{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T00:25:25Z","timestamp":1719966325924},"reference-count":0,"publisher":"SEMES (Sociedad Espanola de Medicina de Urgencias y Emergencias)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Emergencias"],"abstract":"<jats:p>La p\u00farpura tromb\u00f3tica trombocitop\u00e9nica adquirida o inmune (PTTi) es una microangiopat\u00eda tromb\u00f3tica (MAT) con una elevada mortalidad si no se instaura un tratamiento precoz. El inicio habitualmente brusco de la enfermedad hace que, en la mayor\u00eda de los pacientes, el diagn\u00f3stico inicial se haga en los servicios de urgencias hospitalarios (SUH), donde se debe sospechar esta entidad con la mayor inmediatez posible. Esta gu\u00eda, elaborada por profesionales de Medicina de Urgencias y de Hematolog\u00eda, establece unas recomendaciones en cuanto al diagn\u00f3stico, derivaci\u00f3n y tratamiento de los pacientes con sospecha de PTTi en los SUH. Se debe sospechar PTTi en todo paciente que presente una anemia hemol\u00edtica microangiop\u00e1tica, prueba de Coombs directo negativa y trombocitopenia pudiendo asociar, adem\u00e1s, fiebre, alteraciones neurol\u00f3gicas y cardiacas. Si tras la aplicaci\u00f3n de alguno de los algoritmos diagn\u00f3sticos existentes, hay una alta probabilidad de que el paciente presente una PTTi, deber\u00eda iniciarse tratamiento con recambio plasm\u00e1tico, inmunosupresores y valorar el inicio de caplacizumab. Adem\u00e1s, debe gestionarse el traslado inmediato de los pacientes al Servicio de Hematolog\u00eda, bien del mismo centro o a uno de referencia.<\/jats:p>","DOI":"10.55633\/s3me\/e099.2023","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T13:05:47Z","timestamp":1719925547000},"source":"Crossref","is-referenced-by-count":0,"title":["Immune thrombotic thrombocytopenic purpura: clinical suspicion and basic management in emergency departments \u2014 an expert review and consensus statement from the Spanish societies of hematology and hemotherapy (SEHH) and emergency medicine (SEMES)"],"prefix":"10.55633","author":[{"given":"Cristina","family":"Pascual-Izquierdo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascual","family":"Pi\u00f1era Salmer\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Temboury Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Valc\u00e1rcel Ferreiras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Jim\u00e9nez Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ram\u00f3n","family":"Salinas Argente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"del Arco Gal\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"de la Rubia Comos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"33356","published-online":{"date-parts":[[2024,7,2]]},"container-title":["Emergencias"],"original-title":["P\u00farpura trombocitop\u00e9nica tromb\u00f3tica inmune: sospecha y manejo b\u00e1sico en los servicios de urgencias. Revisi\u00f3n y consenso de un grupo de expertos de las sociedades cient\u00edficas SEHH y SEMES"],"deposited":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T13:05:53Z","timestamp":1719925553000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistaemergencias.org\/numeros-anteriores\/volumen-35\/numero-1\/purpura-trombocitopenica-trombotica-inmune-sospecha-y-manejo-basico-en-los-servicios-de-urgencias-revision-y-consenso-de-un-grupo-de-expertos-de-las-sociedades-cientificas-sehh-y-semes\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,2]]},"references-count":0,"URL":"https:\/\/doi.org\/10.55633\/s3me\/e099.2023","relation":{},"ISSN":["1137-6821","2386-5857"],"issn-type":[{"value":"1137-6821","type":"print"},{"value":"2386-5857","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,2]]}}}