.240149_ref25","doi-asserted-by":"crossref","first-page":"4982","DOI":"10.1073\/pnas.0505123103","volume":"103","author":"Greenbaum","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.5534\/wjmh.240149_ref26","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1083\/jcb.200709057","volume":"180","author":"Yang","year":"2008","journal-title":"J Cell Biol"},{"key":"10.5534\/wjmh.240149_ref27","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.ajhg.2020.06.010","volume":"107","author":"Wyrwoll","year":"2020","journal-title":"Am J Hum Genet"},{"key":"10.5534\/wjmh.240149_ref28","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.bpobgyn.2017.05.002","volume":"44","author":"Flannigan","year":"2017","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"10.5534\/wjmh.240149_ref29","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1471-2490-6-9","volume":"6","author":"Everaert","year":"2006","journal-title":"BMC Urol"},{"key":"10.5534\/wjmh.240149_ref30","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1038\/nrurol.2015.238","volume":"12","author":"Aversa","year":"2015","journal-title":"Nat Rev Urol"}],"container-title":["The World Journal of Men's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/wjmh.org\/pdf\/10.5534\/wjmh.240149","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.240149","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.240149","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T02:50:24Z","timestamp":1758768624000},"score":1,"resource":{"primary":{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.240149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.5534\/wjmh.240149","relation":{},"ISSN":["2287-4208","2287-4690"],"issn-type":[{"value":"2287-4208","type":"print"},{"value":"2287-4690","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"2024-06-14","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-02","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-25","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-02","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2025 Korean Society for Sexual Medicine and Andrology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}