{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T10:13:11Z","timestamp":1788603191977,"version":"build-2803163510"},"reference-count":0,"publisher":"Greater Baltimore Medical Center","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Community Hospital Internal Medicine Perspectives"],"abstract":"<jats:p>As the use of immune checkpoint inhibitors (ICPi) such as pembrolizumab is rapidly expanding in the field of immuno-oncology, it is crucial for healthcare providers to be aware of their immune-related adverse effects (irAE) which are thought to be driven by augmented immune response of T-cells. While neurologic immune-related adverse events (irAE) are underrepresented in literature, their consequences could lead to fatal outcomes. In this report, we describe the case of a patient with excellent performance status prior to pembrolizumab therapy who subsequently suffered myasthenic crisis eventually requiring tracheostomy and long-term mechanical ventilation.<\/jats:p>","DOI":"10.55729\/2000-9666.1352","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T22:01:26Z","timestamp":1715292086000},"source":"Crossref","is-referenced-by-count":0,"title":["Pembrolizumab-induced Myasthenia Gravis and Myocarditis"],"prefix":"10.55729","volume":"14","author":[{"given":"Jisun","family":"Won","sequence":"first","affiliation":[{"name":"Abington Memorial Hospital, Department of Internal Medicine, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Zhao","sequence":"additional","affiliation":[{"name":"Abington Memorial Hospital, Department of Internal Medicine, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"States","sequence":"additional","affiliation":[{"name":"Abington Memorial Hospital, Department of Internal Medicine, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Brown","sequence":"additional","affiliation":[{"name":"Abington Memorial Hospital, Department of Internal Medicine, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdallah","family":"El-habr","sequence":"additional","affiliation":[{"name":"Abington Memorial Hospital, Department of Internal Medicine, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Damsker","sequence":"additional","affiliation":[{"name":"Abington Memorial Hospital, Department of Internal Medicine, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"34701","published-online":{"date-parts":[[2024,5,7]]},"container-title":["Journal of Community Hospital Internal Medicine Perspectives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/scholarlycommons.gbmc.org\/cgi\/viewcontent.cgi?article=1352&amp;context=jchimp","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T09:58:37Z","timestamp":1788602317000},"score":1,"resource":{"primary":{"URL":"https:\/\/scholarlycommons.gbmc.org\/jchimp\/vol14\/iss3\/17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,7]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,5,7]]}},"URL":"https:\/\/doi.org\/10.55729\/2000-9666.1352","relation":{},"ISSN":["2000-9666"],"issn-type":[{"value":"2000-9666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,7]]}}}