{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T17:47:43Z","timestamp":1779385663464,"version":"3.53.1"},"reference-count":0,"publisher":"Ayub Medical College, Abbottabad Pakistan","issue":"4","license":[{"start":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T00:00:00Z","timestamp":1703203200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Ayub Med Coll Abbottabad"],"abstract":"<jats:p>Background: The contrast-induced nephropathy (CIN) is a common complication of primary percutaneous coronary intervention (PCI) it has been reported to be associated with an increased risk of mortality.\u00a0 The study reported the in-hospital mortality among patients who developed CIN after primary PCI. Methods: This descriptive cross-sectional study was conducted on a sample of consecutive who developed CIN after primary PCI at a tertiary care cardiac hospital in Karachi, Pakistan. The CIN was defined as either a relative increase of 25% or an absolute increase of 0.5 mg\/dL in post-procedure serum creatinine within 72 hours. The in-hospital mortality status was recorded and clinical and demographic predictors of in-hospital mortality were identified with the help of binary logistic regression analysis. Results: \u00a0In the study sample of 402 patients, 74.1% (298) were male and the mean age of the study sample was 59.4\u00b111.5 years. The in-hospital mortality rate was 9.7% (39). On multivariable analysis, an increased risk of mortality was found to be independently associated with inferior wall myocardial infarction (IWMI) with right ventricular (RV) infarction, intra-procedure arrhythmias, and pump failure with an adjusted odds ratio of 3.63 [95% CI: 1.31-10.08; p=0.013], 5.53 [95% CI: 1.39-22.06; p=0.015], and 8.94 [95% CI: 3.99-20.02; p&lt;0.001], respectively. Conclusion: In conclusion, there is a high rate of mortality for patients who develop CIN after primary PCI, and the risk of mortality is further aggravated by the presence of IWMI with RV infarction, intra-procedure arrhythmias, and pump failure.<\/jats:p>","DOI":"10.55519\/jamc-04-12124","type":"journal-article","created":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T09:31:55Z","timestamp":1727861515000},"source":"Crossref","is-referenced-by-count":2,"title":["ASSESSING IN-HOSPITAL MORTALITY AND PREDICTORS IN PATIENTS WITH CONTRAST-INDUCED NEPHROPATHY FOLLOWING PRIMARY PERCUTANEOUS CORONARY INTERVENTION"],"prefix":"10.55519","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6580-7193","authenticated-orcid":false,"given":"Rajesh","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kheraj","family":"Mal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abiha","family":"Urooj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barkha","family":"Lohana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6227-7611","authenticated-orcid":false,"given":"Mohammad","family":"Rasool","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Yousuf","family":"Daud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kubbra","family":"Rahooja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Samad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uroosa","family":"Safdar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Bin","family":"Naseer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalsoom","family":"Chachar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Ishaq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahid Ur","family":"Rehman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musa","family":"Karim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"34325","published-online":{"date-parts":[[2023,12,22]]},"container-title":["Journal of Ayub Medical College Abbottabad"],"original-title":[],"deposited":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T09:31:55Z","timestamp":1727861515000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamc.ayubmed.edu.pk\/jamc\/index.php\/jamc\/article\/view\/12124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,22]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,10,10]]}},"URL":"https:\/\/doi.org\/10.55519\/jamc-04-12124","relation":{},"ISSN":["1819-2718","1025-9589"],"issn-type":[{"value":"1819-2718","type":"electronic"},{"value":"1025-9589","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12,22]]}}}