{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:12:19Z","timestamp":1791223939577,"version":"4.1.0"},"reference-count":0,"publisher":"Greater Baltimore Medical Center","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Community Hospital Internal Medicine Perspectives"],"abstract":"<jats:p>Neurosyphilis is a condition characterized by insidious onset of encephalopathy and delirium. The infrequency with which it is encountered makes neurosyphilis a formidable diagnostic challenge. We present a rare case of a 71-year-old male with ischemic cardiomyopathy, chronic obstructive pulmonary disease (COPD), undifferentiated arthritis and alcohol use disorder who was brought to the emergency department after he was found altered, confused, and paranoid. His hospital stay was eventful for multiple episodes of agitation that were difficult to control despite benzodiazepines and high doses of antipsychotics. After an extensive workup, he was found to have neurosyphilis and his delirium resolved following a brief period of treatment. This case illustrates the importance of early suspicion for neurosyphilis as a cause of delirium, especially in endemic areas and in patients with focal neurologic findings.<\/jats:p>","DOI":"10.55729\/2000-9666.1416","type":"journal-article","created":{"date-parts":[[2024,11,3]],"date-time":"2024-11-03T04:28:43Z","timestamp":1730608123000},"page":"111-114","source":"Crossref","is-referenced-by-count":2,"title":["Neuropsychiatric Manifestations of Syphilis"],"prefix":"10.55729","volume":"14","author":[{"given":"Nadim","family":"Ojaimi","sequence":"first","affiliation":[{"name":"Medstar Health Internal Medicine Residency Program, Baltimore, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aida","family":"Metri","sequence":"additional","affiliation":[{"name":"Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher James","family":"Haas","sequence":"additional","affiliation":[{"name":"Department of Medicine, Georgetown University School of Medicine, Washington DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"34701","published-online":{"date-parts":[[2024,11,2]]},"container-title":["Journal of Community Hospital Internal Medicine Perspectives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/scholarlycommons.gbmc.org\/cgi\/viewcontent.cgi?article=1416&amp;context=jchimp","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T09:57:00Z","timestamp":1788602220000},"score":1,"resource":{"primary":{"URL":"https:\/\/scholarlycommons.gbmc.org\/jchimp\/vol14\/iss6\/20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,2]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,11,2]]}},"URL":"https:\/\/doi.org\/10.55729\/2000-9666.1416","relation":{},"ISSN":["2000-9666"],"issn-type":[{"value":"2000-9666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,2]]}}}