{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T08:10:25Z","timestamp":1733731825838,"version":"3.30.1"},"reference-count":0,"publisher":"Ayub Medical College, Abbottabad Pakistan","issue":"3","license":[{"start":{"date-parts":[[2024,9,8]],"date-time":"2024-09-08T00:00:00Z","timestamp":1725753600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Ayub Med Coll Abbottabad"],"abstract":"<jats:p>Background: Regadenoson is highly selective A2A adenosine receptors agonist used for stress myocardial perfusion scintigraphy. This study presents our initial experience utilizing Regadenoson as a myocardial perfusion stress agent, aimed to assess the safety of Regadenoson for stress myocardial perfusion scintigraphy. Methods: Following Institutional Ethical Review Borad approval, adult patients presenting for myocardial stress perfusion scintigraphy were included using non-probability consecutive sampling. Exclusions included second or third-degree AV block, unstable angina, recent myocardial infarction, severe hypotension, or significant heart failure. Demographic data, co-morbidities, vitals, and adverse events were recorded. Results: Sixty-three patients were included, predominantly male (63.5%), with a mean age of 56.81\u00b112.95 years. Hyperlipidaemia was the most common co-morbidity (47.6%). Systolic and diastolic blood pressure decreased acutely but normalised by 60 minutes. No serious adverse effects occurred, though transient ST segment depression was noted in 8.3% of patients. The most common adverse effects were dyspnoea (23.8%) and headache (21.4%). Conclusion: Regadenoson is associated with transient haemodynamic changes and non-serious transient adverse effects.<\/jats:p>","DOI":"10.55519\/jamc-03-13734","type":"journal-article","created":{"date-parts":[[2024,11,30]],"date-time":"2024-11-30T10:40:38Z","timestamp":1732963238000},"page":"630-635","source":"Crossref","is-referenced-by-count":0,"title":["REGADENOSON MYOCARDIAL PERFUSION SCINTIGRAPHY: A SINGLE CENTRE EXPERIENCE"],"prefix":"10.55519","volume":"36","author":[{"given":"Muhammad","family":"Adil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Zaigham Salim Dar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Shahbaz Afsar Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Fida Hussain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Asad Malik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Husnain Saleem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"34325","published-online":{"date-parts":[[2024,9,8]]},"container-title":["Journal of Ayub Medical College Abbottabad"],"original-title":[],"link":[{"URL":"https:\/\/www.jamc.ayubmed.edu.pk\/jamc\/index.php\/jamc\/article\/download\/13734\/3803","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.jamc.ayubmed.edu.pk\/jamc\/index.php\/jamc\/article\/download\/13734\/3803","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T07:38:48Z","timestamp":1733729928000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jamc.ayubmed.edu.pk\/jamc\/index.php\/jamc\/article\/view\/13734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,8]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,9,8]]}},"URL":"https:\/\/doi.org\/10.55519\/jamc-03-13734","relation":{},"ISSN":["1819-2718","1025-9589"],"issn-type":[{"type":"electronic","value":"1819-2718"},{"type":"print","value":"1025-9589"}],"subject":[],"published":{"date-parts":[[2024,9,8]]}}}