{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T10:13:13Z","timestamp":1788603193365,"version":"build-2803163510"},"reference-count":0,"publisher":"Greater Baltimore Medical Center","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Community Hospital Internal Medicine Perspectives"],"abstract":"<jats:p>Drug-induced urine discoloration, although usually benign, can still raise concern in healthcare facilities. This case report presents the second case of purple urine discoloration associated with cefiderocol in a 64-year-old male admitted to the intensive care unit for ventilator-associated pneumonia. The patient required broad-spectrum antibiotic treatment with vancomycin, cefiderocol, amikacin, and micafungin. On the fourth day after initiating antibiotics, the presence of purplish urine in the foley bag was noted. Urinalysis showed 11-25 red blood cells\/hpf, but cultures ruled out urinary tract infection. Further laboratory workup did not reveal any evidence of hemolysis or rhabdomyolysis. Cultures from the endotracheal aspirate grew multidrug-resistant Pseudomonas. Cefiderocol and amikacin were continued to complete a seven-day course. Two days after completion of the cefiderocol course, the urine discoloration cleared up, providing strong evidence that cefiderocol was the cause of the discoloration.<\/jats:p>","DOI":"10.55729\/2000-9666.1256","type":"journal-article","created":{"date-parts":[[2023,11,5]],"date-time":"2023-11-05T03:13:41Z","timestamp":1699154021000},"source":"Crossref","is-referenced-by-count":2,"title":["Purplish Discoloration of Urine in a Patient Receiving Cefiderocol: A Rare Adverse Effect"],"prefix":"10.55729","volume":"13","author":[{"given":"Mohammed Rifat","family":"Shaik","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Maryland Medical Center Midtown Campus, Baltimore, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishat Anjum","family":"Shaik","sequence":"additional","affiliation":[{"name":"Department of Medicine, Guntur Medical College, Guntur, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Hossain","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Maryland Medical Center Midtown Campus, Baltimore, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvina","family":"Yunasan","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Maryland Medical Center Midtown Campus, Baltimore, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksan","family":"Khachatryan","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Maryland Medical Center Midtown Campus, Baltimore, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Chow","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"34701","published-online":{"date-parts":[[2023,11,4]]},"container-title":["Journal of Community Hospital Internal Medicine Perspectives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/scholarlycommons.gbmc.org\/cgi\/viewcontent.cgi?article=1256&amp;context=jchimp","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T10:00:34Z","timestamp":1788602434000},"score":1,"resource":{"primary":{"URL":"https:\/\/scholarlycommons.gbmc.org\/jchimp\/vol13\/iss6\/10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,4]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,11,4]]}},"URL":"https:\/\/doi.org\/10.55729\/2000-9666.1256","relation":{},"ISSN":["2000-9666"],"issn-type":[{"value":"2000-9666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,4]]}}}