{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T10:13:03Z","timestamp":1788603183729,"version":"build-2803163510"},"reference-count":0,"publisher":"Greater Baltimore Medical Center","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Community Hospital Internal Medicine Perspectives"],"abstract":"<jats:p>Nitrous oxide (N\u2082O) has been increasingly used for recreational purposes due to its dissociative and euphoric properties. Exposure to N\u2082O results in the deactivation of in vivo vitamin B\u2081\u2082, leading to subsequent neurological sequelae due to vitamin B\u2081\u2082 deficiency (Hathout &amp; El-Saden, 2011). Current management focuses on cessation of exposure and replacement therapy, yet patients may continue to suffer from permanent neurological damage (Thompson et al., 2015). We report a case of a 50-year-old woman who presented with impaired balance, a subacute decline in mental status, multiple falls, and back pain. She was hospitalized for evaluation of her presenting symptoms and for pain management. The patient\u2019s sister helped uncover the patient\u2019s misuse of N\u2082O via \u201cWhip-it!\u201d cartridges. Physical examination, along with magnetic resonance imaging of the cervical and thoracic spine, confirmed the diagnosis of subacute combined degeneration (SCD), and appropriate treatment was initiated. Our case aims to bring attention to this seemingly harmless recreational drug that continues to regain popularity and its association with brain and nerve damage (van Amsterdam et al., 2015).<\/jats:p>","DOI":"10.55729\/2000-9666.1450","type":"journal-article","created":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T04:07:37Z","timestamp":1736050057000},"source":"Crossref","is-referenced-by-count":0,"title":["Whip-it Beyond Desserts: Causing Subacute Combined Degeneration - Case Report and Literature Review"],"prefix":"10.55729","volume":"15","author":[{"given":"Vijayalakshmi","family":"Brahmashettar","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Stanford University, Stanford,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elton","family":"Ahadov","sequence":"additional","affiliation":[{"name":"Internal Medicine Resident Physician, Luminis Health Anne Arundel Medical Center,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamilla","family":"Rzayeva","sequence":"additional","affiliation":[{"name":", Internal Medicine Resident Physician, Luminis Health Anne Arundel Medical Cente"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Westley T.","family":"Hartley","sequence":"additional","affiliation":[{"name":"Frostburg State University, Assistant Professor of Physician Assistant Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nargiz","family":"Muganlinskaya","sequence":"additional","affiliation":[{"name":"Program Director, Internal Medicine Residency Program, Luminis Health Anne Arundel Medical Center, Annapolis, MD, Clinical Associate Professor of Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"34701","published-online":{"date-parts":[[2025,1,4]]},"container-title":["Journal of Community Hospital Internal Medicine Perspectives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/scholarlycommons.gbmc.org\/cgi\/viewcontent.cgi?article=1450&amp;context=jchimp","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T09:56:25Z","timestamp":1788602185000},"score":1,"resource":{"primary":{"URL":"https:\/\/scholarlycommons.gbmc.org\/jchimp\/vol15\/iss1\/24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,4]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,4]]}},"URL":"https:\/\/doi.org\/10.55729\/2000-9666.1450","relation":{},"ISSN":["2000-9666"],"issn-type":[{"value":"2000-9666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,4]]}}}