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J Intern Med, 1991; 229: 225-231","DOI":"10.1111\/j.1365-2796.1991.tb00336.x"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Burke GL, Evans GW, Riley WA, Sharrett AR, Howard G, Barnes RW Rosamond W, Crow RS, Rautaharju PM, Heiss G: Arterial wall thickness is associated with prevalent cardiovascular disease in middle-aged adults. The Atherosclerosis Risk in Communities (ARIC) Study. Stroke, 1995; 26: 386-391","DOI":"10.1161\/01.STR.26.3.386"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Grobbee DE, Bots ML: Carotid artery intima-media thickness as an indicator of generalized atherosclerosis. J Intern Med, 1994; 236: 567-573","DOI":"10.1111\/j.1365-2796.1994.tb00847.x"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Howard G, Sharrett AR, Heiss G, Evans GW, Chambless LE, Riley WA, Burke GL: Carotid artery intimalmedial thickness distribution in general populations as evaluated by B-mode ultrasound. ARIC Investigators. Stroke, 1993; 24: 1297-1304","DOI":"10.1161\/01.STR.24.9.1297"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Cao JJ, Arnold AM, Manolio TA, Polak JF, Psaty BM, Hirsch CH, Kuller LH, Cushman M: Association of carotid artery intimamedia thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: The Cardiovascular Health Study. Circulation, 2007; 116: 32-38","DOI":"10.1161\/CIRCULATIONAHA.106.645606"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Chambless LE, Folsom AR, Clegg LX, Sharrett AR, Shahar E, Nieto FJ, Rosamond WD, Evans G: Carotid wall thickness is predictive of incident clinical stroke: The Atherosclerosis Risk in Communities (ARIC) study. Am J Epidemiol, 2000; 151: 478-487","DOI":"10.1093\/oxfordjournals.aje.a010233"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Iglesias del Sol A, Bots ML, Grobbee DE, Hofman A, Witteman JC: Carotid intima-media thickness at different sites: Relation to incident myocardial infarction; The Rotterdam Study. Eur Heart J, 2002; 23: 934-940","DOI":"10.1053\/euhj.2001.2965"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Rosvall M, Janzon L, Berglund G, Engstr\u00f6m G, Hedblad B: Incidence of stroke is related to carotid IMT even in the absence of plaque. Atherosclerosis, 2005; 179: 325-331","DOI":"10.1016\/j.atherosclerosis.2004.10.015"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Lorenz MW, von Kegler S, Steinmetz H, Markus HS, Sitzer M: Carotid intima-media thickening indicates a higher vascular risk across a wide age range: Prospective data from the Carotid Atherosclerosis Progression Study (CAPS). Stroke, 2006; 37: 87-92","DOI":"10.1161\/01.STR.0000196964.24024.ea"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M: Prediction of clinical cardiovascular events with carotid intima-media thickness: A systematic review and metaanalysis. Circulation, 2007; 115: 459-467","DOI":"10.1161\/CIRCULATIONAHA.106.628875"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Greenland P, Alpert JS, Beller GA, Benjamin EJ, Budoff MJ, Fayad ZA, Foster E, Hlatky MA, Hodgson JM, Kushner FG, Lauer MS, Shaw LJ, Smith SC Jr, Taylor AJ, Weintraub WS, Wenger NK, Jacobs AK, Smith SC Jr, Anderson JL, Albert N, Buller CE, Creager MA, Ettinger SM, Guyton RA, Halperin JL, Hochman JS, Kushner FG, Nishimura R, Ohman EM, Page RL, Stevenson WG, Tarkington LG, Yancy CW; American College of Cardiology Foundation; American Heart Association: 2010 ACCF\/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: A report of the American College of Cardiology Foundation\/ American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol, 2010; 56: e50-e103","DOI":"10.1016\/j.jacc.2010.09.001"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Furberg CD1, Adams HP Jr, Applegate WB, Byington RP, Espeland MA, Hartwell T, Hunninghake DB, Lefkowitz DS, Probstfield J, Riley WA,Young B: Effect of lovastatin on early carotid atherosclerosis and cardiovascular events. Asymptomatic Carotid Artery Progression Study (ACAPS) Research Group. Circulation, 1994; 90: 1679-1687","DOI":"10.1161\/01.CIR.90.4.1679"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Taylor AJ, Kent SM, Flaherty PJ, Coyle LC, Markwood TT, Vernalis MN: ARBITER: Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol: A randomized trial comparing the effects of atorvastatin and pravastatin on carotid intima medial thickness. Circulation, 2002; 106: 2055-2060","DOI":"10.1161\/01.CIR.0000034508.55617.65"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Smilde TJ, van Wissen S, Wollersheim H, Trip MD, Kastelein JJ, Stalenhoef AF: Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolaemia (ASAP): A prospective, randomised, double-blind trial. Lancet, 2001; 357: 577-581","DOI":"10.1016\/S0140-6736(00)04053-8"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Hedblad B, Wikstrand J, Janzon L, Wedel H, Berglund G: Low-dose metoprolol CR\/XL and fluvastatin slow progression of carotid intima-media thickness: Main results from the Beta-Blocker Cholesterol-Lowering Asymptomatic Plaque Study (BCAPS). Circulation, 2001; 103: 1721-1726","DOI":"10.1161\/01.CIR.103.13.1721"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Lonn EM1, Gerstein HC, Sheridan P, Smith S, Diaz R, Mohan V, Bosch J, Yusuf S, Dagenais GR; DREAM (Diabetes REduction Assessment with ramipril and rosiglitazone Medication) and STARR Investigators: Effect of ramipril and of rosiglitazone on carotid intima-media thickness in people with impaired glucose tolerance or impaired fasting glucose: STARR (STudy of Atherosclerosis with Ramipril and Rosiglitazone). J Am Coll Cardiol, 2009; 53: 2028-2035","DOI":"10.1016\/j.jacc.2008.12.072"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Hodis HN, Mack WJ, LaBree L, Selzer RH, Liu C, Alaupovic P, Kwong-Fu H, Azen SP: Reduction in carotid arterial wall thickness using lovastatin and dietary therapy: A randomized controlled clinical trial. Ann Intern Med, 1996; 124: 548-556","DOI":"10.7326\/0003-4819-124-6-199603150-00002"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Crouse JR 3rd, Raichlen JS, Riley WA, Evans GW, Palmer MK, O'Leary DH, Grobbee DE, Bots ML; METEOR Study Group: Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: The METEOR Trial. JAMA, 2007; 297: 1344-1353","DOI":"10.1001\/jama.297.12.1344"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Hodis HN, Mack WJ, Zheng L, Li Y, Torres M, Sevilla D, Stewart Y, Hollen B, Garcia K, Alaupovic P, Buchanan TA: Effect of peroxisome proliferator-activated receptor gamma agonist treatment on subclinical atherosclerosis in patients with insulin-requiring type 2 diabetes. Diabetes Care, 2006; 29: 1545-1553","DOI":"10.2337\/dc05-2462"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Hosomi N, Mizushige K, Ohyama H, Takahashi T, Kitadai M, Hatanaka Y, Matsuo H, Kohno M, Koziol JA: Angiotensin-converting enzyme inhibition with enalapril slows progressive intima-media thickening of the common carotid artery in patients with non-insulin-dependent diabetes mellitus. Stroke, 2001; 32: 1539-1545","DOI":"10.1161\/01.STR.32.7.1539"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Costanzo P, Perrone-Filardi P, Vassallo E, Paolillo S, Cesarano P, Brevetti G, Chiariello M: Does carotid intima-media thickness regression predict reduction of cardiovascular events? A meta-analysis of 41 randomized trials. J Am Coll Cardiol, 2010; 56: 2006-2020","DOI":"10.1016\/j.jacc.2010.05.059"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Lorenz MW, Polak JF, Kavousi M, Mathiesen EB, V\u00f6lzke H, Tuomainen TP, Sander D, Plichart M, Catapano AL, Robertson CM, Kiechl S, Rundek T, Desvarieux M, Lind L, Schmid C, DasMahapatra P, Gao L, Ziegelbauer K, Bots ML, Thompson SG; PROG-IMT Study Group: Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): A meta-analysis of individual participant data. Lancet, 2012; 379: 2053-2062","DOI":"10.1016\/S0140-6736(12)60441-3"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) van den Oord SC, Sijbrands EJ, ten Kate GL, van Klaveren D, van Domburg RT, van der Steen AF, Schinkel AF: Carotid intima-media thickness for cardiovascular risk assessment: Systematic review and meta-analysis. Atherosclerosis, 2013; 228: 1-11","DOI":"10.1016\/j.atherosclerosis.2013.01.025"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Den Ruijter HM, Peters SA, Anderson TJ, Britton AR, Dekker JM, Eijkemans MJ, Engstr\u00f6m G, Evans GW, de Graaf J, Grobbee DE, Hedblad B, Hofman A, Holewijn S, Ikeda A, Kavousi M, Kitagawa K, Kitamura A, Koffijberg H, Lonn EM, Lorenz MW, Mathiesen EB, Nijpels G, Okazaki S, O'Leary DH, Polak JF, Price JF, Robertson C, Rembold CM, Rosvall M, Rundek T, Salonen JT, Sitzer M, Stehouwer CD, Witteman JC, Moons KG, Bots ML: Common carotid intima-media thickness measurements in cardiovascular risk prediction: A metaanalysis. JAMA, 2012; 308: 796-803","DOI":"10.1001\/jama.2012.9630"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Goff DC, Lloyd-Jones DM, Bennett G, Coady S, D'Agostino RB, Gibbons R, Greenland P, Lackland DT, Levy D, O'Donnell CJ, Robinson JG, Schwartz JS, Shero ST, Smith SC Jr, Sorlie P, Stone NJ, Wilson PW; American College of Cardiology\/American Heart Association Task Force on Practice Guidelines: 2013 ACC\/AHA guideline on the assessment of cardiovascular risk: A report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol, 2014; 63: 2935-2959","DOI":"10.1016\/j.jacc.2013.11.005"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) St\u00f6rk S, van den Beld AW, von Schacky C, Angermann CE, Lamberts SW, Grobbee DE, Bots ML: Carotid artery plaque burden, stiffness, and mortality risk in elderly men: A prospective, population-based cohort study. Circulation, 2004; 110: 344-348","DOI":"10.1161\/01.CIR.0000134966.10793.C9"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Belcaro G, Nicolaides AN, Ramaswami G, Cesarone MR, De Sanctis M, Incandela L, Ferrari P, Geroulakos G, Barsotti A, Griffin M, Dhanjil S, Sabetai M, Bucci M, Martines G: Carotid and femoral ultrasound morphology screening and cardiovascular events in low risk subjects: A 10-year follow-up study (the CAFES-CAVE study(1)). Atherosclerosis, 2001; 156: 379-387","DOI":"10.1016\/S0021-9150(00)00665-1"},{"key":"28","unstructured":"28) Onut R, Balanescu AP, Constantinescu D, Calmac L, Marinescu M, Dorobantu PM: Imaging Atherosclerosis by Carotid Intima-media Thickness in vivo: How to, Where and in Whom ? Maedica (Buchar), 2012; 7: 153-162"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Stein JH, Korcarz CE, Hurst RT, Lonn E, Kendall CB, Mohler ER, Najjar SS, Rembold CM, Post WS; American Society of Echocardiography Carotid Intima-Media Thickness Task Force: Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: A consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Endorsed by the Society for Vascular Medicine. J Am Soc Echocardiogr, 2008; 21: 93-111; quiz 189-190","DOI":"10.1016\/j.echo.2007.11.011"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Touboul PJ, Hennerici MG, Meairs S, Adams H, Amarenco P, Bornstein N, Csiba L, Desvarieux M, Ebrahim S, Hernandez Hernandez R, Jaff M, Kownator S, Naqvi T, Prati P, Rundek T, Sitzer M, Schminke U, Tardif JC, Taylor A, Vicaut E, Woo KS: Mannheim carotid intimamedia thickness and plaque consensus (2004-2006-2011). An update on behalf of the advisory board of the 3rd, 4th and 5th watching the risk symposia, at the 13th, 15th and 20th European Stroke Conferences, Mannheim, Germany, 2004, Brussels, Belgium, 2006, and Hamburg, Germany, 2011. Cerebrovasc Dis, 2012; 34: 290-296","DOI":"10.1159\/000343145"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Touboul PJ, Hennerici MG, Meairs S, Adams H, Amarenco P, Bornstein N, Csiba L, Desvarieux M, Ebrahim S, Fatar M, Hernandez Hernandez R, Jaff M, Kownator S, Prati P, Rundek T, Sitzer M, Schminke U, Tardif JC, Taylor A, Vicaut E, Woo KS, Zannad F, Zureik M: Mannheim carotid intimamedia thickness consensus (2004-2006). An update on behalf of the advisory board of the 3rd and 4th watching the risk symposium, 13th and 15th European Stroke Conferences, Mannheim, Germany, 2004, and Brussels, Belgium, 2006. Cerebrovasc Dis, 2007; 23: 75-80","DOI":"10.1159\/000097034"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Tosetto A, Prati P, Baracchini C, Manara R, Rodeghiero F: Age-adjusted reference limits for carotid intima-media thickness as better indicator of vascular risk: Populationbased estimates from the VITA project. J Thromb Haemost, 2005; 3: 1224-1230","DOI":"10.1111\/j.1538-7836.2005.01440.x"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Touboul PJ, Vicaut E, Labreuche J, Acevedo M, Torres V, Ramirez-Martinez J, Vinueza R, Silva H, Champagne B, Hernandez-Hernandez R, Wilson E, Schargrodsky H; CARMELA Study Investigators: Common carotid artery intima-media thickness: the Cardiovascular Risk Factor Multiple Evaluation in Latin America (CARMELA) study results. Cerebrovasc Dis, 2011; 31: 43-50","DOI":"10.1159\/000320264"},{"key":"34","doi-asserted-by":"crossref","unstructured":"35) Folsom AR, Kronmal RA, Detrano RC, O'Leary DH, Bild DE, Bluemke DA, Budoff MJ, Liu K, Shea S, Szklo M, Tracy RP, Watson KE, Burke GL: Coronary artery calcification compared with carotid intima-media thickness in the prediction of cardiovascular disease incidence: the Multi-Ethnic Study of Atherosclerosis (MESA). Arch Intern Med, 2008; 168: 1333-1339","DOI":"10.1001\/archinte.168.12.1333"},{"key":"35","doi-asserted-by":"crossref","unstructured":"36) Polak JF, Pencina MJ, Pencina KM, O'Donnell CJ, Wolf PA, D'Agostino RB: Carotid-wall intima-media thickness and cardiovascular events. N Engl J Med, 2011; 365: 213-221","DOI":"10.1056\/NEJMoa1012592"},{"key":"36","doi-asserted-by":"crossref","unstructured":"37) O'Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK: Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med, 1999; 340: 14-22","DOI":"10.1056\/NEJM199901073400103"},{"key":"37","doi-asserted-by":"crossref","unstructured":"38) Chambless LE, Heiss G, Folsom AR, Rosamond W, Szklo M, Sharrett AR, Clegg LX: Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) study, 1987-1993. Am J Epidemiol, 1997; 146: 483-494","DOI":"10.1093\/oxfordjournals.aje.a009302"},{"key":"38","doi-asserted-by":"crossref","unstructured":"39) Mannami T, Konishi M, Baba S, Nishi N, Terao A: Prevalence of asymptomatic carotid atherosclerotic lesions detected by high-resolution ultrasonography and its relation to cardiovascular risk factors in the general population of a japanese city: the Suita study. Stroke, 1997; 28: 518-525","DOI":"10.1161\/01.STR.28.3.518"},{"key":"39","doi-asserted-by":"crossref","unstructured":"40) Spence JD: Technology insight: Ultrasound measurement of carotid plaque--patient management, genetic research, and therapy evaluation. Nat Clin Pract Neurol, 2006; 2: 611-619","DOI":"10.1038\/ncpneuro0324"},{"key":"40","doi-asserted-by":"crossref","unstructured":"41) Sekikawa A, Ueshima H, Kadowaki T, El-Saed A, Okamura T, Takamiya T, Kashiwagi A, Edmundowicz D, Murata K, Sutton-Tyrrell K, Maegawa H, Evans RW, Kita Y, Kuller LH: Less subclinical atherosclerosis in Japanese men in Japan than in white men in the United States in the post-World War II birth cohort. Am J Epidemiol, 2007; 165: 617-624","DOI":"10.1093\/aje\/kwk053"},{"key":"41","doi-asserted-by":"crossref","unstructured":"42) Polak JF, Pencina MJ, Meisner A, Pencina KM, Brown LS, Wolf PA, D'Agostino RB Sr: Associations of carotid artery intimamedia thickness (IMT) with risk factors and prevalent cardiovascular disease: Comparison of mean common carotid artery IMT with maximum internal carotid artery IMT. J Ultrasound Med, 2010; 29: 1759-1768","DOI":"10.7863\/jum.2010.29.12.1759"},{"key":"42","doi-asserted-by":"crossref","unstructured":"43) Al-Shali K, House AA, Hanley AJ, Khan HM, Harris SB, Mamakeesick M, Zinman B, Fenster A, Spence JD, Hegele RA: Differences between carotid wall morphological phenotypes measured by ultrasound in one, two and three dimensions. Atherosclerosis, 2005; 178: 319-325","DOI":"10.1016\/j.atherosclerosis.2004.08.016"},{"key":"43","doi-asserted-by":"crossref","unstructured":"44) Handa N, Matsumoto M, Maeda H, Hougaku H, Ogawa S, Fukunaga R, Yoneda S, Kimura K, Kamada T: Ultrasonic evaluation of early carotid atherosclerosis. Stroke, 1990; 21: 1567-1572","DOI":"10.1161\/01.STR.21.11.1567"},{"key":"44","doi-asserted-by":"crossref","unstructured":"45) Nomura E, Kohriyama T, Yamaguchi S, Kajikawa H, Nakamura S: Association between carotid atherosclerosis and hemostatic markers in patients with cerebral small artery disease. Blood Coagul Fibrinolysis, 1998; 9: 55-62","DOI":"10.1097\/00001721-199801000-00007"},{"key":"45","doi-asserted-by":"crossref","unstructured":"46) Shrestha I, Takahashi T, Nomura E, Ohtsuki T, Ohshita T, Ueno H, Kohriyama T, Matsumoto M: Association between central systolic blood pressure, white matter lesions in cerebral MRI and carotid atherosclerosis. Hypertens Res, 2009; 32: 869-874","DOI":"10.1038\/hr.2009.121"},{"key":"46","doi-asserted-by":"crossref","unstructured":"47) Hashimoto H, Kitagawa K, Hougaku H, Shimizu Y, Sakaguchi M, Nagai Y, Iyama S, Yamanishi H, Matsumoto M, Hori M: C-reactive protein is an independent predictor of the rate of increase in early carotid atherosclerosis. Circulation, 2001; 104: 63-67","DOI":"10.1161\/hc2601.091705"},{"key":"47","doi-asserted-by":"crossref","unstructured":"48) Polak JF, Shemanski L, O'Leary DH, Lefkowitz D, Price TR, Savage PJ, Brant WE, Reid C: Hypoechoic plaque at US of the carotid artery: An independent risk factor for incident stroke in adults aged 65 years or older. Cardiovascular Health Study. Radiology, 1998; 208: 649-654","DOI":"10.1148\/radiology.208.3.9722841"},{"key":"48","doi-asserted-by":"crossref","unstructured":"49) Gr\u00f8nholdt ML: Ultrasound and lipoproteins as predictors of lipid-rich, rupture-prone plaques in the carotid artery. Arterioscler Thromb Vasc Biol, 1999; 19: 2-13","DOI":"10.1161\/01.ATV.19.1.2"},{"key":"49","doi-asserted-by":"crossref","unstructured":"50) Mathiesen EB, B\u00f8naa KH, Joakimsen O: Echolucent plaques are associated with high risk of ischemic cerebrovascular events in carotid stenosis: The troms\u00f8 study. Circulation, 2001; 103: 2171-2175","DOI":"10.1161\/01.CIR.103.17.2171"},{"key":"50","doi-asserted-by":"crossref","unstructured":"51) Kimura K, Yasaka M, Minematsu K, Wada K, Uchino M, Yonemura K, Ogata J, Yamaguchi T: Oscillating thromboemboli within the extracranial internal carotid artery demonstrated by ultrasonography in patients with acute cardioembolic stroke. Ultrasound Med Biol, 1998; 24: 1121-1124","DOI":"10.1016\/S0301-5629(98)00108-2"},{"key":"51","doi-asserted-by":"crossref","unstructured":"52) Maeda H, Handa N, Matsumoto M, Hougaku H, Ogawa S, Oku N, Itoh T, Moriwaki H, Yoneda S, Kimura K, Kamada T: Carotid lesions detected by B-mode ultrasonography in Takayasu's arteritis: \u201cmacaroni sign\u201d as an indicator of the disease. Ultrasound Med Biol, 1991; 17: 695-701","DOI":"10.1016\/0301-5629(91)90101-2"},{"key":"52","doi-asserted-by":"crossref","unstructured":"53) Yasaka M, Ogata T, Yasumori K, Inoue T, Okada Y: Bottle neck sign of the proximal portion of the internal carotid artery in moyamoya disease. J Ultrasound Med, 2006; 25: 1547-1552; quiz 1553-1544","DOI":"10.7863\/jum.2006.25.12.1547"},{"key":"53","doi-asserted-by":"crossref","unstructured":"54) O'Leary DH, Polak JF, Kronmal RA, Kittner SJ, Bond MG, Wolfson SK Jr, Bommer W, Price TR, Gardin JM, Savage PJ: Distribution and correlates of sonographically detected carotid artery disease in the Cardiovascular Health Study. The CHS Collaborative Research Group. Stroke, 1992; 23: 1752-1760","DOI":"10.1161\/01.STR.23.12.1752"},{"key":"54","doi-asserted-by":"crossref","unstructured":"55) Bots ML, Hofman A, de Bruyn AM, de Jong PT, Grobbee DE: Isolated systolic hypertension and vessel wall thickness of the carotid artery. The Rotterdam Elderly Study. Arterioscler Thromb, 1993; 13: 64-69","DOI":"10.1161\/01.ATV.13.1.64"},{"key":"55","doi-asserted-by":"crossref","unstructured":"56) Naya T, Hosomi N, Ohyama H, Ichihara S, Ban CR, Takahashi T, Taminato T, Feng A, Kohno M, Koziol JA: Smoking, fasting serum insulin, and obesity are the predictors of carotid atherosclerosis in relatively young subjects. Angiology, 2007; 58: 677-684","DOI":"10.1177\/0003319707303589"},{"key":"56","doi-asserted-by":"crossref","unstructured":"57) Nagai Y, Metter EJ, Earley CJ, Kemper MK, Becker LC, Lakatta EG, Fleg JL: Increased carotid artery intimalmedial thickness in asymptomatic older subjects with exercise-induced myocardial ischemia. Circulation, 1998; 98: 1504-1509","DOI":"10.1161\/01.CIR.98.15.1504"},{"key":"57","doi-asserted-by":"crossref","unstructured":"58) Cuspidi C, Mancia G, Ambrosioni E, Pessina A, Trimarco B, Zanchetti A; APROS Investigators: Left ventricular and carotid structure in untreated, uncomplicated essential hypertension: Results from the Assessment Prognostic Risk Observational Survey (APROS). J Hum Hypertens, 2004; 18: 891-896","DOI":"10.1038\/sj.jhh.1001759"},{"key":"58","doi-asserted-by":"crossref","unstructured":"59) Raitakari OT, Juonala M, K\u00e4h\u00f6nen M, Taittonen L, Laitinen T, M\u00e4ki-Torkko N, J\u00e4rvisalo MJ, Uhari M, Jokinen E, R\u00f6nnemaa T, Akerblom HK, Viikari JS.: Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study. JAMA, 2003; 290: 2277-2283","DOI":"10.1001\/jama.290.17.2277"},{"key":"59","doi-asserted-by":"crossref","unstructured":"60) Touboul PJ, Labreuche J, Bruckert E, Schargrodsky H, Prati P, Tosetto A, Hernandez-Hernandez R, Woo KS, Silva H, Vicaut E, Amarenco P: HDL-C, triglycerides and carotid IMT: a meta-analysis of 21,000 patients with automated edge detection IMT measurement. Atherosclerosis, 2014; 232: 65-71","DOI":"10.1016\/j.atherosclerosis.2013.10.011"},{"key":"60","doi-asserted-by":"crossref","unstructured":"61) Brohall G, Od\u00e9n A, Fagerberg B: Carotid artery intimamedia thickness in patients with type 2 diabetes mellitus and impaired glucose tolerance: A systematic review. Diabet Med, 2006; 23: 609-616","DOI":"10.1111\/j.1464-5491.2005.01725.x"},{"key":"61","doi-asserted-by":"crossref","unstructured":"62) Hedblad B, Nilsson P, Janzon L, Berglund G: Relation between insulin resistance and carotid intima-media thickness and stenosis in non-diabetic subjects. Results from a cross-sectional study in Malm\u00f6, Sweden. Diabet Med, 2000; 17: 299-307","DOI":"10.1046\/j.1464-5491.2000.00280.x"},{"key":"62","doi-asserted-by":"crossref","unstructured":"63) Kozakova M, Natali A, Dekker J, Beck-Nielsen H, Laakso M, Nilsson P, Balkau B, Ferrannini E; RISC Investigators: Insulin sensitivity and carotid intimamedia thickness: Relationship between insulin sensitivity and cardiovascular risk study. Arterioscler Thromb Vasc Biol, 2013; 33: 1409-1417","DOI":"10.1161\/ATVBAHA.112.300948"},{"key":"63","doi-asserted-by":"crossref","unstructured":"64) Lee YH, Shin MH, Kweon SS, Nam HS, Park KS, Choi JS, Choi SW, Kim HY, Oh GJ, Ahn HR, Oh HS, Jeong SK: Normative and mean carotid intima-media thickness values according to metabolic syndrome in Koreans: The Namwon study. Atherosclerosis, 2014; 234: 230-236","DOI":"10.1016\/j.atherosclerosis.2014.02.023"},{"key":"64","doi-asserted-by":"crossref","unstructured":"65) Fan AZ: Metabolic syndrome and progression of atherosclerosis among middle-aged US adults. J Atheroscler Thromb, 2006; 13: 46-54","DOI":"10.5551\/jat.13.46"},{"key":"65","doi-asserted-by":"crossref","unstructured":"66) Iglseder B, Cip P, Malaimare L, Ladurner G, Paulweber B: The metabolic syndrome is a stronger risk factor for early carotid atherosclerosis in women than in men. Stroke, 2005; 36: 1212-1217","DOI":"10.1161\/01.STR.0000166196.31227.91"},{"key":"66","doi-asserted-by":"crossref","unstructured":"67) Danesh J, Wheeler JG, Hirschfield GM, Eda S, Eiriksdottir G, Rumley A, Lowe GD, Pepys MB, Gudnason V: C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med, 2004; 350: 1387- 1397","DOI":"10.1056\/NEJMoa032804"},{"key":"67","doi-asserted-by":"crossref","unstructured":"68) Ridker PM, Buring JE, Cook NR, Rifai N: C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: An 8-year follow-up of 14 719 initially healthy American women. Circulation, 2003; 107: 391-397","DOI":"10.1161\/01.CIR.0000055014.62083.05"},{"key":"68","doi-asserted-by":"crossref","unstructured":"69) Ridker PM, Cook N: Clinical usefulness of very high and very low levels of C-reactive protein across the full range of Framingham Risk Scores. Circulation, 2004; 109: 1955-1959","DOI":"10.1161\/01.CIR.0000125690.80303.A8"},{"key":"69","doi-asserted-by":"crossref","unstructured":"70) Sitzer M, Markus HS, Mendall MA, Liehr R, Knorr U, Steinmetz H: C-reactive protein and carotid intimal medial thickness in a community population. J Cardiovasc Risk, 2002; 9: 97-103","DOI":"10.1177\/174182670200900205"},{"key":"70","doi-asserted-by":"crossref","unstructured":"71) Baldassarre D, De Jong A, Amato M, Werba JP, Castelnuovo S, Frigerio B, Veglia F, Tremoli E, Sirtori CR: Carotid intima-media thickness and markers of inflammation, endothelial damage and hemostasis. Ann Med, 2008; 40: 21-44","DOI":"10.1080\/07853890701645399"},{"key":"71","doi-asserted-by":"crossref","unstructured":"72) Ernst E, Resch KL: Fibrinogen as a cardiovascular risk factor: A meta-analysis and review of the literature. Ann Intern Med, 1993; 118: 956-963","DOI":"10.7326\/0003-4819-118-12-199306150-00008"},{"key":"72","doi-asserted-by":"crossref","unstructured":"73) Mart\u00ednez-Vila E, P\u00e1ramo JA, Beloqui O, Orbe J, Irimia P, Colina I, Monreal I, Benito A, Barba J, Zubieta JL, Diez J: Independent association of fibrinogen with carotid intima-media thickness in asymptomatic subjects. Cerebrovasc Dis, 2003; 16: 356-362","DOI":"10.1159\/000072557"},{"key":"73","unstructured":"74) P\u00e1ramo JA, Beloqui O, Roncal C, Benito A, Orbe J: Validation of plasma fibrinogen as a marker of carotid atherosclerosis in subjects free of clinical cardiovascular disease. Haematologica, 2004; 89: 1226-1231"},{"key":"74","doi-asserted-by":"crossref","unstructured":"75) Hulthe J, Fagerberg B: Circulating oxidized LDL is associated with subclinical atherosclerosis development and inflammatory cytokines (AIR Study). Arterioscler Thromb Vasc Biol, 2002; 22: 1162-1167","DOI":"10.1161\/01.ATV.0000021150.63480.CD"},{"key":"75","doi-asserted-by":"crossref","unstructured":"76) Holvoet P, Jenny NS, Schreiner PJ, Tracy RP, Jacobs DR, Atherosclerosis M-ESo: The relationship between oxidized LDL and other cardiovascular risk factors and subclinical CVD in different ethnic groups: the MultiEthnic Study of Atherosclerosis (MESA). Atherosclerosis, 2007; 194: 245-252","DOI":"10.1016\/j.atherosclerosis.2006.08.002"},{"key":"76","doi-asserted-by":"crossref","unstructured":"77) Liu ML, Ylitalo K, Salonen R, Salonen JT, Taskinen MR: Circulating oxidized low-density lipoprotein and its association with carotid intima-media thickness in asymptomatic members of familial combined hyperlipidemia families. Arterioscler Thromb Vasc Biol, 2004; 24: 1492-1497","DOI":"10.1161\/01.ATV.0000135982.60383.48"},{"key":"77","doi-asserted-by":"crossref","unstructured":"78) Tanaga K, Bujo H, Inoue M, Mikami K, Kotani K, Takahashi K, Kanno T, Saito Y: Increased circulating malondialdehyde- modified LDL levels in patients with coronary artery diseases and their association with peak sizes of LDL particles. Arterioscler Thromb Vasc Biol, 2002; 22: 662-666","DOI":"10.1161\/01.ATV.0000012351.63938.84"},{"key":"78","doi-asserted-by":"crossref","unstructured":"79) Okamura T, Sekikawa A, Sawamura T, Kadowaki T, Barinas- Mitchell E, Mackey RH, Kadota A, Evans RW, Edmundowicz D, Higashiyama A, Nakamura Y, Abbott RD, Miura K, Fujiyoshi A, Fujita Y, Murakami Y, Miyamatsu N, Kakino A, Maegawa H, Murata K, Horie M, Mitsunami K, Kashiwagi A, Kuller LH, Ueshima H; ERA JUMP Study Group: Lox-1 ligands containing apolipoprotein B and carotid intima-media thickness in middle-aged community-dwelling US caucasian and Japanese men. Atherosclerosis, 2013; 229: 240-245","DOI":"10.1016\/j.atherosclerosis.2013.04.023"},{"key":"79","doi-asserted-by":"crossref","unstructured":"80) Rundek T, Arif H, Boden-Albala B, Elkind MS, Paik MC, Sacco RL: Carotid plaque, a subclinical precursor of vascular events: the Northern Manhattan Study. Neurology, 2008; 70: 1200-1207","DOI":"10.1212\/01.wnl.0000303969.63165.34"},{"key":"80","doi-asserted-by":"crossref","unstructured":"81) Hosomi N, Ohyama H, Takahashi T, Shinomiya K, Naya T, Ban CR, Osaka K, Kohno M, Koziol JA: Plasma adrenomedullin and carotid atherosclerosis in atherothrombotic ischemic stroke. J Hypertens, 2004; 22: 1945-1951","DOI":"10.1097\/00004872-200410000-00017"},{"key":"81","doi-asserted-by":"crossref","unstructured":"82) Sugimoto T, Hosomi N, Nezu T, Takahashi T, Aoki S, Takeda I, Mukai T, Ochi K, Kitamura T, Ohtsuki T, Matsumoto M: CD34+\/CD144+ circulating endothelial cells as an indicator of carotid atherosclerosis. J Stroke Cerebrovasc Dis, 2015; 24: 583-590","DOI":"10.1016\/j.jstrokecerebrovasdis.2014.10.001"},{"key":"82","doi-asserted-by":"crossref","unstructured":"83) Bots ML, Groenewegen KA, Anderson TJ, Britton AR, Dekker JM, Engstr\u00f6m G, Evans GW, de Graaf J, Grobbee DE, Hedblad B, Hofman A, Holewijn S, Ikeda A, Kavousi M, Kitagawa K, Kitamura A, Ikram MA, Lonn EM, Lorenz MW, Mathiesen EB, Nijpels G, Okazaki S, O'Leary DH, Polak JF, Price JF, Robertson C, Rembold CM, Rosvall M, Rundek T, Salonen JT, Sitzer M, Stehouwer CD, Franco OH, Peters SA, den Ruijter HM.et al.: Common carotid intima-media thickness measurements do not improve cardiovascular risk prediction in individuals with elevated blood pressure: the USE-IMT collaboration. Hypertension, 2014; 63: 1173-1181","DOI":"10.1161\/HYPERTENSIONAHA.113.02683"},{"key":"83","doi-asserted-by":"crossref","unstructured":"84) Den Ruijter HM, Peters SA, Groenewegen KA, Anderson TJ, Britton AR, Dekker JM, Engstr\u00f6m G, Eijkemans MJ, Evans GW, de Graaf J, Grobbee DE, Hedblad B, Hofman A, Holewijn S, Ikeda A, Kavousi M, Kitagawa K, Kitamura A, Koffijberg H, Ikram MA, Lonn EM, Lorenz MW, Mathiesen EB, Nijpels G, Okazaki S, O'Leary DH, Polak JF, Price JF, Robertson C, Rembold CM, Rosvall M, Rundek T, Salonen JT, Sitzer M, Stehouwer CD, Witteman JC, Moons KG, Bots ML: Common carotid intima-media thickness does not add to Framingham risk score in individuals with diabetes mellitus: the USEIMT initiative. Diabetologia, 2013; 56: 1494-1502","DOI":"10.1007\/s00125-013-2898-9"},{"key":"84","doi-asserted-by":"crossref","unstructured":"85) Polak JF, Szklo M, Kronmal RA, Burke GL, Shea S, Zavodni AE, O'Leary DH: The value of carotid artery plaque and intima-media thickness for incident cardiovascular disease: The multi-ethnic study of atherosclero sis.J Am Heart Assoc, 2013; 2: e000087","DOI":"10.1161\/JAHA.113.000087"},{"key":"85","doi-asserted-by":"crossref","unstructured":"86) Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K: Absolute risk of cardiovascular disease and lipid management targets. J Atheroscler Thromb, 2013; 20: 689-697","DOI":"10.5551\/jat.17392"},{"key":"86","doi-asserted-by":"crossref","unstructured":"87) NIPPON DATA80 Research Group: Risk assessment chart for death from cardiovascular disease based on a 19-year follow-up study of a Japanese representative population. Circ J, 2006; 70: 1249-1255","DOI":"10.1253\/circj.70.1249"},{"key":"87","doi-asserted-by":"crossref","unstructured":"88) Kadota A, Miura K, Okamura T, Fujiyoshi A, Ohkubo T, Kadowaki T, Takashima N, Hisamatsu T, Nakamura Y, Kasagi F, Maegawa H, Kashiwagi A, Ueshima H; SESSA Research Group; NIPPON DATA80\/90 Research Group: Carotid intima-media thickness and plaque in apparently healthy japanese individuals with an estimated 10-year absolute risk of CAD death according to the Japan Atherosclerosis Society (JAS) guidelines 2012: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA). J Atheroscler Thromb, 2013; 20: 755-766","DOI":"10.5551\/jat.17244"},{"key":"88","doi-asserted-by":"crossref","unstructured":"89) Fujihara K, Suzuki H, Sato A, Ishizu T, Kodama S, Heianza Y, Saito K, Iwasaki H, Kobayashi K, Yatoh S, Takahashi A, Yahagi N, Sone H, Shimano H: Comparison of the Framingham risk score, UK Prospective Diabetes Study (UKPDS) Risk Engine, Japanese Atherosclerosis Longitudinal Study- Existing Cohorts Combine (JALS-ECC) and maximum carotid intima-media thickness for predicting coronary artery stenosis in patients with asymptomatic type 2 diabetes. J Atheroscler Thromb, 2014; 21: 799-815","DOI":"10.5551\/jat.20487"},{"key":"89","doi-asserted-by":"crossref","unstructured":"90) Daida H, Nohara R, Hata M, Kaku K, Kawamori R, Kishimoto J, Kurabayashi M, Masuda I, Sakuma I, Yamazaki T, Yokoi H, Yoshida M; Justification for Atherosclerosis Regression Treatment (JART) Investigators: Can intensive lipid-lowering therapy improve the carotid intima-media thickness in japanese subjects under primary prevention for cardiovascular disease?: The JART and JART extension subanalysis. J Atheroscler Thromb, 2014; 21: 739-754","DOI":"10.5551\/jat.19109"},{"key":"90","doi-asserted-by":"crossref","unstructured":"91) Ishigaki Y, Kono S, Katagiri H, Oka Y, Oikawa S, investigators N: Elevation of HDL-C in response to statin treatment is involved in the regression of carotid atherosclerosis. J Atheroscler Thromb, 2014; 21: 1055-1065","DOI":"10.5551\/jat.22095"},{"key":"91","doi-asserted-by":"crossref","unstructured":"92) Amarenco P, Labreuche J, Lavall\u00e9e P, Touboul PJ: Statins in stroke prevention and carotid atherosclerosis: Systematic review and up-to-date meta-analysis. Stroke, 2004; 35: 2902-2909","DOI":"10.1161\/01.STR.0000147965.52712.fa"},{"key":"92","doi-asserted-by":"crossref","unstructured":"93) Huang Y, Li W, Dong L, Li R, Wu Y: Effect of statin therapy on the progression of common carotid artery intima-media thickness: An updated systematic review and meta-analysis of randomized controlled trials. J Atheroscler Thromb, 2013; 20: 108-121","DOI":"10.5551\/jat.14001"},{"key":"93","doi-asserted-by":"crossref","unstructured":"94) Katakami N, Kim YS, Kawamori R, Yamasaki Y: The phosphodiesterase inhibitor cilostazol induces regression of carotid atherosclerosis in subjects with type 2 diabetes mellitus: principal results of the Diabetic Atherosclerosis Prevention by Cilostazol (DAPC) study: a randomized trial. Circulation, 2010; 121: 2584-2591","DOI":"10.1161\/CIRCULATIONAHA.109.892414"},{"key":"94","doi-asserted-by":"crossref","unstructured":"95) Wang JG, Staessen JA, Li Y, Van Bortel LM, Nawrot T, Fagard R, Messerli FH, Safar M: Carotid intima-media thickness and antihypertensive treatment: A meta-analysis of randomized controlled trials. Stroke, 2006; 37: 1933-1940","DOI":"10.1161\/01.STR.0000227223.90239.13"},{"key":"95","doi-asserted-by":"crossref","unstructured":"96) Geng DF, Jin DM, Wu W, Fang C, Wang JF: Effect of alpha-glucosidase inhibitors on the progression of carotid intima-media thickness: A meta-analysis of randomized controlled trials. Atherosclerosis, 2011; 218: 214-219","DOI":"10.1016\/j.atherosclerosis.2011.05.004"},{"key":"96","doi-asserted-by":"crossref","unstructured":"97) van der Meer IM, Bots ML, Hofman A, del Sol AI, van der Kuip DA, Witteman JC: Predictive value of noninvasive measures of atherosclerosis for incident myocardial infarction: the Rotterdam Study. Circulation, 2004; 109: 1089-1094","DOI":"10.1161\/01.CIR.0000120708.59903.1B"},{"key":"97","doi-asserted-by":"crossref","unstructured":"98) Johnsen SH, Mathiesen EB, Joakimsen O, Stensland E, Wilsgaard T, L\u00f8chen ML, et al.: Carotid atherosclerosis is a stronger predictor of myocardial infarction in women than in men: a 6-year follow-up study of 6226 persons: the Troms\u00f8 Study. Stroke, 2007; 38: 2873-2880","DOI":"10.1161\/STROKEAHA.107.487264"},{"key":"98","doi-asserted-by":"crossref","unstructured":"99) Hollander M, Hak AE, Koudstaal PJ, Bots ML, Grobbee DE, Hofman A, Witteman JC, Breteler MM: Comparison between measures of atherosclerosis and risk of stroke: the Rotterdam Study. Stroke, 2003; 34: 2367-2372","DOI":"10.1161\/01.STR.0000091393.32060.0E"},{"key":"99","doi-asserted-by":"crossref","unstructured":"100) Mathiesen EB, Johnsen SH, Wilsgaard T, B\u00f8naa KH, L\u00f8chen ML, Nj\u00f8lstad I: Carotid plaque area and intimamedia thickness in prediction of first-ever ischemic stroke: A 10-year follow-up of 6584 men and women: the Troms\u00f8 Study. Stroke, 2011; 42: 972-978","DOI":"10.1161\/STROKEAHA.110.589754"},{"key":"100","doi-asserted-by":"crossref","unstructured":"101) Kitamura A, Iso H, Imano H, Ohira T, Okada T, Sato S, et al.: Carotid intima-media thickness and plaque characteristics as a risk factor for stroke in Japanese elderly men. Stroke, 2004; 35: 2788-2794","DOI":"10.1161\/01.STR.0000147723.52033.9e"},{"key":"101","doi-asserted-by":"crossref","unstructured":"102) Rosvall M, Janzon L, Berglund G, Engstr\u00f6m G, Hedblad B: Incident coronary events and case fatality in relation to common carotid intima-media thickness. J Intern Med, 2005; 257: 430-437","DOI":"10.1111\/j.1365-2796.2005.01485.x"},{"key":"102","doi-asserted-by":"crossref","unstructured":"103) Nambi V, Chambless L, Folsom AR, He M, Hu Y, Mosley T, Volcik K, Boerwinkle E, Ballantyne CM: Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk In Communities) study. J Am Coll Cardiol, 2010; 55: 1600-1607","DOI":"10.1016\/j.jacc.2009.11.075"},{"key":"103","doi-asserted-by":"crossref","unstructured":"104) Hofman A, van Duijn CM, Franco OH, Ikram MA, Janssen HL, Klaver CC, Kuipers EJ, Nijsten TE, Stricker BH, Tiemeier H, Uitterlinden AG, Vernooij MW, Witteman JC: The Rotterdam Study: 2012 objectives and design update. Eur J Epidemiol, 2011; 26: 657-686","DOI":"10.1007\/s10654-011-9610-5"},{"key":"104","doi-asserted-by":"crossref","unstructured":"105) Ali YS, Rembold KE, Weaver B, Wills MB, Tatar S, Ayers CR, Rembold CM: Prediction of major adverse cardiovascular events by age-normalized carotid intimal medial thickness. Atherosclerosis, 2006; 187: 186-190","DOI":"10.1016\/j.atherosclerosis.2005.09.003"},{"key":"105","doi-asserted-by":"crossref","unstructured":"106) Anderson TJ, Charbonneau F, Title LM, Buithieu J, Rose MS, Conradson H, Hildebrand K, Fung M, Verma S, Lonn EM: Microvascular function predicts cardiovascular events in primary prevention: Long-term results from the Firefighters and Their Endothelium (FATE) study. Circulation, 2011; 123: 163-169","DOI":"10.1161\/CIRCULATIONAHA.110.953653"},{"key":"106","doi-asserted-by":"crossref","unstructured":"107) Henry RM, Kostense PJ, Spijkerman AM, Dekker JM, Nijpels G, Heine RJ, Kamp O, Westerhof N, Bouter LM, Stehouwer CD; Hoorn Study: Arterial stiffness increases with deteriorating glucose tolerance status: the Hoorn study. Circulation, 2003; 107: 2089-2095","DOI":"10.1161\/01.CIR.0000065222.34933.FC"},{"key":"107","doi-asserted-by":"crossref","unstructured":"108) Rosvall M, Ostergren PO, Hedblad B, Isacsson SO, Janzon L, Berglund G: Occupational status, educational level, and the prevalence of carotid atherosclerosis in a general population sample of middle-aged Swedish men and women: Results from the Malm\u00f6 Diet and Cancer Study. Am J Epidemiol, 2000; 152: 334-346","DOI":"10.1093\/aje\/152.4.334"},{"key":"108","doi-asserted-by":"crossref","unstructured":"109) Holewijn S, den Heijer M, Swinkels DW, Stalenhoef AF, de Graaf J: The metabolic syndrome and its traits as risk factors for subclinical atherosclerosis. J Clin Endocrinol Metab, 2009; 94: 2893-2899","DOI":"10.1210\/jc.2009-0084"},{"key":"109","doi-asserted-by":"crossref","unstructured":"110) Kitagawa K, Hougaku H, Yamagami H, Hashimoto H, Itoh T, Shimizu Y, Takahashi D, Murata S, Seike Y, Kondo K, Hoshi T, Furukado S, Abe Y, Yagita Y, Sakaguchi M, Tagaya M, Etani H, Fukunaga R, Nagai Y, Matsumoto M, Hori M; OSACA2 Study Group: Carotid intima-media thickness and risk of cardiovascular events in high-risk patients. Results of the Osaka Follow-Up Study for Carotid Atherosclerosis 2 (OSACA2 study). Cerebrovasc Dis, 2007; 24: 35-42","DOI":"10.1159\/000103114"},{"key":"110","doi-asserted-by":"crossref","unstructured":"111) Xie W, Liang L, Zhao L, Shi P, Yang Y, Xie G, Huo Y, Wu Y: Combination of carotid intima-media thickness and plaque for better predicting risk of ischaemic cardiovascular events. Heart, 2011; 97: 1326-1331","DOI":"10.1136\/hrt.2011.223032"},{"key":"111","doi-asserted-by":"crossref","unstructured":"112) Chambless LE, Folsom AR, Sharrett AR, Sorlie P, Couper D, Szklo M, Nieto FJ: Coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC) study. J Clin Epidemiol, 2003; 56: 880-890","DOI":"10.1016\/S0895-4356(03)00055-6"},{"key":"112","doi-asserted-by":"crossref","unstructured":"113) Lorenz MW, Schaefer C, Steinmetz H, Sitzer M: Is carotid intima media thickness useful for individual prediction of cardiovascular risk? Ten-year results from the Carotid Atherosclerosis Progression Study (CAPS). Eur Heart J, 2010; 31: 2041-2048","DOI":"10.1093\/eurheartj\/ehq189"}],"container-title":["Journal of Atherosclerosis and Thrombosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jat\/23\/1\/23_31989\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,31]],"date-time":"2019-08-31T09:25:32Z","timestamp":1567243532000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jat\/23\/1\/23_31989\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":112,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.5551\/jat.31989","relation":{},"ISSN":["1340-3478","1880-3873"],"issn-type":[{"value":"1340-3478","type":"print"},{"value":"1880-3873","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}