{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T18:42:30Z","timestamp":1659206550237},"reference-count":0,"publisher":"Ayub Medical College, Abbottabad Pakistan","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Ayub Med Coll Abbottabad"],"abstract":"<jats:p>Background: We hypothesize that a change in lung ultrasound score (LUS) can assist in the early diagnosis of weaning-induced respiratory failure (RF). The objective of this study was to determine the utility of LUS in weaning patients with mitral regurgitation (MR) from mechanical ventilation (MV). Methods: This prospective observational study included patients with acute coronary syndrome (ACS) who required invasive MV after angiography\/angioplasty. Echocardiography was performed and MR was recorded. When the patient was considered ready for extubation, a spontaneous breathing trial (SBT) was performed and pre- and post-SBT LUS was calculated. Patients who successfully passed the SBT were extubated and followed up for 48 hours for the signs of RF and outcomes. Results: We enrolled 215 patients, out of which MR occurred in 51(23.7%) patients. On post-SBT lung ultrasound, patients with MR were more likely to have B2 lines compared to those without MR; 15.7% vs. 3.7%; p=0.002 and mean LUS was significantly higher for patients with MR as compared to patients without MR; 2.75\u00b13.21 vs. 1.37\u00b1 2.02; p&lt;0.001. Post-extubation RF and mean CCU stay were significantly higher in MR patients, 49.0% (25) vs. 32.3% (53); p=0.030 and 3.53\u00b11.54 days vs. 2.41\u00b11.1 days; p&lt;0.001 respectively. However, re-intubation and coronary care unit (CCU) mortality rate were not significantly different between patients with and without MR; 7.8% (4\/51) vs. 3.7% (6\/164); p=0.215, and 5.9% (3\/51) vs. 3% (5\/164); p=0.35 respectively. Conclusions: Bedside LU is a convenient tool to detect changes in cardiopulmonary interactions during weaning for patients with MR post-ACS.<\/jats:p>","DOI":"10.55519\/jamc-03-10145","type":"journal-article","created":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T18:19:48Z","timestamp":1659205188000},"page":"422-426","source":"Crossref","is-referenced-by-count":0,"title":["ROLE OF LUNG ULTRASOUND DURING WEANING IN PATIENT WITH MITRAL REGURGITATION POST ANGIOPLASTY"],"prefix":"10.55519","volume":"34","author":[{"given":"Mujtaba","family":"Hassan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Imran","family":"Ansari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jawed","family":"Abubaker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madiha","family":"Umair","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Komal","family":"Baloch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Musa","family":"Karim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nawal","family":"Salahuddin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"34325","published-online":{"date-parts":[[2022,6,21]]},"container-title":["Journal of Ayub Medical College Abbottabad"],"original-title":[],"link":[{"URL":"https:\/\/jamc.ayubmed.edu.pk\/jamc\/index.php\/jamc\/article\/download\/10145\/3317","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jamc.ayubmed.edu.pk\/jamc\/index.php\/jamc\/article\/download\/10145\/3317","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T18:19:48Z","timestamp":1659205188000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamc.ayubmed.edu.pk\/jamc\/index.php\/jamc\/article\/view\/10145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,21]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,6,21]]}},"URL":"https:\/\/doi.org\/10.55519\/jamc-03-10145","relation":{},"ISSN":["1819-2718","1025-9589"],"issn-type":[{"value":"1819-2718","type":"electronic"},{"value":"1025-9589","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6,21]]}}}