{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T13:37:36Z","timestamp":1747229856129,"version":"3.40.5"},"reference-count":0,"publisher":"Ayub Medical College, Abbottabad Pakistan","issue":"3","license":[{"start":{"date-parts":[[2023,7,9]],"date-time":"2023-07-09T00:00:00Z","timestamp":1688860800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Ayub Med Coll Abbottabad"],"abstract":"<jats:p>Background: Worldwide, cardiovascular diseases are the major cause of mortality and morbidity with acute coronary syndrome as the most common clinical manifestation. In a typical clinical setup, around 30% of the patients presented with \u201cST-segment elevation myocardial infarction (STEMI)\u201d caused by the complete occlusion of the coronary artery and the remaining 70% with intermittent or partial occlusion of the coronary termed as non-ST elevation The aim of this study was to assess the prevalence and characteristics of non-obstructive coronary arteries among patients presenting with non ST-elevation acute coronary syndrome (NSTE-ACS) at a tertiary care cardiac center of Karachi, Pakistan. Methods: This was a descriptive cross-sectional study, conducted at a tertiary care hospital in Karachi. Study inclusion criteria were patients of either gender admitted with NSTE-ACS and age between 30-70 years. A routine coronary angiogram was performed in all the patients and the absence of \u226550% stenosis in any major epicardial vessel was taken in non-obstructive coronaries. Results: A total of 174 patients (30\u201370 years) were included, of which 99 (56.9%) were male and the mean age was 59.43\u00b111.24 years. In the distribution of socioeconomic status, 54 (31.0%) were lower class, middle class 81 (46.6%) while upper-class status were 39 (22.4%). Hypertension was observed in 76 (43.7%), chronic kidney disease in 20 (11.5%), and hyperlipidemia in 55 (31.6%). Non-obstructive coronary arteries were noted in 25 (14.4%) patients. Conclusion: It is to be concluded that non-obstructive coronary arteries are fairly prevalent in patients arriving in hospital with NSTE-ACS in our population. Further research is needed to better understand the underlying pathophysiology and optimal management strategies for patients with NOCA in the setting of NSTEMI.<\/jats:p>","DOI":"10.55519\/jamc-03-12028","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T04:56:30Z","timestamp":1693976190000},"source":"Crossref","is-referenced-by-count":0,"title":["NON-OBSTRUCTIVE CORONARIES IN PATIENTS PRESENTING WITH THE NON ST-ELEVATION ACUTE CORONARY SYNDROME"],"prefix":"10.55519","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3047-3142","authenticated-orcid":false,"given":"Shakir","family":"Zada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid Iqbal","family":"Bhatti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8225-8666","authenticated-orcid":false,"given":"Muhammad","family":"Zeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romana","family":"Pirah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniyal","family":"Musaddiq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7526-0417","authenticated-orcid":false,"given":"Aziz ur Rehman","family":"Memon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"34325","published-online":{"date-parts":[[2023,7,9]]},"container-title":["Journal of Ayub Medical College Abbottabad"],"original-title":[],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T04:56:30Z","timestamp":1693976190000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamc.ayubmed.edu.pk\/jamc\/index.php\/jamc\/article\/view\/12028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,9]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,7,9]]}},"URL":"https:\/\/doi.org\/10.55519\/jamc-03-12028","relation":{},"ISSN":["1819-2718","1025-9589"],"issn-type":[{"type":"electronic","value":"1819-2718"},{"type":"print","value":"1025-9589"}],"subject":[],"published":{"date-parts":[[2023,7,9]]}}}