{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T18:24:54Z","timestamp":1757615094990,"version":"3.44.0"},"reference-count":0,"publisher":"SEMES (Sociedad Espanola de Medicina de Urgencias y Emergencias)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Emergencias"],"published-print":{"date-parts":[[2025,9,5]]},"abstract":"<jats:p>Objetivos. Evaluar el impacto de la profilaxis del VRS con nirsevimab durante su segundo a\u00f1o de administraci\u00f3n y\nanalizar las diferencias entre las diferentes estrategias desplegadas por las comunidades aut\u00f3nomas (CCAA) durante\nesta temporada epid\u00e9mica.\nM\u00e9todos. Estudio anal\u00edtico retrospectivo en 15 servicios de urgencias pedi\u00e1tricos de 9 CCAA. Se incluyeron todos los\nlactantes menores de 6 meses atendidos en los meses de noviembre, diciembre y enero durante 5 temporadas epid\u00e9micas (2018-2019, 2019-2020, 2022-2023, 2023-2024 y 2024-2025).\nResultados. En comparaci\u00f3n con el promedio de las temporadas epid\u00e9micas previas a la introducci\u00f3n del nirsevimab,\nen 2024-2025 hubo una disminuci\u00f3n de los episodios de bronquiolitis aguda del 65,5% (IC 95%: 64,3-63,7;\nP &lt; 0,001). Los ingresos por bronquiolitis disminuyeron un 74,7% (IC 95%: 72,7-76,6; P &lt; 0,001) y los ingresos en las\nunidades de cuidados intensivos pedi\u00e1tricos UCIP se redujeron en un 72,9% (IC 95%: 68,1-77,2; P &lt; 0,001). Las reducciones conseguidas en la temporada 2024-2025 fueron mayores a las obtenidas en la temporada 2023-2024. El\nhospital perteneciente a la CCAA que decidi\u00f3 no inmunizar a los lactantes nacidos antes del inicio de la epidemia obtuvo los peores resultados. En las CCAA que aplicaron la misma estrategia, obtuvo peores resultados aquella que inmuniz\u00f3 a los nacidos fuera de temporada a trav\u00e9s de hospitales seleccionados en lugar de en los centros de atenci\u00f3n\nprimaria.\nConclusiones. La profilaxis con nirsevimab en Espa\u00f1a durante la temporada 2024-2025 ha conseguido proteger a los lactantes menores de 6 meses de la infecci\u00f3n por VRS con una efectividad a\u00fan mayor. Sin embargo, existen diferencias entre CCAA en probable relaci\u00f3n con la estrategia de inmunizaci\u00f3n implementada.<\/jats:p>","DOI":"10.55633\/s3me\/081.2025","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T12:37:48Z","timestamp":1757075868000},"source":"Crossref","is-referenced-by-count":0,"title":["Unequal impact of respiratory syncytial virus immunization in Spanish pediatric emergency departments"],"prefix":"10.55633","author":[{"given":"David","family":"Andina Mart\u00ednez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Barrueco Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Escalada Pellitero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adri\u00e1n","family":"Ranera M\u00e1laga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Lorenzo","family":"Guerra D\u00edez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ver\u00f3nica","family":"Gimeno-Hern\u00e1ndez Garza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nerea","family":"Gonz\u00e1lez Arza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Ventura Pernia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"S\u00e1nchez Tatay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Ferrero Garc\u00eda-Loygorri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bego\u00f1a","family":"de Miguel Lavisier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Ba\u00f1os L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amaia","family":"C\u00e1mara Otegui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Gij\u00f3n Mediavilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gemma","family":"Claret Teruel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Antonio","family":"Alonso-Cadenas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"33356","published-online":{"date-parts":[[2025,9,5]]},"container-title":["Emergencias"],"original-title":["Impacto desigual de la inmunizaci\u00f3n frente al virus respiratorio sincitial en los servicios de urgencias pedi\u00e1tricos espa\u00f1oles"],"deposited":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T12:37:48Z","timestamp":1757075868000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistaemergencias.org\/articulo\/impacto-desigual-de-la-inmunizacion-frente-al-virus-respiratorio-sincitial-en-los-servicios-de-urgencias-pediatricos-espanoles\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,5]]},"references-count":0,"URL":"https:\/\/doi.org\/10.55633\/s3me\/081.2025","relation":{},"ISSN":["1137-6821","2386-5857"],"issn-type":[{"type":"print","value":"1137-6821"},{"type":"electronic","value":"2386-5857"}],"subject":[],"published":{"date-parts":[[2025,9,5]]}}}