{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:30:01Z","timestamp":1789659001680,"version":"4.0.1"},"reference-count":98,"publisher":"XMLink","issue":"4","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"Sichuan Science and Technology Program","award":["2024NSFSC0684-Xunjun Yu"],"award-info":[{"award-number":["2024NSFSC0684-Xunjun Yu"]}]},{"name":"National Natural Science Foundation of China General Project","award":["Dong Liang-82205131"],"award-info":[{"award-number":["Dong Liang-82205131"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100008402","name":"Chengdu University of Traditional Chinese Medicine","doi-asserted-by":"publisher","award":["Zhou Lu-202410633065"],"award-info":[{"award-number":["Zhou Lu-202410633065"]}],"id":[{"id":"10.13039\/501100008402","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["wjmh.org"],"crossmark-restriction":false},"short-container-title":["World J Mens Health"],"published-print":{"date-parts":[[2026]]},"DOI":"10.5534\/wjmh.250248","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:52:21Z","timestamp":1770943941000},"page":"788","update-policy":"https:\/\/doi.org\/10.5534\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Restoring NAD\n                    <sup>+<\/sup>\n                    -Sirtuins Signaling: A Novel Approach to Combat Male Reproductive Aging"],"prefix":"10.5534","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8695-6606","authenticated-orcid":false,"given":"Lu","family":"Zhou","sequence":"first","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9830-3525","authenticated-orcid":false,"given":"Xiucheng","family":"Lan","sequence":"additional","affiliation":[{"name":"TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8292-8616","authenticated-orcid":false,"given":"Meijing","family":"Wang","sequence":"additional","affiliation":[{"name":"TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3543-6589","authenticated-orcid":false,"given":"Xiaoya","family":"Li","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6060-3279","authenticated-orcid":false,"given":"Xin","family":"Zeng","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5919-5787","authenticated-orcid":false,"given":"Sixue","family":"Peng","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7977-0336","authenticated-orcid":false,"given":"Jingyi","family":"Zhang","sequence":"additional","affiliation":[{"name":"TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2956-9079","authenticated-orcid":false,"given":"Junjun","family":"Li","sequence":"additional","affiliation":[{"name":"Chengdu Fifth People\u2019s Hospital, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6628-2106","authenticated-orcid":false,"given":"Liang","family":"Dong","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5620-6783","authenticated-orcid":false,"given":"Xujun","family":"Yu","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine, Chengdu, China."},{"name":"TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3964-1791","authenticated-orcid":false,"given":"Fang","family":"Yang","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.5534\/wjmh.250248_ref1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.maturitas.2014.02.011","volume":"78","author":"Belloc","year":"2014","journal-title":"Maturitas"},{"key":"10.5534\/wjmh.250248_ref2","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.fertnstert.2016.12.021","volume":"107","author":"Herati","year":"2017","journal-title":"Fertil Steril"},{"key":"10.5534\/wjmh.250248_ref3","doi-asserted-by":"crossref","first-page":"e1019","DOI":"10.1038\/tp.2016.294","volume":"7","author":"Janecka","year":"2017","journal-title":"Transl Psychiatry"},{"key":"10.5534\/wjmh.250248_ref4","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1001\/jamapsychiatry.2013.4525","volume":"71","author":"D'Onofrio","year":"2014","journal-title":"JAMA Psychiatry"},{"key":"10.5534\/wjmh.250248_ref5","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.tcb.2014.04.002","volume":"24","author":"Imai","year":"2014","journal-title":"Trends Cell Biol"},{"key":"10.5534\/wjmh.250248_ref6","doi-asserted-by":"crossref","first-page":"132","DOI":"10.12688\/f1000research.12120.1","volume":"7","author":"Johnson","year":"2018","journal-title":"F1000Re"},{"key":"10.5534\/wjmh.250248_ref7","doi-asserted-by":"crossref","first-page":"896356","DOI":"10.3389\/fendo.2022.896356","volume":"13","author":"Meyer-Ficca","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.5534\/wjmh.250248_ref8","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3390\/genes16010093","volume":"16","author":"Kaltsas","year":"2025","journal-title":"Genes (Basel)"},{"key":"10.5534\/wjmh.250248_ref9","doi-asserted-by":"crossref","first-page":"2622","DOI":"10.7150\/thno.92416","volume":"14","author":"Feng","year":"2024","journal-title":"Theranostics"},{"key":"10.5534\/wjmh.250248_ref10","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/s41580-020-00313-x","volume":"22","author":"Covarrubias","year":"2021","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.5534\/wjmh.250248_ref11","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1089\/ars.2007.1672","volume":"10","author":"Ying","year":"2008","journal-title":"Antioxid Redox Signal"},{"key":"10.5534\/wjmh.250248_ref12","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.anireprosci.2007.11.029","volume":"105","author":"Johnson","year":"2008","journal-title":"Anim Reprod Sci"},{"key":"10.5534\/wjmh.250248_ref13","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.tem.2004.07.003","volume":"15","author":"Boussouar","year":"2004","journal-title":"Trends Endocrinol Metab"},{"key":"10.5534\/wjmh.250248_ref14","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/iub.1017","volume":"64","author":"Stanton","year":"2012","journal-title":"IUBMB Life"},{"key":"10.5534\/wjmh.250248_ref15","doi-asserted-by":"crossref","first-page":"e70004","DOI":"10.1111\/acel.70004","volume":"24","author":"Xu","year":"2025","journal-title":"Aging Cell"},{"key":"10.5534\/wjmh.250248_ref16","first-page":"5915705","volume":"5","author":"Ren","year":"2025","journal-title":"Environ Sci Technol"},{"key":"10.5534\/wjmh.250248_ref17","doi-asserted-by":"crossref","first-page":"104775","DOI":"10.1016\/j.etap.2025.104775","volume":"118","author":"Centola","year":"2025","journal-title":"Environ Toxicol Pharmacol"},{"key":"10.5534\/wjmh.250248_ref18","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.cbpa.2012.10.003","volume":"16","author":"Sauve","year":"2012","journal-title":"Curr Opin Chem Biol"},{"key":"10.5534\/wjmh.250248_ref19","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jgg.2021.11.005","volume":"49","author":"Ji","year":"2022","journal-title":"J Genet Genomics"},{"key":"10.5534\/wjmh.250248_ref20","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.tem.2013.12.001","volume":"25","author":"Chang","year":"2014","journal-title":"Trends Endocrinol Metab"},{"key":"10.5534\/wjmh.250248_ref21","doi-asserted-by":"crossref","first-page":"2905","DOI":"10.1080\/15384101.2015.1069928","volume":"14","author":"Xiong","year":"2015","journal-title":"Cell Cycle"},{"key":"10.5534\/wjmh.250248_ref22","doi-asserted-by":"crossref","first-page":"3456","DOI":"10.1172\/JCI57984","volume":"121","author":"Goertz","year":"2011","journal-title":"J Clin Invest"},{"key":"10.5534\/wjmh.250248_ref23","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.2174\/0929867323666160229114248","volume":"23","author":"Rato","year":"2016","journal-title":"Curr Med Chem"},{"key":"10.5534\/wjmh.250248_ref24","doi-asserted-by":"crossref","first-page":"e12690","DOI":"10.1111\/jpi.12690","volume":"69","author":"Xu","year":"2020","journal-title":"J Pineal Res"},{"key":"10.5534\/wjmh.250248_ref25","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1242\/dev.147074","volume":"144","author":"Liu","year":"2017","journal-title":"Development"},{"key":"10.5534\/wjmh.250248_ref26","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.3390\/ijms22042021","volume":"22","author":"Galano","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.5534\/wjmh.250248_ref27","doi-asserted-by":"crossref","first-page":"3084","DOI":"10.3390\/molecules24173084","volume":"24","author":"Xu","year":"2019","journal-title":"Molecules"},{"key":"10.5534\/wjmh.250248_ref28","doi-asserted-by":"crossref","first-page":"8177","DOI":"10.1038\/s41598-021-87759-x","volume":"11","author":"Majeed","year":"2021","journal-title":"Sci Rep"},{"key":"10.5534\/wjmh.250248_ref29","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1186\/s12906-022-03615-z","volume":"22","author":"Li","year":"2022","journal-title":"BMC Complement Med Ther"},{"key":"10.5534\/wjmh.250248_ref30","doi-asserted-by":"crossref","first-page":"3495","DOI":"10.1242\/dev.110627","volume":"141","author":"Bell","year":"2014","journal-title":"Development"},{"key":"10.5534\/wjmh.250248_ref31","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1007\/s11010-021-04116-2","volume":"476","author":"Loganathan","year":"2021","journal-title":"Mol Cell Biochem"},{"key":"10.5534\/wjmh.250248_ref32","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/bs.acr.2021.01.006","volume":"150","author":"Sharma","year":"2021","journal-title":"Adv Cancer Res"},{"key":"10.5534\/wjmh.250248_ref33","first-page":"1708251","volume":"2023","author":"Xiao","year":"2023","journal-title":"Oxid Med Cell Longev"},{"key":"10.5534\/wjmh.250248_ref34","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13008-024-00124-y","volume":"19","author":"Xi","year":"2024","journal-title":"Cell Div"},{"key":"10.5534\/wjmh.250248_ref35","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.bbrc.2021.03.138","volume":"555","author":"Wang","year":"2021","journal-title":"Biochem Biophys Res Commun"},{"key":"10.5534\/wjmh.250248_ref36","first-page":"1314","volume":"59","author":"Yang","year":"2021","journal-title":"Pharm Biol"},{"key":"10.5534\/wjmh.250248_ref37","doi-asserted-by":"crossref","first-page":"e11707","DOI":"10.1371\/journal.pone.0011707","volume":"5","author":"Kong","year":"2010","journal-title":"PLoS One"},{"key":"10.5534\/wjmh.250248_ref38","doi-asserted-by":"crossref","first-page":"bqae017","DOI":"10.1210\/endocr\/bqae017","volume":"165","author":"Matoba","year":"2024","journal-title":"Endocrinology"},{"key":"10.5534\/wjmh.250248_ref39","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/j.tcb.2021.06.009","volume":"31","author":"Korotkov","year":"2021","journal-title":"Trends Cell Biol"},{"key":"10.5534\/wjmh.250248_ref40","doi-asserted-by":"crossref","first-page":"17099","DOI":"10.18632\/aging.103641","volume":"12","author":"Wei","year":"2020","journal-title":"Aging (Albany NY)"},{"key":"10.5534\/wjmh.250248_ref41","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S1097-2765(03)00038-8","volume":"11","author":"North","year":"2003","journal-title":"Mol Cell"},{"key":"10.5534\/wjmh.250248_ref42","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.3390\/antiox10071047","volume":"10","author":"Di Emidio","year":"2021","journal-title":"Antioxidants (Basel)"},{"key":"10.5534\/wjmh.250248_ref43","doi-asserted-by":"crossref","first-page":"811","DOI":"10.15252\/embr.201541643","volume":"17","author":"Zhou","year":"2016","journal-title":"EMBO Rep"},{"key":"10.5534\/wjmh.250248_ref44","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.3390\/cells10113114","volume":"10","author":"Matzkin","year":"2021","journal-title":"Cells"},{"key":"10.5534\/wjmh.250248_ref45","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/s12894-022-01107-3","volume":"22","author":"Bai","year":"2022","journal-title":"BMC Urol"},{"key":"10.5534\/wjmh.250248_ref46","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/s43587-024-00614-2","volume":"4","author":"Deng","year":"2024","journal-title":"Nat Aging"},{"key":"10.5534\/wjmh.250248_ref47","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1002\/cbf.3860","volume":"41","author":"Sun","year":"2023","journal-title":"Cell Biochem Funct"},{"key":"10.5534\/wjmh.250248_ref48","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0070-2153(05)71008-5","volume":"71","author":"Wong","year":"2005","journal-title":"Curr Top Dev Biol"},{"key":"10.5534\/wjmh.250248_ref49","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1002\/tox.23706","volume":"38","author":"Shen","year":"2023","journal-title":"Environ Toxicol"},{"key":"10.5534\/wjmh.250248_ref50","doi-asserted-by":"crossref","first-page":"1274035","DOI":"10.3389\/fendo.2023.1274035","volume":"14","author":"Falvo","year":"2023","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.5534\/wjmh.250248_ref51","doi-asserted-by":"crossref","first-page":"102886","DOI":"10.1016\/j.redox.2023.102886","volume":"67","author":"Zeng","year":"2023","journal-title":"Redox Biol"},{"key":"10.5534\/wjmh.250248_ref52","doi-asserted-by":"crossref","first-page":"1012119","DOI":"10.3389\/fendo.2022.1012119","volume":"13","author":"Dong","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.5534\/wjmh.250248_ref53","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.nbd.2018.09.006","volume":"126","author":"Stamatovic","year":"2019","journal-title":"Neurobiol Dis"},{"key":"10.5534\/wjmh.250248_ref54","doi-asserted-by":"crossref","first-page":"303","DOI":"10.4161\/spmg.1.4.18392","volume":"1","author":"Pointis","year":"2011","journal-title":"Spermatogenesis"},{"key":"10.5534\/wjmh.250248_ref55","doi-asserted-by":"crossref","first-page":"12898","DOI":"10.1038\/s41598-022-16919-4","volume":"12","author":"Staggenborg","year":"2022","journal-title":"Sci Rep"},{"key":"10.5534\/wjmh.250248_ref56","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/s43587-025-00824-2","volume":"5","author":"Cui","year":"2025","journal-title":"Nat Aging"},{"key":"10.5534\/wjmh.250248_ref57","doi-asserted-by":"crossref","first-page":"114603","DOI":"10.1016\/j.yexcr.2025.114603","volume":"449","author":"Zhou","year":"2025","journal-title":"Exp Cell Res"},{"key":"10.5534\/wjmh.250248_ref58","doi-asserted-by":"crossref","first-page":"e0155173","DOI":"10.1371\/journal.pone.0155173","volume":"11","author":"Chen","year":"2016","journal-title":"PLoS One"},{"key":"10.5534\/wjmh.250248_ref59","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/nature08778","volume":"464","author":"Hirschey","year":"2010","journal-title":"Nature"},{"key":"10.5534\/wjmh.250248_ref60","doi-asserted-by":"crossref","first-page":"113144","DOI":"10.1016\/j.expneurol.2019.113144","volume":"325","author":"Klimova","year":"2020","journal-title":"Exp Neurol"},{"key":"10.5534\/wjmh.250248_ref61","doi-asserted-by":"crossref","first-page":"116461","DOI":"10.1016\/j.ecoenv.2024.116461","volume":"279","author":"Liang","year":"2024","journal-title":"Ecotoxicol Environ Saf"},{"key":"10.5534\/wjmh.250248_ref62","doi-asserted-by":"crossref","first-page":"102227","DOI":"10.1016\/j.redox.2021.102227","volume":"49","author":"Guo","year":"2022","journal-title":"Redox Biol"},{"key":"10.5534\/wjmh.250248_ref63","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1002\/tox.23096","volume":"36","author":"Dong","year":"2021","journal-title":"Environ Toxicol"},{"key":"10.5534\/wjmh.250248_ref64","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1186\/s12964-023-01177-2","volume":"21","author":"Chen","year":"2023","journal-title":"Cell Commun Signal"},{"key":"10.5534\/wjmh.250248_ref65","doi-asserted-by":"crossref","first-page":"113810","DOI":"10.1016\/j.jep.2021.113810","volume":"271","author":"Li","year":"2021","journal-title":"J Ethnopharmacol"},{"key":"10.5534\/wjmh.250248_ref66","doi-asserted-by":"crossref","first-page":"3328","DOI":"10.3390\/ijms20133328","volume":"20","author":"Kelley","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.5534\/wjmh.250248_ref67","doi-asserted-by":"crossref","first-page":"114280","DOI":"10.1016\/j.intimp.2025.114280","volume":"151","author":"Wei","year":"2025","journal-title":"Int Immunopharmacol"},{"key":"10.5534\/wjmh.250248_ref68","doi-asserted-by":"crossref","first-page":"102584","DOI":"10.1016\/j.redox.2022.102584","volume":"59","author":"Zhao","year":"2023","journal-title":"Redox Biol"},{"key":"10.5534\/wjmh.250248_ref69","doi-asserted-by":"crossref","first-page":"117482","DOI":"10.1016\/j.biopha.2024.117482","volume":"180","author":"Liu","year":"2024","journal-title":"Biomed Pharmacother"},{"key":"10.5534\/wjmh.250248_ref70","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.jare.2022.12.007","volume":"53","author":"Zhang","year":"2023","journal-title":"J Adv Res"},{"key":"10.5534\/wjmh.250248_ref71","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0165-0378(02)00020-7","volume":"57","author":"Hales","year":"2002","journal-title":"J Reprod Immunol"},{"key":"10.5534\/wjmh.250248_ref72","doi-asserted-by":"crossref","first-page":"1186231","DOI":"10.3389\/fimmu.2023.1186231","volume":"14","author":"Tao","year":"2023","journal-title":"Front Immunol"},{"key":"10.5534\/wjmh.250248_ref73","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/s41422-025-01080-0","volume":"35","author":"Lin","year":"2025","journal-title":"Cell Res"},{"key":"10.5534\/wjmh.250248_ref74","doi-asserted-by":"crossref","first-page":"21598","DOI":"10.1038\/s41598-024-72595-6","volume":"14","author":"Nevoral","year":"2024","journal-title":"Sci Rep"},{"key":"10.5534\/wjmh.250248_ref75","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1038\/emboj.2009.314","volume":"29","author":"Kozak","year":"2010","journal-title":"EMBO J"},{"key":"10.5534\/wjmh.250248_ref76","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s40104-019-0372-3","volume":"10","author":"Nevoral","year":"2019","journal-title":"J Anim Sci Biotechnol"},{"key":"10.5534\/wjmh.250248_ref77","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/npp.2012.112","volume":"38","author":"Moore","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"10.5534\/wjmh.250248_ref78","doi-asserted-by":"crossref","first-page":"4720","DOI":"10.1128\/MCB.06147-11","volume":"31","author":"Peng","year":"2011","journal-title":"Mol Cell Biol"},{"key":"10.5534\/wjmh.250248_ref79","doi-asserted-by":"crossref","first-page":"4496","DOI":"10.2174\/1381612826666200716161610","volume":"26","author":"Torres","year":"2020","journal-title":"Curr Pharm Des"},{"key":"10.5534\/wjmh.250248_ref80","doi-asserted-by":"crossref","first-page":"5087","DOI":"10.3390\/ijms25105087","volume":"25","author":"Anastasio","year":"2024","journal-title":"Int J Mol Sci"},{"key":"10.5534\/wjmh.250248_ref81","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.molcel.2013.10.010","volume":"52","author":"Chen","year":"2013","journal-title":"Mol Cell"},{"key":"10.5534\/wjmh.250248_ref82","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1095\/biolreprod.108.070193","volume":"80","author":"Kolthur-Seetharam","year":"2009","journal-title":"Biol Reprod"},{"key":"10.5534\/wjmh.250248_ref83","doi-asserted-by":"crossref","first-page":"144","DOI":"10.3945\/an.113.005181","volume":"5","author":"Pinto","year":"2014","journal-title":"Adv Nutr"},{"key":"10.5534\/wjmh.250248_ref84","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.steroids.2015.08.001","volume":"103","author":"Tremblay","year":"2015","journal-title":"Steroids"},{"key":"10.5534\/wjmh.250248_ref85","first-page":"1314","volume":"54","author":"Ma","year":"2022","journal-title":"Acta Biochim Biophys Sin (Shanghai)"},{"key":"10.5534\/wjmh.250248_ref86","doi-asserted-by":"crossref","first-page":"507","DOI":"10.3390\/antiox13050507","volume":"13","author":"Zhang","year":"2024","journal-title":"Antioxidants (Basel)"},{"key":"10.5534\/wjmh.250248_ref87","doi-asserted-by":"crossref","first-page":"3634","DOI":"10.1016\/j.neuron.2023.08.010","volume":"111","author":"Zhan","year":"2023","journal-title":"Neuron"},{"key":"10.5534\/wjmh.250248_ref88","doi-asserted-by":"crossref","first-page":"5101","DOI":"10.3390\/nu14235101","volume":"14","author":"Grzeczka","year":"2022","journal-title":"Nutrients"},{"key":"10.5534\/wjmh.250248_ref89","doi-asserted-by":"crossref","first-page":"e14417","DOI":"10.1111\/and.14417","volume":"54","author":"Mendes","year":"2022","journal-title":"Andrologia"},{"key":"10.5534\/wjmh.250248_ref90","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3390\/molecules26010229","volume":"26","author":"Meng","year":"2021","journal-title":"Molecules"},{"key":"10.5534\/wjmh.250248_ref91","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.tiv.2017.06.027","volume":"44","author":"Cormier","year":"2017","journal-title":"Toxicol In Vitro"},{"key":"10.5534\/wjmh.250248_ref92","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/s41467-023-36543-8","volume":"14","author":"Yang","year":"2023","journal-title":"Nat Commun"},{"key":"10.5534\/wjmh.250248_ref93","doi-asserted-by":"crossref","first-page":"3709","DOI":"10.3390\/ijms22073709","volume":"22","author":"Khaidizar","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.5534\/wjmh.250248_ref94","first-page":"2828","volume":"15","author":"Di Emidio","year":"2024","journal-title":"Aging Dis"},{"key":"10.5534\/wjmh.250248_ref95","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.cmet.2016.05.006","volume":"23","author":"Camacho-Pereira","year":"2016","journal-title":"Cell Metab"},{"key":"10.5534\/wjmh.250248_ref96","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.freeradbiomed.2022.12.084","volume":"195","author":"Li","year":"2023","journal-title":"Free Radic Biol Med"},{"key":"10.5534\/wjmh.250248_ref97","doi-asserted-by":"crossref","first-page":"101935","DOI":"10.1016\/j.arr.2023.101935","volume":"87","author":"Neto","year":"2023","journal-title":"Ageing Res Rev"},{"key":"10.5534\/wjmh.250248_ref98","doi-asserted-by":"crossref","first-page":"2717","DOI":"10.3390\/ijms20112717","volume":"20","author":"Vargas-Ortiz","year":"2019","journal-title":"Int J Mol Sci"}],"container-title":["The World Journal of Men's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/wjmh.org\/pdf\/10.5534\/wjmh.250248","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.250248","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.250248","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:55:16Z","timestamp":1789624516000},"score":1,"resource":{"primary":{"URL":"https:\/\/wjmh.org\/DOIx.php?id=10.5534\/wjmh.250248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":98,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.5534\/wjmh.250248","relation":{},"ISSN":["2287-4208","2287-4690"],"issn-type":[{"value":"2287-4208","type":"print"},{"value":"2287-4690","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"2025-08-06","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-29","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-09","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-06","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2026 Korean Society for Sexual Medicine and Andrology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}