{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:47:24Z","timestamp":1787032044199,"version":"build-2736575974"},"reference-count":29,"publisher":"XMLink","issue":"3","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100013129","name":"Ministry of SMEs and Startups","doi-asserted-by":"publisher","award":["RS-2023-00285144"],"award-info":[{"award-number":["RS-2023-00285144"]}],"id":[{"id":"10.13039\/501100013129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82200759"],"award-info":[{"award-number":["82200759"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["wjmh.org"],"crossmark-restriction":false},"short-container-title":["World J Mens Health"],"published-print":{"date-parts":[[2026]]},"DOI":"10.5534\/wjmh.250152","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T05:43:13Z","timestamp":1760074993000},"page":"678","update-policy":"https:\/\/doi.org\/10.5534\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Intravesical Cannabidiol for Inflammation and Pain in Interstitial Cystitis\/Bladder Pain Syndrome\n                    <i>via<\/i>\n                    TLR4\/NF-\u03baB and TRPV1 Modulation"],"prefix":"10.5534","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8223-7487","authenticated-orcid":false,"given":"Jun Jie","family":"Piao","sequence":"first","affiliation":[{"name":"Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea."},{"name":"Catholic Integrative Medicine Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4834-9941","authenticated-orcid":false,"given":"Soomin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea."},{"name":"Catholic Integrative Medicine Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0907-6533","authenticated-orcid":false,"given":"Hwa Jong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea."},{"name":"Catholic Integrative Medicine Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7841-8026","authenticated-orcid":false,"given":"Guan Qun","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea."},{"name":"Catholic Integrative Medicine Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea."},{"name":"Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1201-6956","authenticated-orcid":false,"given":"Kyung-Hwa","family":"Jeon","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Ewha Womans University, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3611-8011","authenticated-orcid":false,"given":"Sang-Hyuck","family":"Park","sequence":"additional","affiliation":[{"name":"Institute of Cannabis Research, Colorado State University-Pueblo, Pueblo, CO, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0422-846X","authenticated-orcid":false,"given":"Rui-Li","family":"Guan","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University First Hospital, Beijing, China."},{"name":"Institute of Urology, Peking University, Beijing, China."},{"name":"Beijing Key Laboratory of Urogenital Diseases (Male) Molecular Diagnosis and Treatment Center, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6037-1319","authenticated-orcid":false,"given":"Wen Jie","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Urology, The Second Hospital of Jilin University, Changchun, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0361-2737","authenticated-orcid":false,"given":"Zhong Cheng","family":"Xin","sequence":"additional","affiliation":[{"name":"China-Korea Joint Research Center for Male Reproductive and Sexual Medicine, Tianjin Institute of Urology, Tianjin, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9127-9400","authenticated-orcid":false,"given":"Sae Woong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea."},{"name":"Catholic Integrative Medicine Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea."},{"name":"Green Medicine Co., Ltd., Busan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7703-1161","authenticated-orcid":false,"given":"Woong Jin","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea."},{"name":"Catholic Integrative Medicine Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.5534\/wjmh.250152_ref1","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.ucl.2022.01.003","volume":"49","author":"Chermansky","year":"2022","journal-title":"Urol Clin North Am"},{"key":"10.5534\/wjmh.250152_ref2","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.juro.2011.03.132","volume":"186","author":"Berry","year":"2011","journal-title":"J Urol"},{"key":"10.5534\/wjmh.250152_ref3","doi-asserted-by":"crossref","first-page":"14594","DOI":"10.3390\/ijms232314594","volume":"23","author":"Li","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.5534\/wjmh.250152_ref4","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.3390\/biomedicines10102380","volume":"10","author":"Jhang","year":"2022","journal-title":"Biomedicines"},{"key":"10.5534\/wjmh.250152_ref5","doi-asserted-by":"crossref","first-page":"12044","DOI":"10.3390\/ijms231912044","volume":"23","author":"Jiang","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.5534\/wjmh.250152_ref6","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1080\/15360288.2018.1476433","volume":"32","author":"Daniels","year":"2018","journal-title":"J Pain Palliat Care Pharmacother"},{"key":"10.5534\/wjmh.250152_ref7","doi-asserted-by":"crossref","first-page":"114517","DOI":"10.1016\/j.fct.2024.114517","volume":"186","author":"Xie","year":"2024","journal-title":"Food Chem Toxicol"},{"key":"10.5534\/wjmh.250152_ref8","doi-asserted-by":"crossref","first-page":"3067","DOI":"10.3390\/ijms21093067","volume":"21","author":"Mart\u00ednez","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.5534\/wjmh.250152_ref9","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.2147\/JPR.S258433","volume":"13","author":"Anand","year":"2020","journal-title":"J Pain Res"},{"key":"10.5534\/wjmh.250152_ref10","doi-asserted-by":"crossref","first-page":"5055","DOI":"10.3390\/ijms24055055","volume":"24","author":"Kuret","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.5534\/wjmh.250152_ref11","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.3389\/fphar.2020.01305","volume":"11","author":"Aug\u00e9","year":"2020","journal-title":"Front Pharmacol"},{"key":"10.5534\/wjmh.250152_ref12","doi-asserted-by":"crossref","first-page":"304","DOI":"10.21037\/tau-22-23","volume":"11","author":"Pang","year":"2022","journal-title":"Transl Androl Urol"},{"key":"10.5534\/wjmh.250152_ref13","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.juro.2008.08.121","volume":"181","author":"Charrua","year":"2009","journal-title":"J Urol"},{"key":"10.5534\/wjmh.250152_ref14","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s00210-006-0073-2","volume":"373","author":"Avelino","year":"2006","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.5534\/wjmh.250152_ref15","doi-asserted-by":"crossref","first-page":"26","DOI":"10.4103\/0970-1591.60440","volume":"26","author":"Tyagi","year":"2010","journal-title":"Indian J Urol"},{"key":"10.5534\/wjmh.250152_ref16","doi-asserted-by":"crossref","first-page":"133","DOI":"10.3389\/fphar.2019.00133","volume":"10","author":"Boudieu","year":"2019","journal-title":"Front Pharmacol"},{"key":"10.5534\/wjmh.250152_ref17","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1007\/s10068-023-01281-6","volume":"32","author":"Jeong","year":"2023","journal-title":"Food Sci Biotechnol"},{"key":"10.5534\/wjmh.250152_ref18","first-page":"50","volume":"10","author":"Andersson","year":"2022","journal-title":"Med Sci (Basel)"},{"key":"10.5534\/wjmh.250152_ref19","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/sj.bjp.0705920","volume":"143","author":"Costa","year":"2004","journal-title":"Br J Pharmacol"},{"key":"10.5534\/wjmh.250152_ref20","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1111\/bph.12502","volume":"171","author":"Franken","year":"2014","journal-title":"Br J Pharmacol"},{"key":"10.5534\/wjmh.250152_ref21","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0306-4522(01)00496-1","volume":"109","author":"Avelino","year":"2002","journal-title":"Neuroscience"},{"key":"10.5534\/wjmh.250152_ref22","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.ejphar.2004.07.037","volume":"500","author":"Nagy","year":"2004","journal-title":"Eur J Pharmacol"},{"key":"10.5534\/wjmh.250152_ref23","doi-asserted-by":"crossref","first-page":"50080","DOI":"10.1074\/jbc.M306619200","volume":"278","author":"Mohapatra","year":"2003","journal-title":"J Biol Chem"},{"key":"10.5534\/wjmh.250152_ref24","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1007\/s004240050074","volume":"431","author":"Docherty","year":"1996","journal-title":"Pflugers Arch"},{"key":"10.5534\/wjmh.250152_ref25","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1089\/can.2020.0181","volume":"6","author":"Johnson","year":"2021","journal-title":"Cannabis Cannabinoid Res"},{"key":"10.5534\/wjmh.250152_ref26","first-page":"5827","volume":"35","author":"Scott","year":"2015","journal-title":"Anticancer Res"},{"key":"10.5534\/wjmh.250152_ref27","doi-asserted-by":"crossref","first-page":"102489","DOI":"10.1016\/j.redox.2022.102489","volume":"57","author":"Atalay Ekiner","year":"2022","journal-title":"Redox Biol"},{"key":"10.5534\/wjmh.250152_ref28","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1007\/s00210-024-03391-2","volume":"398","author":"\u0130lhan","year":"2025","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.5534\/wjmh.250152_ref29","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1111\/jre.13178","volume":"58","author":"Montreekachon","year":"2023","journal-title":"J Periodontal Res"}],"container-title":["The World Journal of Men's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/wjmh.org\/pdf\/10.5534\/wjmh.250152","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.250152","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.250152","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:41:26Z","timestamp":1781484086000},"score":1,"resource":{"primary":{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.250152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.5534\/wjmh.250152","relation":{},"ISSN":["2287-4208","2287-4690"],"issn-type":[{"value":"2287-4208","type":"print"},{"value":"2287-4690","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"2025-05-03","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-23","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-01","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2026 Korean Society for Sexual Medicine and Andrology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}