{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T10:13:18Z","timestamp":1788603198880,"version":"build-2803163510"},"reference-count":0,"publisher":"Greater Baltimore Medical Center","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Community Hospital Internal Medicine Perspectives"],"abstract":"<jats:p>Primary CNS lymphoma (PCNSL) accounts for up to 15% of non-Hodgkin lymphomas in HIV patients and is the second most common cause of space-occupying brain lesions in HIV patients after CNS toxoplasmosis. Differentiation of PCNL and CNS toxoplasmosis is crucial as PCNL carries a poor prognosis with survival time of 2-4 months without treatment but can be improved with prompt initiation of chemotherapy. These two entities often present clinically in a similar manner, and conventional imaging can also be a diagnostic challenge due to overlapping imaging characteristics. Thus, definitive diagnosis of PCNSL relies on histopathologic confirmation. Here, we present a case of intracranial lesion that presented acutely in the context of headache and left sided body weakness and was found to have PCNSL<\/jats:p>","DOI":"10.55729\/2000-9666.1251","type":"journal-article","created":{"date-parts":[[2023,11,5]],"date-time":"2023-11-05T03:14:05Z","timestamp":1699154045000},"source":"Crossref","is-referenced-by-count":0,"title":["Acute presentation of primary CNS lymphoma mimicking Toxoplasma in HIV infection"],"prefix":"10.55729","volume":"13","author":[{"given":"Indira","family":"Acharya","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, MedStar Union Memorial Hospital, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott R.","family":"DeBoer","sequence":"additional","affiliation":[{"name":"MedStar Health, MedStar Franklin Square Medical Center, Baltimore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepty","family":"Bhansali","sequence":"additional","affiliation":[{"name":"MedStar Health, MedStar Franklin Square Medical Center, Baltimore,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"34701","published-online":{"date-parts":[[2023,11,4]]},"container-title":["Journal of Community Hospital Internal Medicine Perspectives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/scholarlycommons.gbmc.org\/cgi\/viewcontent.cgi?article=1251&amp;context=jchimp","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T10:00:44Z","timestamp":1788602444000},"score":1,"resource":{"primary":{"URL":"https:\/\/scholarlycommons.gbmc.org\/jchimp\/vol13\/iss6\/5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,4]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,11,4]]}},"URL":"https:\/\/doi.org\/10.55729\/2000-9666.1251","relation":{},"ISSN":["2000-9666"],"issn-type":[{"value":"2000-9666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,4]]}}}