{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T14:23:48Z","timestamp":1775226228634,"version":"3.50.1"},"reference-count":20,"publisher":"Japan Atherosclerosis Society","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAT","J Atheroscler Thromb"],"published-print":{"date-parts":[[2020,3,1]]},"DOI":"10.5551\/jat.49700","type":"journal-article","created":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T22:02:37Z","timestamp":1565215357000},"page":"215-225","source":"Crossref","is-referenced-by-count":18,"title":["Total Thrombus-Formation Analysis System can Predict 1-Year Bleeding Events in Patients with Coronary Artery Disease"],"prefix":"10.5551","volume":"27","author":[{"given":"Tatsuro","family":"Mitsuse","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Kaikita","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanobu","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Oimatsu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhiro","family":"Nakanishi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miwa","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichiro","family":"Arima","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Sueta","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satomi","family":"Iwashita","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichiro","family":"Fujisue","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisanori","family":"Kanazawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiji","family":"Takashio","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Araki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Usuku","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiichiro","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirofumi","family":"Soejima","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Tsujita","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Sciences, and Center for Metabolic Regulation of Healthy Aging Kumamoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3489","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Mehran R, Pocock S, Nikolsky E, Dangas GD, Clayton T, Claessen BE, Caixeta A, Feit F, Manoukian SV, White H, Bertrand M, Ohman EM, Parise H, Lansky AJ, Lincoff AM, Stone GW. Impact of bleeding on mortality after percutaneous coronary intervention results from a patientlevel pooled analysis of the REPLACE-2 (randomized evaluation of PCI linking angiomax to reduced clinical events), ACUITY (acute catheterization and urgent intervention triage strategy), and HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trials. JACC Cardiovasc Interv, 2011; 4: 654-664","DOI":"10.1016\/j.jcin.2011.02.011"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Genereux P, Giustino G, Witzenbichler B, Weisz G, Stuckey TD, Rinaldi MJ, Neumann FJ, Metzger DC, Henry TD, Cox DA, Duffy PL, Mazzaferri E, Yadav M, Francese DP, Palmerini T,Kirtane AJ, Litherland C, Mehran R, Stone GW. Incidence, predictors, and impact of post-discharge bleeding after percutaneous coronary intervention. J Am Coll Cardiol, 2015; 66: 1036-1045","DOI":"10.1016\/j.jacc.2015.06.1323"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Verheugt FW, Steinhubl SR, Hamon M, Darius H, Steg PG, Valgimigli M, Marso SP, Rao SV, Gershlick AH, Lincoff AM, Mehran R, Stone GW. Incidence, prognostic impact, and influence of antithrombotic therapy on access and nonaccess site bleeding in percutaneous coronary intervention. JACC Cardiovasc Interv, 2011; 4: 191-197","DOI":"10.1016\/j.jcin.2010.10.011"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Eikelboom JW, Mehta SR, Anand SS, Xie C, Fox KA, Yusuf S. Adverse impact of bleeding on prognosis in patients with acute coronary syndromes. Circulation, 2006; 114: 774-782","DOI":"10.1161\/CIRCULATIONAHA.106.612812"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Hamon M, Lemesle G, Tricot O, Meurice T, Deneve M, Dujardin X, Brufau JM, Bera J, Lamblin N, Bauters C. Incidence, source, determinants, and prognostic impact of major bleeding in outpatients with stable coronary artery disease. J Am Coll Cardiol, 2014; 64: 1430-1436","DOI":"10.1016\/j.jacc.2014.07.957"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Rubboli A, Colletta M, Herzfeld J, Sangiorgio P, Di Pasquale G. Periprocedural and medium-term antithrombotic strategies in patients with an indication for long-term anticoagulation undergoing coronary angiography and intervention. Coronary Artery Dis, 2007; 18: 193-199","DOI":"10.1097\/MCA.0b013e328012a964"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Wang TY, Robinson LA, Ou FS, Roe MT, Ohman EM, Gibler WB, Smith SC Jr, Peterson ED, Becker RC. Discharge antithrombotic strategies among patients with acute coronary syndrome previously on warfarin anticoagulation: physician practice in the CRUSADE registry. Am Heart J, 2008; 155: 361-368","DOI":"10.1016\/j.ahj.2007.09.003"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Perez-Gomez F, Alegria E, Berjon J, Iriarte JA, Zumalde J, Salvador A, Mataix L; NASPEAF Investigators. Comparative effects of antiplatelet, anticoagulant, or combined therapy in patients with valvular and nonvalvular atrial fibrillation: a randomized multicenter study. J Am Coll Cardiol, 2004; 44: 1557-1566","DOI":"10.1016\/j.jacc.2004.05.084"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Paikin JS, Wright DS, Crowther MA, Mehta SR, Eikelboom JW. Triple antithrombotic therapy in patients with atrial fibrillation and coronary artery stents. Circulation, 2010; 121: 2067-2070","DOI":"10.1161\/CIRCULATIONAHA.109.924944"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Yoshikawa Y, Shiomi H, Watanabe H, Natsuaki M, Kondo H, Tamura T, Nakagawa Y, Morimoto T, Kimura T. Validating utility of dual antiplatelet therapy score in a large pooled cohort from 3 Japanese percutaneous coronary intervention studies. Circulation, 2018; 137: 551-562","DOI":"10.1161\/CIRCULATIONAHA.117.028924"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Lip GY, Windecker S, Huber K, Kirchhof P, Marin F, Ten Berg JM, Haeusler KG, Boriani G, Capodanno D, Gilard M, Zeymer U, Lane D; Document Reviewers, Storey RF, Bueno H, Collet JP, Fauchier L, Halvorsen S, Lettino M, Morais J, Mueller C, Potpara TS, Rasmussen LH,Rubboli A, Tamargo J, Valgimigli M, Zamorano JL. Management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and\/or undergoing percutaneous coronary or valve interventions: A joint consensus document of the European Society of Cardiology Working Group on Thrombosis, European Heart Rhythm Association (EHRA), European Association of Percutaneous Cardiovascular Interventions (EAPCI) and European Association of Acute Cardiac Care (ACCA) endorsed by the Heart Rhythm Society (HRS) and Asia-Pacific Heart Rhythm Society (APHRS). Eur Heart J, 2014; 35: 3155-3179","DOI":"10.1093\/eurheartj\/ehu298"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Hosokawa K, Ohnishi T, Sameshima H, Miura N, Ito T, Koide T, Maruyama I. Analysing responses to aspirin and clopidogrel by measuring platelet thrombus formation under arterial flow conditions. Thromb Haemost, 2013; 109: 102-111","DOI":"10.1160\/TH12-06-0441"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Hosokawa K, Ohnishi T, Kondo T, Fukasawa M, Koide T, Maruyama I, Tanaka KA. A novel automated microchip flow-chamber system to quantitatively evaluate thrombus formation and antithrombotic agents under blood flow conditions. J Thromb Haemost, 2011; 9: 2029-2037","DOI":"10.1111\/j.1538-7836.2011.04464.x"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Sueta D, Kaikita K, Okamoto N, Arima Y, Ishii M, Ito M, Oimatsu Y, Iwashita S, Takahashi A, Nakamura E, Hokimoto S, Mizuta H, Ogawa H. A novel quantitative assessment of whole blood thrombogenicity in patients treated with a non-vitamin K oral anticoagulant. Int J Cardiol, 2015; 197: 98-100","DOI":"10.1016\/j.ijcard.2015.06.041"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Ito M, Kaikita K, Sueta D, Ishii M, Oimatsu Y, Arima Y, Iwashita S, Takahashi A, Hoshiyama T, Kanazawa H, Sakamoto K, Yamamoto E, Tsujita K, Yamamuro M, Kojima S,Hokimoto S, Yamabe H and Ogawa H. Total Thrombus-Formation Analysis System (T-TAS) can predict periprocedural bleeding events in patients undergoing catheter ablation for atrial fibrillation. J Am Heart Assoc, 2016; 5:e002744","DOI":"10.1161\/JAHA.115.002744"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Arima Y, Kaikita K, Ishii M, Ito M, Sueta D, Oimatsu Y, Sakamoto K, Tsujita K, Kojima S, Nakagawa K, Hokimoto S, Ogawa H. Assessment of platelet-derived thrombogenicity with the total thrombus-formation analysis system in coronary artery disease patients receiving antiplatelet therapy. J Thromb Haemost, 2016; 14: 850-859","DOI":"10.1111\/jth.13256"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Oimatsu Y, Kaikita K, Ishii M, Mitsuse T, Ito M, Arima Y, Sueta D, Takahashi A, Iwashita S, Yamamoto E, Kojima S, Hokimoto S, Tsujita K. Total thrombus-formation analysis system predicts periprocedural bleeding events in patients with coronary artery disease undergoing percutaneous coronary intervention. J Am Heart Assoc, 2017; 6: e005263","DOI":"10.1161\/JAHA.116.005263"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Wallentin L, Becker RC, Budaj A, Cannon CP, Emanuelsson H, Held C, Horrow J, Husted S, James S, Katus H, Mahaffey KW, Scirica BM, Skene A, Steg PG, Storey RF, Harrington RA; PLATO Investigators, Freij A, Thors\u00e9n M. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. New Engl J Med, 2009; 361: 1045-1057","DOI":"10.1056\/NEJMoa0904327"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Steg PG, Huber K, Andreotti F, Arnesen H, Atar D, Badimon L, Bassand JP, De Caterina R, Eikelboom JA, Gulba D, Hamon M, Helft G, Fox KA, Kristensen SD, Rao SV, Verheugt FW, Widimsky P, Zeymer U, Collet JP. Bleeding in acute coronary syndromes and percutaneous coronary interventions: position paper by the Working Group on Thrombosis of the European Society of Cardiology. Eur Heart J, 2011; 32: 1854-1864","DOI":"10.1093\/eurheartj\/ehr204"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Kinnaird TD, Stabile E, Mintz GS, Lee CW, Canos DA, Gevorkian N, Pinnow EE, Kent KM, Pichard AD, Satler LF, Weissman NJ, Lindsay J, Fuchs S. Incidence, predictors, and prognostic implications of bleeding and blood transfusion following percutaneous coronary interventions. Am J Cardiol, 2003; 92: 930-935","DOI":"10.1016\/S0002-9149(03)00972-X"}],"container-title":["Journal of Atherosclerosis and Thrombosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jat\/27\/3\/27_49700\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,7]],"date-time":"2020-03-07T03:18:08Z","timestamp":1583551088000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jat\/27\/3\/27_49700\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,1]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.5551\/jat.49700","relation":{},"ISSN":["1340-3478","1880-3873"],"issn-type":[{"value":"1340-3478","type":"print"},{"value":"1880-3873","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,1]]}}}