{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T12:14:54Z","timestamp":1742645694868},"reference-count":0,"publisher":"Ayub Medical College, Abbottabad Pakistan","issue":"2","license":[{"start":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T00:00:00Z","timestamp":1684195200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Ayub Med Coll Abbottabad"],"abstract":"<jats:p>Background: Splenic abscess is an uncommon\u00a0condition, with autopsy studies estimating an incidence rate of 0.14\u20130.70%. Causative organisms can be extremely diverse. Burkholderia pseudomallei is the most common cause of splenic abscess in melioidosis-endemic areas. Methods: We reviewed 39 cases of splenic abscesses in a district hospital in Kapit, Sarawak, from January 2017 to December 2018. The demographics, clinical characteristics, underlying diseases, causative organisms, therapeutic methods, and mortality rates were investigated. Results: There were 21 males and 18 females (mean age, 33.7\u00b12.7 years). Almost all patients (97.4%) had a history of pyrexia. Diabetes mellitus was present in 8 patients (20.5%). Splenic abscesses were diagnosed using ultrasonography and were multiple in all 39 cases. Positive blood cultures were obtained in 20 patients (51.3%), and all yielded B. pseudomallei. Melioidosis serology was positive in 9 of 19 patients (47.4%) with negative blood cultures. All patients were treated for melioidosis with antibiotics without the need for surgical intervention. All splenic abscesses resolved after anti-melioidosis treatment was completed. One patient died (2.6%) as a result of B. pseudomallei septicaemia with multiorgan failure. Conclusion: Ultrasonography is a valuable tool for diagnosing splenic abscesses in resource-limited settings. B. pseudomallei was the most common etiological agent of splenic abscesses in our study.\nBackground: Splenic abscess is an uncommon\u00a0condition, with autopsy studies estimating an incidence rate of 0.14\u20130.70%. Causative organisms can be extremely diverse. Burkholderia pseudomallei is the most common cause of splenic abscess in melioidosis-endemic areas. Methods: We reviewed 39 cases of splenic abscesses in a district hospital in Kapit, Sarawak, from January 2017 to December 2018. The demographics, clinical characteristics, underlying diseases, causative organisms, therapeutic methods, and mortality rates were investigated. Results: There were 21 males and 18 females (mean age, 33.7\u00b12.7 years). Almost all patients (97.4%) had a history of pyrexia. Diabetes mellitus was present in 8 patients (20.5%). Splenic abscesses were diagnosed using ultrasonography and were multiple in all 39 cases. Positive blood cultures were obtained in 20 patients (51.3%), and all yielded B. pseudomallei. Melioidosis serology was positive in 9 of 19 patients (47.4%) with negative blood cultures. All patients were treated for melioidosis with antibiotics without the need for surgical intervention. All splenic abscesses resolved after anti-melioidosis treatment was completed. One patient died (2.6%) as a result of B. pseudomallei septicaemia with multiorgan failure. Conclusion: Ultrasonography is a valuable tool for diagnosing splenic abscesses in resource-limited settings. B. pseudomallei was the most common etiological agent of splenic abscesses in our study.<\/jats:p>","DOI":"10.55519\/jamc-02-11390","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T05:32:45Z","timestamp":1684819965000},"source":"Crossref","is-referenced-by-count":4,"title":["BURKHOLDERIA PSEUDOMALLEI AS THE PREDOMINANT CAUSE OF SPLENIC ABSCESS IN KAPIT, SARAWAK, MALAYSIAN BORNEO"],"prefix":"10.55519","volume":"35","author":[{"given":"Chee Yik","family":"Chang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"34325","published-online":{"date-parts":[[2023,5,16]]},"container-title":["Journal of Ayub Medical College Abbottabad"],"original-title":[],"deposited":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T05:32:45Z","timestamp":1684819965000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamc.ayubmed.edu.pk\/jamc\/index.php\/jamc\/article\/view\/11390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,16]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,4,16]]}},"URL":"https:\/\/doi.org\/10.55519\/jamc-02-11390","relation":{},"ISSN":["1819-2718","1025-9589"],"issn-type":[{"value":"1819-2718","type":"electronic"},{"value":"1025-9589","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5,16]]}}}