{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T11:42:58Z","timestamp":1713267778308},"reference-count":0,"publisher":"SEMES (Sociedad Espanola de Medicina de Urgencias y Emergencias)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Emergencias"],"abstract":"<jats:p>Objetivo. Investigar el efecto de un protocolo de reposici\u00f3n restrictiva de calcio frente a una estrategia liberal en pacientes con shock s\u00e9ptico. M\u00e9todos. Estudio multic\u00e9ntrico, antes-despu\u00e9s y retrospectivo que evalu\u00f3 el efecto de la implementaci\u00f3n de un protocolo de reposici\u00f3n restrictiva de calcio en pacientes con shock s\u00e9ptico. Los pacientes que ingresaron en unidades de cuidados intensivos (UCI) entre mayo de 2019 y abril de 2021 se asignaron al grupo con administraci\u00f3n liberal, y los que se presentaron entre mayo de 2021 y abril de 2022 \u2013tras la implementaci\u00f3n del protocolo\u2013 al grupo con administraci\u00f3n restrictiva. La variable de resultado principal fue la mortalidad a 28 d\u00edas. Se realiz\u00f3 un emparejamiento por puntuaci\u00f3n de propensi\u00f3n. Resultados. Se incluyeron 644 pacientes, 453 en el grupo liberal y 191 en el grupo restrictivo. De los que 553 se emparejaron (386 en el grupo liberal, y 167 en el grupo restrictivo). No hubo diferencias entre los dos grupos en la mortalidad a los 28 d\u00edas (35,3% vs 32,3%; HR: 0,97; IC 95%: 0,72-1,29), en la finalizaci\u00f3n del shock (81,5% vs a 83,8%; HR: 0,89; IC 95%: 0,73-1,09) ni en la puntuaci\u00f3n de la escala SOFA (2,1 vs 2,6; p = 0,20). Conclusiones. La implementaci\u00f3n de un protocolo de administraci\u00f3n restrictiva de calcio, en pacientes con shock s\u00e9ptico, no se asoci\u00f3 a una disminuci\u00f3n de la mortalidad a los 28 d\u00edas en comparaci\u00f3n con una administraci\u00f3n liberal. No obstante, la reposici\u00f3n de calcio podr\u00eda reducirse sin efectos adversos.<\/jats:p>","DOI":"10.55633\/s3me\/021.2024","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T11:21:53Z","timestamp":1713266513000},"source":"Crossref","is-referenced-by-count":0,"title":["Restrictive calcium replacement in septic shock: a multicenter before-after intervention study"],"prefix":"10.55633","author":[{"given":"Ryoung","family":"Eun Ko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daun","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumin","family":"Baek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi Ryang","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gee Young","family":"Suh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joonghyun","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinseo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Yeon","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gun Tak","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Eun","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae Gun","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You Hwan","family":"jO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"33356","published-online":{"date-parts":[[2024,4,16]]},"container-title":["Emergencias"],"original-title":["Reposici\u00f3n restrictiva de calcio en pacientes con shock s\u00e9ptico: estudio de intervenci\u00f3n antes-despu\u00e9s"],"deposited":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T11:21:58Z","timestamp":1713266518000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistaemergencias.org\/articulo\/reposicion-restrictiva-de-calcio-en-pacientes-con-shock-septico-estudio-de-intervencion-antes-despues\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,16]]},"references-count":0,"URL":"https:\/\/doi.org\/10.55633\/s3me\/021.2024","relation":{},"ISSN":["1137-6821","2386-5857"],"issn-type":[{"value":"1137-6821","type":"print"},{"value":"2386-5857","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,16]]}}}