{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T23:44:50Z","timestamp":1784591090356,"version":"3.55.0"},"reference-count":0,"publisher":"Ayub Medical College, Abbottabad Pakistan","issue":"4","license":[{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Ayub Med Coll Abbottabad"],"abstract":"<jats:p>Background: Acne vulgaris is a common skin condition, involving upto 90% of the teenage population, being more common in women than in men. Post acne scars are the sequelae, leading to low esteem and self confidence in the affected individuals. Methods: Thirty patients participated in the study. On each patient, over the left side of the face, microneedling was done using topical insulin as a medium, while on the right side of the face, simple microneedling was done. Four such sessions, a month apart, were done in all the patients. They were called for follow up and the response was based on the \"Acne scar assessment scale\", in which Grade-0 referred to no improvement, Grade-1 referred to an improvement of less than 25%, Grade-2 was an improvement between 25\u201350%, Grade-3 meant an improvement between 50\u201375%, and, Grade-4 referred to an improvement of greater than 75%. Results: After completion of the sessions, over the left side of the face, where microneedling was done with insulin 11 (36.7%) patients showed Grade-2 improvement, while 19 (63.3%) patients showed Grade-3 improvement. On the right side of the face where simple microneedling was done, 10 (33.3%) patients showed an improvement of Grade-0, and 20 (66.6%) patients showed an improvement of Grade-1. Conclusion: After this study, we conclude that microneedling combined with topical insulin, shows better results in patients with scarring. It can be a breakthrough in the treatment of post acne scars, due to easier availability and lesser cost of insulin.<\/jats:p>","DOI":"10.55519\/jamc-04-12893","type":"journal-article","created":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T08:19:13Z","timestamp":1737274753000},"source":"Crossref","is-referenced-by-count":2,"title":["SIMPLE MICRONEEDLING VERSUS MICRONEEDLING WITH TOPICAL INSULIN IN THE TREATMENT OF POST ACNE ATROPHIC SCARS; A SPLIT FACE COMPARATIVE STUDY"],"prefix":"10.55519","volume":"36","author":[{"family":"Mira Ali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Najia Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Seemab Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Afshan kiran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"34325","published-online":{"date-parts":[[2024,11,25]]},"container-title":["Journal of Ayub Medical College Abbottabad"],"original-title":[],"deposited":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T08:19:29Z","timestamp":1737447569000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ayubmed.edu.pk\/jamc\/index.php\/jamc\/article\/view\/12893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,25]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,11,25]]}},"URL":"https:\/\/doi.org\/10.55519\/jamc-04-12893","relation":{},"ISSN":["1819-2718","1025-9589"],"issn-type":[{"value":"1819-2718","type":"electronic"},{"value":"1025-9589","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11,25]]}}}