{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T07:38:28Z","timestamp":1772264308228,"version":"3.50.1"},"reference-count":20,"publisher":"Japan Atherosclerosis Society","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAT","J Atheroscler Thromb"],"published-print":{"date-parts":[[2025,11,1]]},"DOI":"10.5551\/jat.65650","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T18:08:19Z","timestamp":1748023699000},"page":"1425-1433","source":"Crossref","is-referenced-by-count":0,"title":["Serum Total Cholesterol and Fatal Subarachnoid Hemorrhage in 120,000 Japanese: A Pooled Analysis of Data from 12 Cohorts"],"prefix":"10.5551","volume":"32","author":[{"given":"Atsushi","family":"Satoh","sequence":"first","affiliation":[{"name":"Laboratory of Epidemiology and Prevention, Kobe Pharmaceutical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisatomi","family":"Arima","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Public Health, Fukuoka University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachiko","family":"Tanaka-Mizuno","sequence":"additional","affiliation":[{"name":"Laboratory of Epidemiology and Prevention, Kobe Pharmaceutical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Fujiyoshi","sequence":"additional","affiliation":[{"name":"Department of Hygiene, Wakayama Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Kadota","sequence":"additional","affiliation":[{"name":"NCD Epidemiology Research Center, Shiga University of Medical Science"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuyuki","family":"Miura","sequence":"additional","affiliation":[{"name":"NCD Epidemiology Research Center, Shiga University of Medical Science"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotsugu","family":"Ueshima","sequence":"additional","affiliation":[{"name":"NCD Epidemiology Research Center, Shiga University of Medical Science"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonori","family":"Okamura","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Public Health, Keio University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitaka","family":"Murakami","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics, School of Medicine, Toho University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"EPOCH JAPAN Research Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3489","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) de Rooij NK, Linn FH, van der Plas JA, Algra A, Rinkel GJ. Incidence of subarachnoid haemorrhage: A systematic review with emphasis on region, age, gender and time trends. J Neurol Neurosurg Psychiatry, 2007; 78: 1365-1372","DOI":"10.1136\/jnnp.2007.117655"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Suzuki K, Izumi M, Sakamoto T, Hayashi M. Blood pressure and total cholesterol level are critical risks especially for hemorrhagic stroke in akita, japan. Cerebrovasc Dis, 2011; 31: 100-106","DOI":"10.1159\/000321506"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Takashima N, Arima H, Kita Y, Fujii T, Miyamatsu N, Komori M, et al. Incidence, management and short-term outcome of stroke in a general population of 1.4 million japanese- shiga stroke registry. Circ J, 2017; 81: 1636-1646","DOI":"10.1253\/circj.CJ-17-0177"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Feigin VL, Lawes CMM, Bennett DA, Barker-Collo SL, Parag V. Worldwide stroke incidence and early case fatality reported in 56 population-based studies: A systematic review. The Lancet Neurology, 2009; 8: 355-369","DOI":"10.1016\/S1474-4422(09)70025-0"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Etminan N, Chang HS, Hackenberg K, de Rooij NK, Vergouwen MDI, Rinkel GJE, et al. Worldwide incidence of aneurysmal subarachnoid hemorrhage according to region, time period, blood pressure, and smoking prevalence in the population: A systematic review and meta-analysis. JAMA Neurol, 2019; 76: 588-597","DOI":"10.1001\/jamaneurol.2019.0006"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Wang X, Dong Y, Qi X, Huang C, Hou L. Cholesterol levels and risk of hemorrhagic stroke: A systematic review and meta-analysis. Stroke, 2013; 44: 1833-1839","DOI":"10.1161\/STROKEAHA.113.001326"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Ueshima H, Iida M, Shimamoto T, Konishi M, Tsujioka K, Tanigaki M, et al. Multivariate analysis of risk factors for stroke. Eight-year follow-up study of farming villages in akita, japan. Preventive medicine, 1980; 9: 722-740","DOI":"10.1016\/0091-7435(80)90017-1"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Iso H, Jacobs DR, Wentworth D, Neaton JD, Cohen JD. Serum cholesterol levels and six-year mortality from stroke in 350,977 men screened for the multiple risk factor intervention trial. New England Journal of Medicine, 1989; 320: 904-910","DOI":"10.1056\/NEJM198904063201405"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Yano K, Reed DM, MacLean CJ. Serum cholesterol and hemorrhagic stroke in the honolulu heart program. Stroke, 1989; 20: 1460-1465","DOI":"10.1161\/01.STR.20.11.1460"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Feigin V, Parag V, Lawes CM, Rodgers A, Suh I, Woodward M, et al. Smoking and elevated blood pressure are the most important risk factors for subarachnoid hemorrhage in the asia-pacific region: An overview of 26 cohorts involving 306,620 participants. Stroke, 2005; 36: 1360-1365","DOI":"10.1161\/01.STR.0000170710.95689.41"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Cui R, Iso H, Toyoshima H, Date C, Yamamoto A, Kikuchi S, et al. Serum total cholesterol levels and risk of mortality from stroke and coronary heart disease in japanese: The jacc study. Atherosclerosis, 2007; 194: 415-420","DOI":"10.1016\/j.atherosclerosis.2006.08.022"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Sundstrom J, Soderholm M, Soderberg S, Alfredsson L, Andersson M, Bellocco R, et al. Risk factors for subarachnoid haemorrhage: A nationwide cohort of 950 000 adults. Int J Epidemiol, 2019; 48: 2018-2025","DOI":"10.1093\/ije\/dyz163"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Murakami Y, Hozawa A, Okamura T, Ueshima H, Evidence for Cardiovascular Prevention From Observational Cohorts in Japan Research G. Relation of blood pressure and all-cause mortality in 180,000 japanese participants: Pooled analysis of 13 cohort studies. Hypertension, 2008; 51: 1483-1491","DOI":"10.1161\/HYPERTENSIONAHA.107.102459"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Xie L, Wu W, Chen J, Tu J, Zhou J, Qi X, et al. Cholesterol levels and hemorrhagic stroke risk in east asian versus non-east asian populations: A systematic review and meta-analysis. The neurologist, 2017; 22: 107-115","DOI":"10.1097\/NRL.0000000000000126"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Algra AM, Klijn CJ, Helmerhorst FM, Algra A, Rinkel GJ. Female risk factors for subarachnoid hemorrhage: A systematic review. Neurology, 2012; 79: 1230-1236","DOI":"10.1212\/WNL.0b013e31826aace6"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Sakata R, Shimizu Y, Soda M, Yamada M, Hsu WL, Hayashi M, et al. Effect of radiation on age at menopause among atomic bomb survivors. Radiat Res, 2011; 176: 787-795","DOI":"10.1667\/RR2676.1"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Lindbohm J, Korja M, Jousilahti P, Salomaa V, Kaprio J. Adverse lipid profile elevates risk for subarachnoid hemorrhage: A prospective population-based cohort study. Atherosclerosis, 2018; 274: 112-119","DOI":"10.1016\/j.atherosclerosis.2018.05.011"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Tirschwell DL, Smith NL, Heckbert SR, Lemaitre RN, Longstreth WT, Jr., Psaty BM. Association of cholesterol with stroke risk varies in stroke subtypes and patient subgroups. Neurology, 2004; 63: 1868-1875","DOI":"10.1212\/01.WNL.0000144282.42222.DA"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Konishi M, Iso H, Komachi Y, Iida M, Shimamoto T, Jacobs DR, Jr., et al. Associations of serum total cholesterol, different types of stroke, and stenosis distribution of cerebral arteries. The akita pathology study. Stroke, 1993; 24: 954-964","DOI":"10.1161\/01.STR.24.7.954"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Ogola BO, Zimmerman MA, Clark GL, Abshire CM, Gentry KM, Miller KS, et al. New insights into arterial stiffening: Does sex matter? Am J Physiol Heart Circ Physiol, 2018; 315: H1073-H1087","DOI":"10.1152\/ajpheart.00132.2018"}],"container-title":["Journal of Atherosclerosis and Thrombosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jat\/32\/11\/32_65650\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T04:17:27Z","timestamp":1761970647000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jat\/32\/11\/32_65650\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,1]]},"references-count":20,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.5551\/jat.65650","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.10.15.24315569","asserted-by":"object"}]},"ISSN":["1340-3478","1880-3873"],"issn-type":[{"value":"1340-3478","type":"print"},{"value":"1880-3873","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,1]]},"article-number":"65650"}}